Entry |
|
Name |
|
Gene |
|
Organism |
hsa_var Human gene variants (Homo sapiens)
|
Variation |
translocation t(3;21)(q26;q22) |
Network |
|
Element |
N00106 | AML1-EVI1 fusion to TGF-beta signaling pathway |
|
Reference |
|
Authors |
Mitani K. |
Title |
Molecular mechanisms of leukemogenesis by AML1/EVI-1. |
Journal |
|
Reference |
|
Authors |
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H. |
Title |
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells. |
Journal |
Blood 92:4003-12 (1998) |
Reference |
|
Authors |
Dong M, Blobe GC. |
Title |
Role of transforming growth factor-beta in hematologic malignancies. |
Journal |
|
LinkDB |
|