Entry |
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Name |
MET kinase domain mutation
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Gene |
MET MET proto-oncogene, receptor tyrosine kinase [KO: K05099]
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Organism |
hsa_var Human gene variants (Homo sapiens)
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Variation |
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Variation |
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Network |
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Element |
N00005 | Mutation-activated MET to RAS-ERK signaling pathway |
N00044 | Mutation-activated MET to PI3K signaling pathway |
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Reference |
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Authors |
Schmidt L, Junker K, Nakaigawa N, Kinjerski T, Weirich G, Miller M, Lubensky I, Neumann HP, Brauch H, Decker J, Vocke C, Brown JA, Jenkins R, Richard S, Bergerheim U, Gerrard B, Dean M, Linehan WM, Zbar B |
Title |
Novel mutations of the MET proto-oncogene in papillary renal carcinomas. |
Journal |
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Reference |
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Authors |
Park WS, Dong SM, Kim SY, Na EY, Shin MS, Pi JH, Kim BJ, Bae JH, Hong YK, Lee KS, Lee SH, Yoo NJ, Jang JJ, Pack S, Zhuang Z, Schmidt L, Zbar B, Lee JY |
Title |
Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. |
Journal |
Cancer Res 59:307-10 (1999) |
LinkDB |
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