| Entry |
|
|---|
| Name |
|
|---|
| Gene |
|
|---|
| Organism |
hsa_var Human gene variants (Homo sapiens)
|
|---|
| Variation |
translocation t(3;21)(q26;q22) |
|---|
| Network |
|
|---|
| Element |
| N00106 | AML1-EVI1 fusion to TGF-beta signaling pathway |
|
|---|
| Reference |
|
|---|
| Authors |
Mitani K. |
|---|
| Title |
Molecular mechanisms of leukemogenesis by AML1/EVI-1. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H. |
|---|
| Title |
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells. |
|---|
| Journal |
Blood 92:4003-12 (1998) |
|---|
| Reference |
|
|---|
| Authors |
Dong M, Blobe GC. |
|---|
| Title |
Role of transforming growth factor-beta in hematologic malignancies. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
