KEGG   Homo sapiens (human): 7442Help
Entry
7442              CDS       T01001                                 

Gene name
TRPV1, VR1
Definition
(RefSeq) transient receptor potential cation channel subfamily V member 1
  KO
K05222  transient receptor potential cation channel subfamily V member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Drug target
Capsaicin: D00250
Mavatrep: D10370
Nonivamide: D08282
Olvanil: D05249
Zucapsaicin: D06388
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    7442 (TRPV1)
 Organismal Systems
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    7442 (TRPV1)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7442 (TRPV1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ion_trans Ank_2 Ank Ank_5 Ank_3 Ank_4
Motif
Other DBs
NCBI-GeneID: 7442
NCBI-ProteinID: NP_061197
OMIM: 602076
HGNC: 12716
Ensembl: ENSG00000196689
Vega: OTTHUMG00000177649
Pharos: Q8NER1(Tclin)
UniProt: Q8NER1
LinkDB All DBs
Position
17p13.2
AA seq 839 aa AA seqDB search
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
NT seq 2520 nt NT seq  +upstreamnt  +downstreamnt
atgaagaaatggagcagcacagacttgggggcagctgcggacccactccaaaaggacacc
tgcccagaccccctggatggagaccctaactccaggccacctccagccaagccccagctc
tccacggccaagagccgcacccggctctttgggaagggtgactcggaggaggctttcccg
gtggattgccctcacgaggaaggtgagctggactcctgcccgaccatcacagtcagccct
gttatcaccatccagaggccaggagacggccccaccggtgccaggctgctgtcccaggac
tctgtcgccgccagcaccgagaagaccctcaggctctatgatcgcaggagtatctttgaa
gccgttgctcagaataactgccaggatctggagagcctgctgctcttcctgcagaagagc
aagaagcacctcacagacaacgagttcaaagaccctgagacagggaagacctgtctgctg
aaagccatgctcaacctgcacgacggacagaacaccaccatccccctgctcctggagatc
gcgcggcaaacggacagcctgaaggagcttgtcaacgccagctacacggacagctactac
aagggccagacagcactgcacatcgccatcgagagacgcaacatggccctggtgaccctc
ctggtggagaacggagcagacgtccaggctgcggcccatggggacttctttaagaaaacc
aaagggcggcctggattctacttcggtgaactgcccctgtccctggccgcgtgcaccaac
cagctgggcatcgtgaagttcctgctgcagaactcctggcagacggccgacatcagcgcc
agggactcggtgggcaacacggtgctgcacgccctggtggaggtggccgacaacacggcc
gacaacacgaagtttgtgacgagcatgtacaatgagattctgatgctgggggccaaactg
cacccgacgctgaagctggaggagctcaccaacaagaagggaatgacgccgctggctctg
gcagctgggaccgggaagatcggggtcttggcctatattctccagcgggagatccaggag
cccgagtgcaggcacctgtccaggaagttcaccgagtgggcctacgggcccgtgcactcc
tcgctgtacgacctgtcctgcatcgacacctgcgagaagaactcggtgctggaggtgatc
gcctacagcagcagcgagacccctaatcgccacgacatgctcttggtggagccgctgaac
cgactcctgcaggacaagtgggacagattcgtcaagcgcatcttctacttcaacttcctg
gtctactgcctgtacatgatcatcttcaccatggctgcctactacaggcccgtggatggc
ttgcctccctttaagatggaaaaaactggagactatttccgagttactggagagatcctg
tctgtgttaggaggagtctacttctttttccgagggattcagtatttcctgcagaggcgg
ccgtcgatgaagaccctgtttgtggacagctacagtgagatgcttttctttctgcagtca
ctgttcatgctggccaccgtggtgctgtacttcagccacctcaaggagtatgtggcttcc
atggtattctccctggccttgggctggaccaacatgctctactacacccgcggtttccag
cagatgggcatctatgccgtcatgatagagaagatgatcctgagagacctgtgccgtttc
atgtttgtctacatcgtcttcttgttcgggttttccacagcggtggtgacgctgattgaa
gacgggaagaatgactccctgccgtctgagtccacgtcgcacaggtggcgggggcctgcc
tgcaggccccccgatagctcctacaacagcctgtactccacctgcctggagctgttcaag
ttcaccatcggcatgggcgacctggagttcactgagaactatgacttcaaggctgtcttc
atcatcctgctgctggcctatgtaattctcacctacatcctcctgctcaacatgctcatc
gccctcatgggtgagactgtcaacaagatcgcacaggagagcaagaacatctggaagctg
cagagagccatcaccatcctggacacggagaagagcttccttaagtgcatgaggaaggcc
ttccgctcaggcaagctgctgcaggtggggtacacacctgatggcaaggacgactaccgg
tggtgcttcagggtggacgaggtgaactggaccacctggaacaccaacgtgggcatcatc
aacgaagacccgggcaactgtgagggcgtcaagcgcaccctgagcttctccctgcggtca
agcagagtttcaggcagacactggaagaactttgccctggtcccccttttaagagaggca
agtgctcgagataggcagtctgctcagcccgaggaagtttatctgcgacagttttcaggg
tctctgaagccagaggacgctgaggtcttcaagagtcctgccgcttccggggagaagtga

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