Homo sapiens (human): 7067
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Entry
7067 CDS
T01001
Symbol
THRA, AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRalpha, THRalpha1, THRalpha2, TRalpha, TRalpha1, TRalpha2, c-ERBA-1, c-erbA
Name
(RefSeq) thyroid hormone receptor alpha
KO
K05547
thyroid hormone receptor alpha
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04919
Thyroid hormone signaling pathway
Network
nt06322
TRH-TSH-TH signaling
Element
N00798
Thyroid hormone signaling pathway
Disease
H00250
Congenital nongoitrous hypothyroidism (CHNG)
Drug target
Dextrothyroxine:
D03750
Levothyroxine (
DG00510
):
D08125
Levothyroxine sodium:
D01010
<JP/US>
D11113
<US>
Liothyronine (
DG01372
):
D08128
D08129
Liothyronine sodium:
D01011
<JP/US>
Thyroid (
DG01993
):
D01012
D06482
Tiratricol:
D07214
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
7067 (THRA)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
7067 (THRA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
7067 (THRA)
09183 Protein families: signaling and cellular processes
03310 Nuclear receptors [BR:
hsa03310
]
7067 (THRA)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Zinc finger
Cys4 thyroid hormone receptor-like
7067 (THRA)
Nuclear receptors [BR:
hsa03310
]
1. Thyroid hormone like
1A. Thyroid hormone receptor (THR)
7067 (THRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C4
Hormone_recep
Motif
Other DBs
NCBI-GeneID:
7067
NCBI-ProteinID:
NP_001177848
OMIM:
190120
HGNC:
11796
Ensembl:
ENSG00000126351
UniProt:
P10827
Structure
PDB
LinkDB
All DBs
Position
17:40062193..40093867
Genome browser
AA seq
490 aa
AA seq
DB search
MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKA
TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA
QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
PHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQL
GEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVC
EDLAGNAASP
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atggaacagaagccaagcaaggtggagtgtgggtcagacccagaggagaacagtgccagg
tcaccagatggaaagcgaaaaagaaagaacggccaatgttccctgaaaaccagcatgtca
gggtatatccctagttacctggacaaagacgagcagtgtgtcgtgtgtggggacaaggca
actggttatcactaccgctgtatcacttgtgagggctgcaagggcttctttcgccgcaca
atccagaagaacctccatcccacctattcctgcaaatatgacagctgctgtgtcattgac
aagatcacccgcaatcagtgccagctgtgccgcttcaagaagtgcatcgccgtgggcatg
gccatggacttggttctagatgactcgaagcgggtggccaagcgtaagctgattgagcag
aaccgggagcggcggcggaaggaggagatgatccgatcactgcagcagcgaccagagccc
actcctgaagagtgggatctgatccacattgccacagaggcccatcgcagcaccaatgcc
cagggcagccattggaaacagaggcggaaattcctgcccgatgacattggccagtcaccc
attgtctccatgccggacggagacaaggtggacctggaagccttcagcgagtttaccaag
atcatcaccccggccatcacccgtgtggtggactttgccaaaaaactgcccatgttctcc
gagctgccttgcgaagaccagatcatcctcctgaaggggtgctgcatggagatcatgtcc
ctgcgggcggctgtccgctacgaccctgagagcgacaccctgacgctgagtggggagatg
gctgtcaagcgggagcagctcaagaatggcggcctgggcgtagtctccgacgccatcttt
gaactgggcaagtcactctctgcctttaacctggatgacacggaagtggctctgctgcag
gctgtgctgctaatgtcaacagaccgctcgggcctgctgtgtgtggacaagatcgagaag
agtcaggaggcgtacctgctggcgttcgagcactacgtcaaccaccgcaaacacaacatt
ccgcacttctggcccaagctgctgatgaaggagagagaagtgcagagttcgattctgtac
aagggggcagcggcagaaggccggccgggcgggtcactgggcgtccacccggaaggacag
cagcttctcggaatgcatgttgttcagggtccgcaggtccggcagcttgagcagcagctt
ggtgaagcgggaagtctccaagggccggttcttcagcaccagagcccgaagagcccgcag
cagcgtctcctggagctgctccaccgaagcggaattctccatgcccgagcggtctgtggg
gaagacgacagcagtgaggcggactccccgagctcctctgaggaggaaccggaggtctgc
gaggacctggcaggcaatgcagcctctccctga
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