KEGG   VARIANT: 2078v1Help
Entry
2078v1                      Variant                                

Name
TMPRSS2-ERG fusion
Gene
ERG  ETS transcription factor ERG [KO:K09435]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
deletion del(21)(q22.2;q22.3)
COSF: 121 125 128
Variation
inversion inv(21)(q22.2;q22.3)
COSF: 121 125 128
Network
nt06240  Transcription
nt06272  Prostate cancer
  Element
N00128  TMPRSS2-ERG fusion to transcriptional activation
N00129  TMPRSS2-ERG fusion to transcriptional repression
Reference
  Authors
Brenner JC, Chinnaiyan AM
  Title
Translocations in epithelial cancers.
  Journal
Biochim Biophys Acta 1796:201-15 (2009)
DOI:10.1016/j.bbcan.2009.04.005
Reference
  Authors
Prensner JR, Chinnaiyan AM
  Title
Oncogenic gene fusions in epithelial carcinomas.
  Journal
Curr Opin Genet Dev 19:82-91 (2009)
DOI:10.1016/j.gde.2008.11.008
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