Homo sapiens (human): 64446
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Entry
64446 CDS
T01001
Gene name
DNAI2, CILD9, DIC2
Definition
(RefSeq) dynein axonemal intermediate chain 2
KO
K11143
dynein intermediate chain 2, axonemal
Organism
hsa
Homo sapiens (human)
Pathway
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06419
Microtubule-based transport
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
Element
N00976
Retrograde axonal transport
N00977
Mutation-caused aberrant Htt to retrograde axonal transport
N01159
Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160
Mutation-caused aberrant SOD1 to retrograde axonal transport
Disease
H00564
Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
64446 (DNAI2)
05016 Huntington disease
64446 (DNAI2)
05022 Pathways of neurodegeneration - multiple diseases
64446 (DNAI2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Dyneins
64446 (DNAI2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
WD40
DUF4795
Motif
Other DBs
NCBI-GeneID:
64446
NCBI-ProteinID:
NP_075462
OMIM:
605483
HGNC:
18744
Ensembl:
ENSG00000171595
Vega:
OTTHUMG00000178578
Pharos:
Q9GZS0
(Tbio)
UniProt:
Q9GZS0
LinkDB
All DBs
Position
17q25.1
AA seq
605 aa
AA seq
DB search
MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH
EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC
IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV
AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ
IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP
TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF
PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP
TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE
VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD
LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV
EEDLA
NT seq
1818 nt
NT seq
+upstream
nt +downstream
nt
atggagattgtgtacgtgtacgtcaagaagcgcagcgagttcgggaagcagtgcaatttc
tcggaccgccaggccgagctgaacatcgacatcatgcccaaccctgagctggccgagcag
ttcgtggagcggaacccagtggacacgggcatccagtgctcgatcagcatgtcggaacac
gaggccaactcagagcggtttgagatggagacccggggagttaaccatgtcgaggggggc
tggcccaaggacgtgaaccccctggagctggagcagaccatccgtttccggaagaaagtg
gagaaagatgagaactacgttaacgccatcatgcagctcggctctatcatggagcactgc
atcaagcagaacaatgccattgacatctatgaagagtatttcaatgacgaggaggccatg
gaagtgatggaggaggacccttcagctaaaaccatcaatgtgttcagggacccccaggaa
atcaagagggctgccacacacctctcctggcaccccgatggcaacaggaagttggcagtg
gcatactcctgcttggattttcagcgggcacctgtgggcatgagcagcgattcatacatc
tgggacctggaaaaccccaacaagcctgaacttgctctgaagccatcgtctccactcgtg
acgttggagttcaaccccaaagattcccacgtactcctgggtggctgctacaatggacag
atagcctgctgggacacccgaaagggcagcctggtggcggagctatccaccattgagtcc
agccaccgagaccctgtgtatggcaccatctggctgcagtcgaagacgggcaccgagtgc
ttctcagcttccacggatgggcaggtcatgtggtgggacatccgaaagatgagcgagccc
actgaagttgtgatcttggacatcaccaagaaggaacagttggaaaatgccttgggggcc
atctccctggagttcgaatctactttgcccaccaagttcatggtggggaccgagcagggc
atcgtcatctcctgcaaccgcaaggccaagacgtcagctgaaaagattgtgtgcaccttc
ccgggccatcatggccccatctacgccctccagagaaaccccttctacccgaagaacttc
ctgacggttggcgactggacagcccgcatttggtctgaagacagccgggaatcgtccatc
atgtggaccaagtaccacatggcttacctcactgatgctgcctggagccccgtgaggccg
accgttttctttaccaccaggatggacggaaccctggatatctgggacttcatgttcgag
cagtgcgatcccaccctcagcttgaaggtgtgtgacgaggccctcttctgcctccgggtg
caggacaatgggtgtctcatcgcctgcggctcccagctggggacaaccaccctgctggag
gtctcgcctgggctctctaccctccagaggaatgagaagaacgtagcctcttccatgttt
gagcgtgagacccggcgagagaagatcctggaggccaggcaccgggagatgcggctgaag
gagaagggtaaggcggagggcagggatgaggagcagaccgatgaggagctggccgtagac
ctggaggcgctggtcagcaaggccgaggaggagttcttcgacatcatcttcgcagagctg
aagaagaaggaggcagacgccataaagctgacgccagtgcctcagcaaccaagtccagaa
gaagaccaggtggtggaggagggagaggaagcagcgggggaagaaggggatgaagaagtg
gaagaagacttagcctag
DBGET
integrated database retrieval system
