Homo sapiens (human): 57449
Entry
57449 CDS
T01001
Gene name
PLEKHG5, CMTRIC, DSMA4, GEF720, Syx, Tech
Definition
(RefSeq) pleckstrin homology and RhoGEF domain containing G5
KO
K19464
pleckstrin homology domain-containing family G member 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa05200
Pathways in cancer
Disease
H00264
Charcot-Marie-Tooth disease
H00856
Distal hereditary motor neuropathies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
57449 (PLEKHG5)
SSDB
Motif
Pfam:
RhoGEF
UNC-79
PH_10
PH_5
PH_13
PH_16
IQ_SEC7_PH
Other DBs
NCBI-GeneID:
57449
NCBI-ProteinID:
NP_001036128
OMIM:
611101
HGNC:
29105
Ensembl:
ENSG00000171680
Vega:
OTTHUMG00000000905
Pharos:
O94827
(Tbio)
UniProt:
O94827
LinkDB
Position
1p36.31
AA seq
1062 aa
MDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYD
GHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKA
RRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQ
SNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALER
VDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSSGSTNTGDSWKN
RAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYD
EDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLC
CLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKG
FKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKP
HQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSR
IDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVY
CFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTF
QASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEG
EDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQS
DETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAP
ESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSE
LCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGA
SPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
NT seq
3189 nt
+upstream
nt +downstream
nt
atggacgaccagagccccgctgaaaagaagggactgcgctgtcagaaccccgcctgcatg
gacaaggggcgggcggccaaggtatgtcaccacgccgactgccagcagctgcaccgccgg
gggcccctcaacctctgcgaggcctgtgacagcaagttccacagcaccatgcattatgat
gggcatgtccgcttcgaccttcccccacaaggctctgtgctggcccggaacgtgtccacc
cggtcatgcccgccgcgcaccagccccgcagtggacttggaggaggaggaggaggagagc
tctgtggatggcaaaggggaccggaagagcacaggcctgaaactctccaagaagaaagca
aggaggagacacacggatgacccaagcaaggaatgcttcactctgaaatttgacctgaat
gtggacattgagacagagatcgtcccagccatgaagaagaagtcactgggggaggtgctg
ctgcctgtatttgaaaggaagggcattgcgctgggcaaagtggacatctacctggaccag
tccaacacacccctgtccctcaccttcgaggcctacaggttcgggggacactaccttcgt
gtcaaagccccagccaagcctggagatgagggcaaggtggagcagggcatgaaggactcc
aagtccctgagtttgccgattctgcggccagctgggaccgggccccccgccctggagcgt
gtggacgcccagagccgccgggagagcctggacatcttggcccctggccgccgccgcaag
aacatgtcggagttcctgggggaggcgagcatccccgggcaggagccccccacgccctcc
agctgctctctgcccagcggcagcagtggcagcaccaacactggcgacagctggaagaac
cgggcggccagtcgcttcagcggctttttcagctccggccccagcaccagcgcctttggc
cgggaggtagacaagatggagcagctggagggcaagctgcacacctacagcctcttcggg
ctgcccaggctgccccgggggctgcgcttcgaccatgactcctgggaggaggagtacgat
gaagacgaggatgaggacaatgcctgcctgaggctggaggacagctggcgggagctcatt
gatgggcatgagaagctgacccggcggcagtgccaccagcaggaggcggtgtgggagctg
ctgcacacggaggcctcctacatcaggaaactgcgggtgatcatcaacctgttcctgtgc
tgcctcctgaacctgcaagagtcagggctgctgtgtgaggtggaggcggagcgcctgttc
agcaacatcccggagatcgcgcagctgcaccgcaggctgtgggctagcgtgatggcgccg
gtgctggagaaggcgcggcgcacgcgagcgctgctacagcccggggacttcctcaaaggc
ttcaagatgttcggctcgctcttcaagccctacatccgctactgcatggaggaggagggc
tgcatggagtacatgcgcggcctgctgcgcgacaacgacctcttccgggcctacatcacg
tgggcggagaagcacccacagtgccagaggctgaagctgagcgacatgctggccaaaccc
caccagcggctcaccaagtacccgctgctgctcaagtcggtgctgaggaagaccgaggag
ccgcgcgccaaggaggccgtcgtcgccatgatcggctccgtggagcgcttcatccaccac
gtgaacgcgtgcatgcggcagcggcaggagcggcagcggctggcggccgtggtgagccgc
atcgacgcctacgaggtggtggaaagcagcagcgacgaagtggacaagctcctgaaggaa
tttctgcacctggacttgacagcgcccatccctggcgcctccccggaggagacgcggcag
ctgctgctggaggggagcctgaggatgaaggaggggaaggacagcaagatggatgtgtac
tgcttcctcttcacggatctgctgttggtgaccaaagcagtgaagaaggcagagaggacc
agggtcatcaggccacccctgctcgtggacaagattgtgtgccgggagctacgggaccct
gggtccttcctccttatctacctgaatgagtttcacagtgctgtaggggcctacacgttc
caggccagtggccaggccttgtgccgtggctgggtggacaccatttacaatgcccagaac
cagctgcaacagctgcgtgcacaggagcccccaggcagtcagcagcccctgcagagcctg
gaagaggaggaggatgagcaggaggaggaagaggaggaggaggaggaggaggaggaaggc
gaggacagtggcacttcagctgccagctcccctaccatcatgcggaaaagcagcggcagc
cccgactctcagcactgtgcctcagatggctccacggagaccctggccatggttgtggta
gagcctggggacacgctgtcctcccccgagttcgacagcggtcctttcagctcccagtct
gatgagacctctctcagcaccactgcctcatctgccacgcccaccagtgagctgctgccc
ctgggtccggtggacggccgctcctgctccatggactctgcctacggcaccctctcccca
acctccttacaagactttgtggccccaggcccaatggcagagctagtgcctcgggcccca
gagtccccacgagttccttcccctccaccctcgccccgtctccgccgccgcacccctgtc
cagctgttgagctgcccgccccacctgctcaagtctaagtccgaggccagcctcctccag
ctgctggcaggggctggcacccatgggacaccctctgcccccagccgcagcctgtcagag
ctctgcctggctgttccagccccaggtattaggactcagggctcccctcaggaagctggg
cccagctgggattgccgaggggcccctagccctggcagcggtcctgggctagtcggctgc
ctggccggggaacctgcaggctcccacaggaagaggtgtggagacctgccctcgggggcc
tctcccagggtccagcctgagcccccaccaggggtctctgcccagcacaggaagctgacc
ctggcccagctctaccgaatcaggaccaccctgctgcttaactccacgctcactgcctcg
gaggtctga
DBGET
integrated database retrieval system
