KEGG   VARIANT: 1045v1Help
Entry
1045v1                      Variant                                

Name
CDX2 overexpression
Gene
CDX2  caudal type homeobox 2 [KO:K22234]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06240  Transcription
nt06261  Gastric cancer
  Element
N00250  CDX2-overexpression to transcriptional activation
N00251  CDX2-overexpression to transcriptional repression
Reference
  Authors
Almeida R, Silva E, Santos-Silva F, Silberg DG, Wang J, De Bolos C, David L
  Title
Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas.
  Journal
J Pathol 199:36-40 (2003)
DOI:10.1002/path.1246
Reference
  Authors
Tan P, Yeoh KG
  Title
Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma.
  Journal
Gastroenterology 149:1153-1162.e3 (2015)
DOI:10.1053/j.gastro.2015.05.059
Reference
  Authors
Yuasa Y
  Title
Control of gut differentiation and intestinal-type gastric carcinogenesis.
  Journal
Nat Rev Cancer 3:592-600 (2003)
DOI:10.1038/nrc1141
Reference
  Authors
Vauhkonen M, Vauhkonen H, Sipponen P
  Title
Pathology and molecular biology of gastric cancer.
  Journal
Best Pract Res Clin Gastroenterol 20:651-74 (2006)
DOI:10.1016/j.bpg.2006.03.016
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