Halomonas aestuarii: BOX17_01740
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Entry
BOX17_01740 CDS
T04554
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hsi
Halomonas aestuarii
Pathway
hsi00300
Lysine biosynthesis
hsi00550
Peptidoglycan biosynthesis
hsi01100
Metabolic pathways
hsi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hsi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BOX17_01740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BOX17_01740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BOX17_01740
Enzymes [BR:
hsi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BOX17_01740
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
APE29793
UniProt:
A0A1J0VCN6
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Position
complement(396031..397398)
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AA seq
455 aa
AA seq
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MSGVGLQTLHEVADALGLTRPDEDPAVGAIVTDTRKLAPGALFVALRGERFDAHEFVAQA
REAGAVAALVERPVDDPLPQLVVPDTRLALGLLARARRRAWGGALVAVTGNSGKTTVKQM
LATLLGRSGATLATEGNLNNDIGAPLTLLALEPGHRQAVVELGANHLGEIAWTTALAGPR
VAVITNVTGAHVGEFGGMGRIAQAKAEILAGLPDDGVAVLNRDDAFFAAWAGLAAPREVL
DFGLDPRARLRAEALACDALGRYAFTLVRDGREIGRVRLALLGRHNVANALAAAAAALAM
GLEEAEVLAGLEAVAPMTGRMSVVEGLNGTYLLDDTYNANPGAVKAALDVLVTLPAPHWC
LLGAMGELGGESDRLHAELGHYAREQGVDFLGTLGEPARPASQAFGEGGSHFDDREALMR
HVLHHLPPGASVLVKGSRSAGMEHVVAALRADASR
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcgtgggcctgcagacgctgcacgaggtggccgacgccctcgggctgacgcgg
cccgacgaggatccggccgtcggcgccatcgtcaccgatacccggaagctcgcgcccggg
gcgctgttcgtggcgctgcgcggcgagcgcttcgatgcccacgagttcgtggctcaggcc
cgcgaggccggggccgtggcggcgctcgtcgagcggccggtggacgacccgctgccccag
ctggtggtgcccgacacccgtctcgccctggggctgctggcgcgggcgcggcgccgggcc
tggggcggggccctggtcgccgtcaccggcaacagcggcaagactacggtcaagcagatg
ctggcgaccctgctgggccgcagcggggcgacgctcgccaccgagggcaacctcaacaac
gatatcggcgcgcccctgaccctgctggccctcgagccgggccaccgccaggcggtggtg
gagctgggggccaaccacctcggcgagatcgcctggaccacggccctggccggccctcgg
gtggcggtgatcaccaacgtcaccggcgcccacgtgggcgagttcggcggcatgggccgc
atcgcccaggccaaggccgagatcctggccggcctgcccgacgacggcgtggccgtgctc
aatcgcgacgatgccttcttcgcggcctgggcgggcctcgccgcgccgcgggaggtgctc
gacttcgggctggacccgagggcccgccttcgggccgaggcgctggcctgcgacgccctt
gggcgctatgctttcacgcttgttcgggacggccgcgagatcggccgggtgcggttggcc
ctgctggggcgtcacaacgtggccaatgccctggccgccgccgcggcggcgctggccatg
ggactcgaggaggccgaggtgctggccggactcgaggcggtggcgccgatgacgggccgg
atgagcgtcgtggaaggcctcaacggcacgtacctgctggacgatacctataatgccaac
cccggcgcggtgaaggcggcgctcgatgtcctcgtgacgctgccggcaccgcactggtgc
ctgctcggcgccatgggagaactgggaggcgagtccgaccggctgcatgccgagctcggg
cactacgcgcgggaacagggggtcgattttctgggtaccctcggcgagccggcacggccg
gccagccaggccttcggcgaaggcgggtcccatttcgacgaccgggaggcgctgatgcgc
cacgtcctccaccatctaccgcccggggccagcgtgctggtcaagggttcgcgcagtgcc
ggcatggaacacgtcgttgccgccctgcgcgcggatgcttcaaggtga
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