Homo sapiens (human): 57142
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Entry
57142 CDS
T01001
Symbol
RTN4, ASY, NI220/250, NOGO, NSP, NSP-CL, Nbla00271, Nbla10545, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Name
(RefSeq) reticulon 4
KO
K20720
reticulon-4
Organism
hsa
Homo sapiens (human)
Pathway
hsa05010
Alzheimer disease
Drug target
Ozanezumab:
D10331
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
57142 (RTN4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
57142 (RTN4)
03036 Chromosome and associated proteins [BR:
hsa03036
]
57142 (RTN4)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Others
Others
57142 (RTN4)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Spindle formation proteins
57142 (RTN4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reticulon
DUF639
Motif
Other DBs
NCBI-GeneID:
57142
NCBI-ProteinID:
NP_065393
OMIM:
604475
HGNC:
14085
Ensembl:
ENSG00000115310
UniProt:
Q9NQC3
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(54972189..55137831)
Genome browser
AA seq
1192 aa
AA seq
DB search
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
NT seq
3579 nt
NT seq
+upstream
nt +downstream
nt
atggaagacctggaccagtctcctctggtctcgtcctcggacagcccaccccggccgcag
cccgcgttcaagtaccagttcgtgagggagcccgaggacgaggaggaagaagaggaggag
gaagaggaggacgaggacgaagacctggaggagctggaggtgctggagaggaagcccgcc
gccgggctgtccgcggccccagtgcccaccgcccctgccgccggcgcgcccctgatggac
ttcggaaatgacttcgtgccgccggcgccccggggacccctgccggccgctccccccgtc
gccccggagcggcagccgtcttgggacccgagcccggtgtcgtcgaccgtgcccgcgcca
tccccgctgtctgctgccgcagtctcgccctccaagctccctgaggacgacgagcctccg
gcccggcctccccctcctcccccggccagcgtgagcccccaggcagagcccgtgtggacc
ccgccagccccggctcccgccgcgcccccctccaccccggccgcgcccaagcgcaggggc
tcctcgggctcagtggatgagaccctttttgctcttcctgctgcatctgagcctgtgata
cgctcctctgcagaaaatatggacttgaaggagcagccaggtaacactatttcggctggt
caagaggatttcccatctgtcctgcttgaaactgctgcttctcttccttctctgtctcct
ctctcagccgcttctttcaaagaacatgaataccttggtaatttgtcaacagtattaccc
actgaaggaacacttcaagaaaatgtcagtgaagcttctaaagaggtctcagagaaggca
aaaactctactcatagatagagatttaacagagttttcagaattagaatactcagaaatg
ggatcatcgttcagtgtctctccaaaagcagaatctgccgtaatagtagcaaatcctagg
gaagaaataatcgtgaaaaataaagatgaagaagagaagttagttagtaataacatcctt
cataatcaacaagagttacctacagctcttactaaattggttaaagaggatgaagttgtg
tcttcagaaaaagcaaaagacagttttaatgaaaagagagttgcagtggaagctcctatg
agggaggaatatgcagacttcaaaccatttgagcgagtatgggaagtgaaagatagtaag
gaagatagtgatatgttggctgctggaggtaaaatcgagagcaacttggaaagtaaagtg
gataaaaaatgttttgcagatagccttgagcaaactaatcacgaaaaagatagtgagagt
agtaatgatgatacttctttccccagtacgccagaaggtataaaggatcgttcaggagca
tatatcacatgtgctccctttaacccagcagcaactgagagcattgcaacaaacattttt
cctttgttaggagatcctacttcagaaaataagaccgatgaaaaaaaaatagaagaaaag
aaggcccaaatagtaacagagaagaatactagcaccaaaacatcaaacccttttcttgta
gcagcacaggattctgagacagattatgtcacaacagataatttaacaaaggtgactgag
gaagtcgtggcaaacatgcctgaaggcctgactccagatttagtacaggaagcatgtgaa
agtgaattgaatgaagttactggtacaaagattgcttatgaaacaaaaatggacttggtt
caaacatcagaagttatgcaagagtcactctatcctgcagcacagctttgcccatcattt
gaagagtcagaagctactccttcaccagttttgcctgacattgttatggaagcaccattg
aattctgcagttcctagtgctggtgcttccgtgatacagcccagctcatcaccattagaa
gcttcttcagttaattatgaaagcataaaacatgagcctgaaaaccccccaccatatgaa
gaggccatgagtgtatcactaaaaaaagtatcaggaataaaggaagaaattaaagagcct
gaaaatattaatgcagctcttcaagaaacagaagctccttatatatctattgcatgtgat
ttaattaaagaaacaaagctttctgctgaaccagctccggatttctctgattattcagaa
atggcaaaagttgaacagccagtgcctgatcattctgagctagttgaagattcctcacct
gattctgaaccagttgacttatttagtgatgattcaatacctgacgttccacaaaaacaa
gatgaaactgtgatgcttgtgaaagaaagtctcactgagacttcatttgagtcaatgata
gaatatgaaaataaggaaaaactcagtgctttgccacctgagggaggaaagccatatttg
gaatcttttaagctcagtttagataacacaaaagataccctgttacctgatgaagtttca
acattgagcaaaaaggagaaaattcctttgcagatggaggagctcagtactgcagtttat
tcaaatgatgacttatttatttctaaggaagcacagataagagaaactgaaacgttttca
gattcatctccaattgaaattatagatgagttccctacattgatcagttctaaaactgat
tcattttctaaattagccagggaatatactgacctagaagtatcccacaaaagtgaaatt
gctaatgccccggatggagctgggtcattgccttgcacagaattgccccatgacctttct
ttgaagaacatacaacccaaagttgaagagaaaatcagtttctcagatgacttttctaaa
aatgggtctgctacatcaaaggtgctcttattgcctccagatgtttctgctttggccact
caagcagagatagagagcatagttaaacccaaagttcttgtgaaagaagctgagaaaaaa
cttccttccgatacagaaaaagaggacagatcaccatctgctatattttcagcagagctg
agtaaaacttcagttgttgacctcctgtactggagagacattaagaagactggagtggtg
tttggtgccagcctattcctgctgctttcattgacagtattcagcattgtgagcgtaaca
gcctacattgccttggccctgctctctgtgaccatcagctttaggatatacaagggtgtg
atccaagctatccagaaatcagatgaaggccacccattcagggcatatctggaatctgaa
gttgctatatctgaggagttggttcagaagtacagtaattctgctcttggtcatgtgaac
tgcacgataaaggaactcaggcgcctcttcttagttgatgatttagttgattctctgaag
tttgcagtgttgatgtgggtatttacctatgttggtgccttgtttaatggtctgacacta
ctgattttggctctcatttcactcttcagtgttcctgttatttatgaacggcatcaggca
cagatagatcattatctaggacttgcaaataagaatgttaaagatgctatggctaaaatc
caagcaaaaatccctggattgaagcgcaaagctgaatga
DBGET
integrated database retrieval system
