Homo sapiens (human): 83933
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Entry
83933 CDS
T01001
Symbol
HDAC10, HD10
Name
(RefSeq) histone deacetylase 10
KO
K18671
histone deacetylase 10 [EC:
3.5.1.98
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04613
Neutrophil extracellular trap formation
hsa05034
Alcoholism
hsa05203
Viral carcinogenesis
Drug target
Abexinostat (
DG01402
):
D10060
D10084
Belinostat:
D08870
<US>
Bocodepsin (
DG03260
):
D12551
D12552
Entinostat:
D09338
Fimepinostat:
D11319
Givinostat (
DG03284
):
D12742
D12743
<US>
Panobinostat (
DG01403
):
D10019
D10319
Quisinostat (
DG01407
):
D10321
D10322
Remetinostat:
D10977
Resminostat:
D13021
Romidepsin:
D06637
<JP/US>
Tucidinostat:
D10993
<JP>
Vorinostat:
D06320
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
83933 (HDAC10)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
83933 (HDAC10)
09165 Substance dependence
05034 Alcoholism
83933 (HDAC10)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
83933 (HDAC10)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.98 histone deacetylase
83933 (HDAC10)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
Class II HDACs
83933 (HDAC10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hist_deacetyl
Motif
Other DBs
NCBI-GeneID:
83933
NCBI-ProteinID:
NP_114408
OMIM:
608544
HGNC:
18128
Ensembl:
ENSG00000100429
UniProt:
Q969S8
LinkDB
All DBs
Position
22:complement(50245183..50251265)
Genome browser
AA seq
669 aa
AA seq
DB search
MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEEL
GLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTG
AVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQ
YLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVA
AFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAV
LEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQ
DVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPD
ITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIA
ATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALS
MFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGL
AGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM
LQCHPHLVA
NT seq
2010 nt
NT seq
+upstream
nt +downstream
nt
atggggaccgcgcttgtgtaccatgaggacatgacggccacccggctgctctgggacgac
cccgagtgcgagatcgagcgtcctgagcgcctgaccgcagccctggatcgcctgcggcag
cgcggcctggaacagaggtgtctgcggttgtcagcccgcgaggcctcggaagaggagctg
ggcctggtgcacagcccagagtatgtatccctggtcagggagacccaggtcctaggcaag
gaggagctgcaggcgctgtccggacagttcgacgccatctacttccacccgagtaccttt
cactgcgcgcggctggccgcaggggctggactgcagctggtggacgctgtgctcactgga
gctgtgcaaaatgggcttgccctggtgaggcctcccgggcaccatggccagagggcggct
gccaacgggttctgtgtgttcaacaacgtggccatagcagctgcacatgccaagcagaaa
cacgggctacacaggatcctcgtcgtggactgggatgtgcaccatggccaggggatccag
tatctctttgaggatgaccccagcgtcctttacttctcctggcaccgctatgagcatggg
cgcttctggcctttcctgcgagagtcagatgcagacgcagtggggcggggacagggcctc
ggcttcactgtcaacctgccctggaaccaggttgggatgggaaacgctgactacgtggct
gccttcctgcacctgctgctcccactggcctttgagtttgaccctgagctggtgctggtc
tcggcaggatttgactcagccatcggggaccctgaggggcaaatgcaggccacgccagag
tgcttcgcccacctcacacagctgctgcaggtgctggccggcggccgggtctgtgccgtg
ctggagggcggctaccacctggagtcactggcggagtcagtgtgcatgacagtacagacg
ctgctgggtgacccggccccacccctgtcagggccaatggcgccatgtcagagtgcccta
gagtccatccagagtgcccgtgctgcccaggccccgcactggaagagcctccagcagcaa
gatgtgaccgctgtgccgatgagccccagcagccactccccagaggggaggcctccacct
ctgctgcctgggggtccagtgtgtaaggcagctgcatctgcaccgagctccctcctggac
cagccgtgcctctgccccgcaccctctgtccgcaccgctgttgccctgacaacgccggat
atcacattggttctgccccctgacgtcatccaacaggaagcgtcagccctgagggaggag
acagaagcctgggccaggccacacgagtccctggcccgggaggaggccctcactgcactt
gggaagctcctgtacctcttagatgggatgctggatgggcaggtgaacagtggtatagca
gccactccagcctctgctgcagcagccaccctggatgtggctgttcggagaggcctgtcc
cacggagcccagaggctgctgtgcgtggccctgggacagctggaccggcctccagacctc
gcccatgacgggaggagtctgtggctgaacatcaggggcaaggaggcggctgccctatcc
atgttccatgtctccacgccactgccagtgatgaccggtggtttcctgagctgcatcttg
ggcttggtgctgcccctggcctatggcttccagcctgacctggtgctggtggcgctgggg
cctggccatggcctgcagggcccccacgctgcactcctggctgcaatgcttcgggggctg
gcagggggccgagtcctggccctcctggaggagaactccacaccccagctagcagggatc
ctggcccgggtgctgaatggagaggcacctcctagcctaggcccttcctctgtggcctcc
ccagaggacgtccaggccctgatgtacctgagagggcagctggagcctcagtggaagatg
ttgcagtgccatcctcacctggtggcttga
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integrated database retrieval system
