KEGG   VARIANT: 7704v1Help
Entry
7704v1                      Variant                                

Name
PLZF-RARA fusion
Gene
ZBTB16  zinc finger and BTB domain containing 16 [KO:K10055]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
translocation t(11;17)(q23;q21)
Network
nt06240  Transcription
nt06275  Acute myeloid leukemia
  Element
N00110  PLZF-RARA fusion to transcriptional activtion
N00114  PLZF-RARA fusion to transcriptional repression
Reference
  Authors
Scandura JM, Boccuni P, Cammenga J, Nimer SD
  Title
Transcription factor fusions in acute leukemia: variations on a theme.
  Journal
Oncogene 21:3422-44 (2002)
DOI:10.1038/sj.onc.1205315
Reference
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
  Authors
Sainty D, Liso V, Cantu-Rajnoldi A, Head D, Mozziconacci MJ, Arnoulet C, Benattar L, Fenu S, Mancini M, Duchayne E, Mahon FX, Gutierrez N, Birg F, Biondi A, Grimwade D, Lafage-Pochitaloff M, Hagemeijer A, Flandrin G
  Title
A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlying PLZF/RARA gene rearrangements.
  Journal
Blood 96:1287-96 (2000)
LinkDB All DBs

DBGET integrated database retrieval system