KEGG   Homo sapiens (human): 7855Help
Entry
7855              CDS       T01001                                 

Gene name
FZD5, C2orf31, HFZ5
Definition
(RefSeq) frizzled class receptor 5
  KO
K02375  frizzled 5/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa04310  Wnt signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04916  Melanogenesis
hsa04934  Cushing syndrome
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05205  Proteoglycans in cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Network
nt06115  WNT signaling (virus)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06215  WNT signaling
nt06260  Colorectal cancer
nt06261  Gastric cancer
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
nt06271  Endometrial cancer
nt06274  Thyroid cancer
  Element
N00056  Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    7855 (FZD5)
   04390 Hippo signaling pathway
    7855 (FZD5)
   04150 mTOR signaling pathway
    7855 (FZD5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    7855 (FZD5)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    7855 (FZD5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7855 (FZD5)
   05205 Proteoglycans in cancer
    7855 (FZD5)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    7855 (FZD5)
   05226 Gastric cancer
    7855 (FZD5)
   05217 Basal cell carcinoma
    7855 (FZD5)
   05224 Breast cancer
    7855 (FZD5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    7855 (FZD5)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    7855 (FZD5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    7855 (FZD5)
G protein-coupled receptors [BR:hsa04030]
 Frizzled / Smoothened family
  7855 (FZD5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Frizzled Fz
Motif
Other DBs
NCBI-GeneID: 7855
NCBI-ProteinID: NP_003459
OMIM: 601723
HGNC: 4043
Ensembl: ENSG00000163251
Vega: OTTHUMG00000154790
Pharos: Q13467(Tbio)
UniProt: Q13467
LinkDB All DBs
Structure
PDB: 

Position
2q33.3
AA seq 585 aa AA seqDB search
MARPDPSAPPSLLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQ
DEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLM
RQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLPGPPGAPASGG
ECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIG
LWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSR
EHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYF
HLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLL
AGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEA
ALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRFTSRCCCR
PRRGHKSGGAMAAGDYPEASAALTGRTGPPGPAATYHKQVSLSHV
NT seq 1758 nt NT seq  +upstreamnt  +downstreamnt
atggctcggcctgacccatccgcgccgccctcgctgttgctgctgctcctagcgcagctg
gtgggccgggcggccgccgcgtccaaggccccggtgtgccaggaaatcacggtgcccatg
tgccgcggcatcggctacaacctgacgcacatgcccaaccagttcaaccacgacacgcag
gacgaggcgggcctggaggtgcaccagttctggccgctggtggagatccaatgctcgccg
gacctgcgcttcttcctatgctctatgtacacgcccatctgtctgcccgactaccacaag
ccgctgccgccctgccgctcggtgtgcgagcgcgccaaggccggctgctcgccgctgatg
cgccagtacggcttcgcctggcccgagcgcatgagctgcgaccgcctcccggtgctgggc
cgcgacgccgaggtcctctgcatggattacaaccgcagcgaggccaccacggcgcccccc
aggcctttcccagccaagcccacccttccaggcccgccaggggcgccggcctcggggggc
gaatgccccgctgggggcccgttcgtgtgcaagtgtcgcgagcccttcgtgcccattctg
aaggagtcacacccgctctacaacaaggtgcggacgggccaggtgcccaactgcgcggta
ccctgctaccagccgtccttcagtgccgacgagcgcacgttcgccaccttctggataggc
ctgtggtcggtgctgtgcttcatctccacgtccaccacagtggccaccttcctcatcgac
atggaacgcttccgctatcctgagcgccccatcatcttcctgtcagcctgctacctgtgc
gtgtcgctgggcttcctggtgcgtctggtcgtgggccatgccagcgtggcctgcagccgc
gagcacaaccacatccactacgagaccacgggccctgcactgtgcaccatcgtcttcctc
ctggtctacttcttcggcatggccagctccatctggtgggtcatcctgtcgctcacctgg
ttcctggccgccggcatgaagtggggcaacgaggccatcgcgggctacgcgcagtacttc
cacctggctgcgtggctcatccccagcgtcaagtccatcacggcactggcgctgagctcc
gtggacggggacccagtggccggcatctgctacgtgggcaaccagaacctgaactcgctg
cgcggcttcgtgctgggcccgctggtgctctacctgctggtgggcacgctcttcctgctg
gcgggcttcgtgtcgctcttccgcatccgcagcgtcatcaagcagggcggcaccaagacg
gacaagctggagaagctcatgatccgcatcggcatcttcacgctgctctacacggtcccc
gccagcattgtggtggcctgctacctgtacgagcagcactaccgcgagagctgggaggcg
gcgctcacctgcgcctgcccgggccacgacaccggccagccgcgcgccaagcccgagtac
tgggtgctcatgctcaagtacttcatgtgcctggtggtgggcatcacgtcgggcgtctgg
atctggtcgggcaagacggtggagtcgtggcggcgtttcaccagccgctgctgctgccgc
ccgcggcgcggccacaagagcgggggcgccatggccgcaggggactaccccgaggcgagc
gccgcgctcacaggcaggaccgggccgccgggccccgccgccacctaccacaagcaggtg
tccctgtcgcacgtgtag

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