KEGG   VARIANT: 2122v1Help
Entry
2122v1                      Variant                                

Name
EVI1 overexpression
Gene
MECOM  MDS1 and EVI1 complex locus [KO:K04462]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06218  TGFB signaling
nt06276  Chronic myeloid leukemia
  Element
N00107  EVI-1 overexpression to TGF-beta signaling pathway
Reference
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
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