KEGG   VARIANT: 7048v2
Entry
7048v2                      Variant                                

Name
TGFBR2 reduced expression
Gene
TGFBR2  transforming growth factor beta receptor 2 [KO:K04388]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
reduced expression
Network
nt06218  TGFB signaling
nt06263  Hepatocellular carcinoma
  Element
N00241  TGFBR2-reduced expression to TGF-beta signaling pathway
Reference
PMID:9815784
  Authors
Kiss A, Wang NJ, Xie JP, Thorgeirsson SS
  Title
Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas.
  Journal
Clin Cancer Res 3:1059-66 (1997)
Reference
  Authors
Mamiya T, Yamazaki K, Masugi Y, Mori T, Effendi K, Du W, Hibi T, Tanabe M, Ueda M, Takayama T, Sakamoto M
  Title
Reduced transforming growth factor-beta receptor II expression in hepatocellular carcinoma correlates with intrahepatic metastasis.
  Journal
Lab Invest 90:1339-45 (2010)
DOI:10.1038/labinvest.2010.105
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