KEGG   VARIANT: 5371v1Help
Entry
5371v1                      Variant                                

Name
PML-RARA fusion
Gene
PML  promyelocytic leukemia [KO:K10054]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
translocation t(15;17)(q22;q12)
COSF: 2300 2302 2304
Network
nt06240  Transcription
nt06275  Acute myeloid leukemia
  Element
N00109  PML-RARA fusion to transcriptional activtion
N00113  PML-RARA fusion to transcriptional repression
Reference
  Authors
Scandura JM, Boccuni P, Cammenga J, Nimer SD
  Title
Transcription factor fusions in acute leukemia: variations on a theme.
  Journal
Oncogene 21:3422-44 (2002)
DOI:10.1038/sj.onc.1205315
Reference
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
  Authors
Saultz JN, Garzon R
  Title
Acute Myeloid Leukemia: A Concise Review.
  Journal
J Clin Med 5:E33 (2016)
DOI:10.3390/jcm5030033
LinkDB All DBs

DBGET integrated database retrieval system