KEGG   VARIANT: 4297v1Help
Entry
4297v1                      Variant                                

Name
MLL-AF4 fusion
Gene
KMT2A  lysine methyltransferase 2A [KO:K09186]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
translocation t(4;11)
COSF: 1947 2067 1949
Network
nt06240  Transcription
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Reference
  Authors
Guenther MG, Lawton LN, Rozovskaia T, Frampton GM, Levine SS, Volkert TL, Croce CM, Nakamura T, Canaani E, Young RA
  Title
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
  Journal
Genes Dev 22:3403-8 (2008)
DOI:10.1101/gad.1741408
Reference
  Authors
Slany RK
  Title
The molecular biology of mixed lineage leukemia.
  Journal
Haematologica 94:984-93 (2009)
DOI:10.3324/haematol.2008.002436
LinkDB All DBs

KEGG   VARIANT: 4299v1Help
Entry
4299v1                      Variant                                

Name
MLL-AF4 fusion
Gene
AFF1  AF4/FMR2 family member 1 [KO:K15184]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
translocation t(4;11)
COSF: 1947 2067 1949
Network
nt06240  Transcription
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Reference
  Authors
Guenther MG, Lawton LN, Rozovskaia T, Frampton GM, Levine SS, Volkert TL, Croce CM, Nakamura T, Canaani E, Young RA
  Title
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
  Journal
Genes Dev 22:3403-8 (2008)
DOI:10.1101/gad.1741408
Reference
  Authors
Slany RK
  Title
The molecular biology of mixed lineage leukemia.
  Journal
Haematologica 94:984-93 (2009)
DOI:10.3324/haematol.2008.002436
LinkDB All DBs

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