KEGG   Homo sapiens (human): 5901Help
Entry
5901              CDS       T01001                                 

Gene name
RAN, ARA24, Gsp1, TC4
Definition
(RefSeq) RAN, member RAS oncogene family
  KO
K07936  GTP-binding nuclear protein Ran
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa03013  RNA transport
hsa05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    5901 (RAN)
   03008 Ribosome biogenesis in eukaryotes
    5901 (RAN)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    5901 (RAN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5901 (RAN)
   03009 Ribosome biogenesis [BR:hsa03009]
    5901 (RAN)
   03016 Transfer RNA biogenesis [BR:hsa03016]
    5901 (RAN)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5901 (RAN)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5901 (RAN)
   04031 GTP-binding proteins [BR:hsa04031]
    5901 (RAN)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     5901 (RAN)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic Type
  Pre-40S particles
   Export and cytoplasmic maturation factors
    5901 (RAN)
  Pre-60S particles
    5901 (RAN)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic Type
  tRNA transport factors
   tRNA export factors
    5901 (RAN)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     5901 (RAN)
   Spindle formation proteins
    5901 (RAN)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5901 (RAN)
GTP-binding proteins [BR:hsa04031]
 Small (Monomeric) G-proteins
  Ran Family
   Ran
    5901 (RAN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf MMR_HSR1 RNA_helicase GTP_EFTU Gtr1_RagA SRPRB G-alpha AAA_24 Pox_A32 AAA_7 ArgoMid Septin TsaE AAA_16 AAA_33
Motif
Other DBs
NCBI-GeneID: 5901
NCBI-ProteinID: NP_006316
OMIM: 601179
HGNC: 9846
Ensembl: ENSG00000132341
Vega: OTTHUMG00000134328
Pharos: P62826(Tbio)
UniProt: P62826
LinkDB All DBs
Structure
PDB: 

Position
12q24.33
AA seq 216 aa AA seqDB search
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NT seq 651 nt NT seq  +upstreamnt  +downstreamnt
atggctgcgcagggagagccccaggtccagttcaaacttgtattggttggtgatggtggt
actggaaaaacgaccttcgtgaaacgtcatttgactggtgaatttgagaagaagtatgta
gccaccttgggtgttgaggttcatcccctagtgttccacaccaacagaggacctattaag
ttcaatgtatgggacacagccggccaggagaaattcggtggactgagagatggctattat
atccaagcccagtgtgccatcataatgtttgatgtaacatcgagagttacttacaagaat
gtgcctaactggcatagagatctggtacgagtgtgtgaaaacatccccattgtgttgtgt
ggcaacaaagtggatattaaggacaggaaagtgaaggcgaaatccattgtcttccaccga
aagaagaatcttcagtactacgacatttctgccaaaagtaactacaactttgaaaagccc
ttcctctggcttgctaggaagctcattggagaccctaacttggaatttgttgccatgcct
gctctcgccccaccagaagttgtcatggacccagctttggcagcacagtatgagcacgac
ttagaggttgctcagacaactgctctcccggatgaggatgatgacctgtga

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