KEGG   ORTHOLOGY: K00209
Entry
K00209                      KO                                     

Name
fabV, ter
Definition
enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]
Pathway
ko00061  Fatty acid biosynthesis
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
ko01212  Fatty acid metabolism
Module
M00083  Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.9  enoyl-[acyl-carrier-protein] reductase (NADH)
     K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
    1.3.1.44  trans-2-enoyl-CoA reductase (NAD+)
     K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
Other DBs
RN: R01171 R01403 R04429 R04724 R04955 R04958 R04961 R04966 R04969
COG: COG3007
GO: 0004318 0050343
Genes
ECLI: ECNIH5_17550
ECLA: ECNIH3_17630
ECLC: ECR091_17565
ECHG: FY206_20085
ENR: H650_03745
KOM: HR38_29650
KLL: BJF97_31980
CFD: CFNIH1_03990
CBRA: A6J81_16945
CYO: CD187_23885
KAS: KATP_43710(fabV)
YPE: YPO4104
YPK: y4119
YPH: YPC_4625
YPA: YPA_4149
YPN: YPN_3961
YPM: YP_4011
YPZ: YPZ3_3519
YPD: YPD4_3612
YPX: YPD8_3618
YPW: CH59_2061
YPJ: CH55_2786
YPV: BZ15_3598
YPL: CH46_944
YPS: YPTB3950
YPO: BZ17_2626
YPY: YPK_4244
YPB: YPTS_4200
YPQ: DJ40_2454
YPU: BZ21_3312
YPR: BZ20_2152
YPC: BZ23_3584
YPF: BZ19_3421
YEN: YE4179
YEY: Y11_29991
YEW: CH47_3544
YET: CH48_1641
YAL: AT01_2511
YFR: AW19_3288
YIN: CH53_1737
YKR: CH54_2502
YRO: CH64_2556
SMAR: SM39_1424
SPE: Spro_1949
SPLY: Q5A_009815
SSZ: SCc_447(fadH)
SMAF: D781_2172
SERF: L085_18945
RAA: Q7S_24276
EAM: EAMY_1757
EAY: EAM_1724
ETA: ETA_17430
EPY: EpC_18330
EBI: EbC_22580
EHD: ERCIPSTX3056_499(fabV)
ERWI: GN242_09860(fabV)
MMK: MU9_3082
ETR: ETAE_1876
ETD: ETAF_1690
ETE: ETEE_3920
XFA: XF_1835
XFT: PD_1032
XCC: XCC0115
XCB: XC_0119
XCP: XCR_0135
XCV: XCV0120
XAX: XACM_0118
XAC: XAC0141
XOM: XOO0026(XOO0026)
XOO: XOO0027
XOP: PXO_03458
XOR: XOC_0167
XAL: XALC_0021
XPH: XppCFBP6546_11220(XppCFBP6546P_11220)
SML: Smlt2015
SMT: Smal_1619
SMZ: SMD_1813
PSUW: WQ53_10060
PSD: DSC_01770
LEZ: GLE_0533
LEM: LEN_4374(fabI)
DKO: I596_2167
RBD: ALSL_1666
VCH: VCA0784
VTA: A0307 B1745
VAS: GT360_09710(fabV) GT360_17275(fabV)
VFI: VF_0888
PPR: PBPRA2423(PD1032) PBPRA2527(XCC0115)
PAE: PA2950
PAEV: N297_3055
PAEI: N296_3055
PAEP: PA1S_10645
PAEM: U769_10185
PAEL: T223_10660
PAEG: AI22_23225
PAEC: M802_3052
PAEO: M801_2920
PPU: PP_4635
PPF: Pput_4497
PPT: PPS_4463
PPI: YSA_03207
PPX: T1E_1542
PPUH: B479_22445
PPUT: L483_27635
PPUN: PP4_07240
PPUD: DW66_4854
PMON: X969_21985
PMOT: X970_21620
PFL: PFL_3335
PPRO: PPC_3359
PFS: PFLU_1621
PFB: VO64_4743
PEN: PSEEN4627
PSEM: TO66_13430
PSOS: POS17_2731
PANR: A7J50_1779
POJ: PtoMrB4_10190(fabV)
SON: SO_1800(fabV)
SDN: Sden_2487
SFR: Sfri_2585
SAZ: Sama_1230
SBL: Sbal_1610
SLO: Shew_2503
SPL: Spea_2676
SWD: Swoo_3107
SWP: swp_3256
SVO: SVI_2991
SPSW: Sps_01876
ILO: IL1051
CPS: CPS_0713
PHA: PSHAa2242
PTN: PTRA_a2718(fabV)
PAT: Patl_0451
PSM: PSM_A0844
PSEO: OM33_14400
PEA: PESP_a1049(fabV)
PSPO: PSPO_a2425(fabV)
PART: PARC_a2990(fabV)
PTU: PTUN_a3293(fabV)
PNG: PNIG_a2914(fabV)
PTD: PTET_a0957(fabV)
PAGA: PAGA_a2864(fabV)
AMAL: I607_16415
AMAE: I876_16720
AMAO: I634_16670
AMAD: I636_16595
AMAI: I635_17340
AMAG: I533_16250
AMAC: MASE_16235
AAUS: EP12_16965
ASP: AOR13_51
GNI: GNIT_0762
GPS: C427_0467
SALH: HMF8227_00458(fabV)
PIN: Ping_0610
FBL: Fbal_2593
MVS: MVIS_2342
MYA: MORIYA_0893(fabV)
CJA: CJA_1411
SDE: Sde_2625
SAGA: M5M_18710
MHYD: GTQ55_13585(fabV)
CBU: CBU_0270
CBD: CBUD_1824
CBG: CbuG_1738
CBC: CbuK_0462
LFA: LFA_0887
METL: U737_06065
CYQ: Q91_0539
CSA: Csal_2823
HEL: HELO_1411(fabV)
HAM: HALO1431
HBE: BEI_0481(fabV)
KKO: Kkor_0610
KGE: TQ33_1781
BMAR: HF888_09690(fabV)
ACAV: VI35_00235
TAU: Tola_2687
OCE: GU3_06675
BMA: BMA0885
BMAL: DM55_2100
BMAE: DM78_2182
BMAQ: DM76_2075
BMAI: DM57_2939
BMAF: DM51_638
BMAZ: BM44_2366
BMAB: BM45_1931
BPS: BPSL2019
BPSE: BDL_555
BPSM: BBQ_1890
BPSU: BBN_2016
BPSD: BBX_2494
BPK: BBK_66
BPSH: DR55_3131
BPSA: BBU_725
BPSO: X996_2745
BUT: X994_1198
BTE: BTH_I2672
BTQ: BTQ_1352
BTJ: BTJ_1100
BTZ: BTL_2341
BTD: BTI_2416
BTV: BTHA_2540
BTHE: BTN_2427
BTHM: BTRA_2621
BTHA: DR62_2572
BTHL: BG87_2565
BOK: DM82_919
BOC: BG90_16
BVE: AK36_3125
BCN: Bcen_5407
BCJ: BCAM2650
BCEN: DM39_5213
BCEW: DM40_3246
BCEO: I35_6544
BAM: Bamb_4797
BMU: Bmul_3324
BMK: DM80_4705
BMUL: NP80_3219
BCT: GEM_5745
BCED: DM42_5327
BDL: AK34_3233
BCON: NL30_17025
BUB: BW23_3838
BLAT: WK25_28815
BTEI: WS51_09975
BSEM: WJ12_33150
BPSL: WS57_01055
BMEC: WJ16_31620
BSTG: WT74_31895
BGU: KS03_3964
BGO: BM43_6471
BUK: MYA_3271
BUL: BW21_2383
BXE: Bxe_A2198
BXB: DR64_4351
BFN: OI25_3615
PPNO: DA70_23345
PPNM: LV28_07365
PPUL: RO07_01555
PSPU: NA29_10105
PAPI: SG18_01690
PFIB: PI93_010265(fabV)
CABA: SBC2_44980(fabV)
MFA: Mfla_1676
SCL: sce6077
SECH: B18_27720
PPO: PPM_1661(M1_1918) PPM_3737(M1_4127)
PRI: PRIO_5321
PBK: Back11_45430(fabV)
COHN: KCTCHS21_04210(fabV)
LBR: LVIS_0246
LHO: LOOC260_120310(ter)
PCE: PECL_1363
CARC: NY10_1787
CARN: FPV25_05955(fabV)
JDA: BW727_101649(fabV)
CAC: CA_C0462
CAE: SMB_G0472
CAY: CEA_G0473
CPE: CPE2074
CPF: CPF_2331
CPR: CPR_2045
CBE: Cbei_2086
CBZ: Cbs_2086
CBEI: LF65_02396
CPAS: Clopa_3224
CPAT: CLPA_c16150(ccel)
CPAE: CPAST_c16150(ccel)
CCE: Ccel_2273
CCEL: CCDG5_1162
COO: CCU_20510
BPRO: PMF13cell1_03010(fabV)
CPY: Cphy_1286
BPRL: CL2_10840
CBAR: PATL70BA_3140(fabV)
MHG: MHY_09170
PFT: JBW_04265
ACL: ACL_0420
SALU: DC74_5018
SALL: SAZ_26790
STRE: GZL_03844
STRM: M444_26220
SRW: TUE45_pSRc_0278(TUE45_pSRTUE45c_0278)
SLAU: SLA_7515
SFK: KY5_6735
SVN: CP980_31775(fabV)
STRI: C7M71_007285(fabV)
KFL: Kfla_5038
KQI: F1D05_07525(fabV)
MICH: FJK98_03885(fabV)
OTE: Oter_3891
CAA: Caka_1566
TDE: TDE0597
TPED: TPE_2028
BRM: Bmur_1267
BPW: WESB_2159
BIP: Bint_2694
LBA: Lebu_0716
LWD: JCM16777_1291(fabV)
FSC: FSU_1176
FLN: FLA_3939
PHE: Phep_2275
SPHE: GFH32_07715(fabV)
CHU: CHU_1071
FLM: MY04_3863
CHE: CAHE_0279
CEC: CE557_333
CHER: DK880_00627(fabV)
FPS: FP1842
FJO: Fjoh_3464
FIN: KQS_09375
FSN: GS03_01917(fabV)
MPW: MPR_2757
WIN: WPG_3437
TMAR: MARIT_1974
AALG: AREALGSMS7_00271(fabV)
EAO: BD94_2940
AG: AAW66853(ter)
 » show all
Reference
  Authors
Massengo-Tiasse RP, Cronan JE
  Title
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase.
  Journal
J Biol Chem 283:1308-16 (2008)
DOI:10.1074/jbc.M708171200
Reference
  Authors
Lu H, Tonge PJ
  Title
Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei.
  Journal
Biochemistry 49:1281-9 (2010)
DOI:10.1021/bi902001a
Reference
  Authors
Hoffmeister M, Piotrowski M, Nowitzki U, Martin W
  Title
Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis.
  Journal
J Biol Chem 280:4329-38 (2005)
DOI:10.1074/jbc.M411010200
  Sequence
Reference
  Authors
Tucci S, Martin W
  Title
A novel prokaryotic trans-2-enoyl-CoA reductase from the spirochete Treponema denticola.
  Journal
FEBS Lett 581:1561-6 (2007)
DOI:10.1016/j.febslet.2007.03.013
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