Homo sapiens (human): 7389 Help Entry 7389              CDS       T01001                                  Gene name UROD, PCT, UPD Definition (RefSeq) uroporphyrinogen decarboxylase   KO K01599   uroporphyrinogen decarboxylase [EC:4.1.1.37] Organism hsa  Homo sapiens (human) Pathway hsa00860   Porphyrin and chlorophyll metabolism hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors Module hsa_M00868   Heme biosynthesis, animals and fungi, glycine => heme Network nt06011  Heme biosynthesis   Element N00601   Heme biosynthesis N00602   FECH deficiency in heme biosynthesis N00603   PPOX deficiency in heme biosynthesis N00604   CPOX deficiency in heme biosynthesis N00605   UROD deficiency in heme biosynthesis Disease H00201   Erythropoietic porphyria H00202   Hepatic porphyria H01763   Porphyria Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00860 Porphyrin and chlorophyll metabolism     7389 (UROD) Enzymes [BR:hsa01000]  4. Lyases   4.1  Carbon-carbon lyases    4.1.1  Carboxy-lyases     4.1.1.37  uroporphyrinogen decarboxylase      7389 (UROD) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  URO-D Motif Other DBs NCBI-GeneID:  7389 NCBI-ProteinID:  NP_000365 OMIM:  613521 HGNC:  12591 Ensembl:  ENSG00000126088 Vega:  OTTHUMG00000008949 Pharos:  P06132(Tbio) UniProt:  P06132 LinkDB All DBs Structure PDB:  1R3S 3GW3 1R3Q 1R3T 1R3W 1R3Y 1URO 1R3R 2Q71 1R3V 3GW0 2Q6Z 3GVQ 1JPH 3GVR 1JPK 1JPI 3GVV 3GVW Thumbnails Position 1p34.1 AA seq 367 aa AA seqDB search MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCR SPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLER LRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRW LYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDV AKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVT LQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKH SRLLRQN NT seq 1104 nt NT seq  +upstreamnt  +downstreamnt atggaagcgaatgggttgggacctcagggttttccggagctgaagaatgacacattcctg cgagcagcctggggagaggaaacagactacactcccgtttggtgcatgcgccaggcaggc cgttacttaccagagtttagggaaacccgggctgcccaggactttttcagcacgtgtcgc tctcctgaggcctgctgtgaactgactctgcagccactgcgtcgcttccctctggatgct gccatcattttctccgacatccttgttgtaccccaggcactgggcatggaggtgaccatg gtacctggcaaaggacccagcttcccagagccattaagagaagagcaggacctagaacgc ctacgggatccagaagtggtagcctctgagctaggctatgtgttccaagccatcaccctt acccgacaacgactggctggacgtgtgccgctgattggctttgctggtgccccatggacc ctgatgacatacatggttgagggtggtggctcaagcaccatggctcaggccaagcgctgg ctctatcagagacctcaggctagtcaccagctgcttcgcatcctcactgatgctctggtc ccatatctggtaggacaagtggtggctggtgcccaggcattgcagctgtttgagtcccat gcagggcatcttggcccacagctcttcaacaagtttgcactgccttacatccgtgatgtg gccaagcaagtgaaggccaggttgcgggaggcaggcctggcaccagtgcccatgatcatc tttgctaaggatgggcattttgccctggaggagctggcccaagctggctatgaggtggtt gggcttgactggacagtggccccaaagaaagcccgggagtgtgtggggaagacggtgaca ttgcagggcaacctggacccctgtgccttgtatgcatctgaggaggagatcgggcagttg gtgaagcagatgctggatgactttggaccacatcgctacattgccaacctgggccatggg ctttatcctgacatggacccagaacatgtgggcgcctttgtggatgctgtgcataaacac tcacgtctgcttcgacagaactga

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