Homo sapiens (human): 8749
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Entry
8749 CDS
T01001
Symbol
ADAM18, ADAM27, tMDCIII
Name
(RefSeq) ADAM metallopeptidase domain 18
KO
K16909
disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
8749 (ADAM18)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
8749 (ADAM18)
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Gene cluster
GFIT
Motif
Pfam:
Reprolysin
ADAM_CR
Disintegrin
Pep_M12B_propep
Reprolysin_3
ADAMTS_CR_2
EGF_2
EB
Motif
Other DBs
NCBI-GeneID:
8749
NCBI-ProteinID:
NP_055052
OMIM:
619495
HGNC:
196
Ensembl:
ENSG00000168619
UniProt:
Q9Y3Q7
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All DBs
Position
8:39584568..39730065
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AA seq
739 aa
AA seq
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MFLLLALLTELGRLQAHEGSEGIFLHVTVPRKIKSNDSEVSERKMIYIITIDGQPYTLHL
GKQSFLPQNFLVYTYNETGSLHSVSPYFMMHCHYQGYAAEFPNSFVTLSICSGLRGFLQF
ENISYGIEPVESSARFEHIIYQMKNNDPNVSILAVNYSHIWQKDQPYKVPLNSQIKNLSK
LLPQYLEIYIIVEKALYDYMGSEMMAVTQKIVQVIGLVNTMFTQFKLTVILSSLELWSNE
NQISTSGDADDILQRFLAWKRDYLILRPHDIAYLLVYRKHPKYVGATFPGTVCNKSYDAG
IAMYPDAIGLEGFSVIIAQLLGLNVGLTYDDITQCFCLRATCIMNHEAVSASGRKIFSNC
SMHDYRYFVSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDY
NTCKLKGSVKCGSGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNG
RLCKLGTAYCYNGQCQTTDNQCAKIFGKGAQGAPFACFKEVNSLHERSENCGFKNSQPLP
CERKDVLCGKLACVQPHKNANKSDAQSTVYSYIQDHVCVSIATGSSMRSDGTDNAYVADG
TMCGPEMYCVNKTCRKVHLMGYNCNATTKCKGKGICNNFGNCQCFPGHRPPDCKFQFGSP
GGSIDDGNFQKSGDFYTEKGYNTHWNNWFILSFCIFLPFFIVFTTVIFKRNEISKSCNRE
NAEYNRNSSVVSESDDVGH
NT seq
2220 nt
NT seq
+upstream
nt +downstream
nt
atgttccttctcctcgccctcctcactgagcttggaagactgcaagcccacgaaggttct
gaaggaatatttctgcatgtcacagttccacggaagattaagtcaaatgacagtgaagtt
tcagagaggaagatgatttacatcattacaattgatggacaaccttacactctacatctc
ggaaaacaatcattcttaccccagaactttttggtttatacatataatgaaactggatct
ttgcattctgtgtctccatattttatgatgcattgccattaccaaggatatgctgccgaa
tttccaaattcatttgtgacactcagtatatgttctggtctcaggggatttctccagttt
gaaaatatcagttatggaattgaaccagtagaatcttcagcaagatttgagcatataatt
tatcaaatgaaaaataatgatccaaatgtatccattttagcagtaaattacagtcatatt
tggcagaaagaccagccctacaaagttcctttaaactcacagataaaaaatctttcaaaa
ctattaccccaatatctggaaatatacattatagtggaaaaagctttgtatgattatatg
ggatctgaaatgatggctgtaacacaaaaaattgtccaggttattgggcttgtcaacact
atgtttacccagttcaaattgactgttatactgtcttccttggaattgtggtcaaatgaa
aaccagatttccaccagtggggatgctgatgatatattacaaagatttttggcatggaaa
cgggactatctcatcctacggccccatgacatagcatacttacttgtttacaggaaacat
cctaaatatgtgggagcaacatttcctggcactgtatgcaataaaagctatgatgcaggt
attgctatgtatccagatgcaataggtttggagggattttcggttattatagctcaactg
cttggccttaatgtaggattaacatatgatgacatcactcagtgtttctgtctgagagct
acatgcatcatgaatcatgaagcagtgagtgccagtggtagaaagatttttagcaactgc
agcatgcacgactatagatattttgtttcaaaatttgagactaaatgccttcagaagctt
tcaaatttgcaaccattacatcaaaatcaaccagtgtgtggtaatgggattttggaatcc
aatgaagaatgtgactgtggtaataaaaatgaatgtcaatttaagaagtgctgtgattat
aacacatgtaaactgaagggctcagtaaaatgtggttctggaccatgttgtacatcaaag
tgtgagttgtcaatagcaggcactccatgtagaaagagtattgatccagagtgtgatttt
acagagtactgcaatggaacctctagtaattgtgttcctgacacttatgcattgaatggc
cgtttgtgcaagttgggaactgcctattgctataacggacaatgtcaaactactgataac
cagtgtgccaagatatttggaaaaggtgctcaaggtgctccatttgcctgttttaaagaa
gttaattctctgcatgaaagatctgaaaactgtggttttaaaaattcacaaccattacct
tgtgaacggaaggatgttctctgtggaaaattagcttgtgttcagccacataaaaatgct
aataaaagtgacgctcaatctacagtttattcatatattcaagaccatgtatgtgtatct
atagccactggttcctccatgagatcagatggaacagacaatgcctatgtggctgatggc
accatgtgtggtccagaaatgtactgtgtaaataaaacctgcagaaaagttcatttaatg
ggatataactgtaatgccaccacaaaatgcaaagggaaagggatatgtaataattttggt
aattgtcaatgcttccctggacatagacctccagattgtaaattccagtttggttcccca
gggggtagtattgatgatggaaattttcagaaatctggtgacttttatactgaaaaaggc
tacaatacacactggaacaactggtttattctgagtttctgcatttttctgccgtttttc
atagttttcaccactgtgatctttaaaagaaatgaaataagtaaatcatgtaacagagag
aatgcagagtataatcgtaattcatccgttgtatcagaaagcgatgacgtgggacattaa
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