KEGG   VARIANT: 999v3Help
Entry
999v3                      Variant                                 

Name
CDH1 loss
Gene
CDH1  cadherin 1 [KO:K05689]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
Allelic loss on 16q
Network
nt06215  WNT signaling
nt06261  Gastric cancer
  Element
N00257  Loss of CDH1 to beta-catenin signaling pathway
Reference
  Authors
Lee YS, Cho YS, Lee GK, Lee S, Kim YW, Jho S, Kim HM, Hong SH, Hwang JA, Kim SY, Hong D, Choi IJ, Kim BC, Kim BC, Kim CH, Choi H, Kim Y, Kim KW, Kong G, Kim HL, Bhak J, Lee SH, Lee JS
  Title
Genomic profile analysis of diffuse-type gastric cancers.
  Journal
Genome Biol 15:R55 (2014)
DOI:10.1186/gb-2014-15-4-r55
Reference
PMID:8127895
  Authors
Oda T, Kanai Y, Oyama T, Yoshiura K, Shimoyama Y, Birchmeier W, Sugimura T, Hirohashi S
  Title
E-cadherin gene mutations in human gastric carcinoma cell lines.
  Journal
Proc Natl Acad Sci U S A 91:1858-62 (1994)
DOI:10.1073/pnas.91.5.1858
Reference
  Authors
Ascano JJ, Frierson H Jr, Moskaluk CA, Harper JC, Roviello F, Jackson CE, El-Rifai W, Vindigni C, Tosi P, Powell SM
  Title
Inactivation of the E-cadherin gene in sporadic diffuse-type gastric cancer.
  Journal
Mod Pathol 14:942-9 (2001)
DOI:10.1038/modpathol.3880416
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