KEGG   ORTHOLOGY: K00408Help
Entry
K00408                      KO                                     

Name
WNT4
Definition
wingless-type MMTV integration site family, member 4
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04919  Thyroid hormone signaling pathway
ko04934  Cushing syndrome
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00600  Mullerian agenesis
H02317  SERKAL syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04390 Hippo signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04150 mTOR signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04916 Melanogenesis
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09158 Development and regeneration
   04360 Axon guidance
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05205 Proteoglycans in cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05226 Gastric cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05217 Basal cell carcinoma
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05224 Breast cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00408  WNT4; wingless-type MMTV integration site family, member 4
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Morphogens
   K00408  WNT4; wingless-type MMTV integration site family, member 4
BRITE hierarchy
Genes
HSA: 54361(WNT4)
PTR: 469212(WNT4)
PPS: 100992168(WNT4)
GGO: 101139722(WNT4)
PON: 100436330(WNT4)
NLE: 100604353(WNT4)
MCC: 707864(WNT4)
MCF: 102143058(WNT4)
CSAB: 103225420(WNT4)
RRO: 104663222(WNT4)
RBB: 108538467(WNT4)
CJC: 100387135(WNT4)
SBQ: 101050255(WNT4)
MMU: 22417(Wnt4)
MCAL: 110293218(Wnt4)
MPAH: 110323343(Wnt4)
RNO: 84426(Wnt4)
MUN: 110545007(Wnt4)
CGE: 100769003(Wnt4)
NGI: 103746395(Wnt4)
HGL: 101701972(Wnt4)
CCAN: 109694918(Wnt4)
OCU: 100303773(WNT4)
TUP: 102493340(WNT4)
CFA: 612367(WNT4)
VVP: 112929848(WNT4)
AML: 100468584(WNT4)
UMR: 103666795(WNT4)
UAH: 113268542(WNT4)
ORO: 101365138(WNT4)
ELK: 111154909
FCA: 101095185(WNT4)
PPAD: 109274277(WNT4)
AJU: 113599491(WNT4)
BTA: 789600(WNT4)
BOM: 102269858(WNT4)
BIU: 109576138(WNT4)
BBUB: 102405649(WNT4)
CHX: 102187819(WNT4)
OAS: 101122423(WNT4)
SSC: 100327037(WNT4)
CFR: 102522577(WNT4)
CDK: 105088869(WNT4)
BACU: 103009300(WNT4)
LVE: 103087836(WNT4)
OOR: 101270876(WNT4)
DLE: 111163319(WNT4)
PCAD: 102975662(WNT4)
ECB: 100071678(WNT4)
EPZ: 103558485(WNT4)
EAI: 106840003(WNT4)
MYB: 102240589(WNT4)
MYD: 102756007(WNT4)
MNA: 107538446(WNT4)
HAI: 109396735(WNT4)
DRO: 112299558(WNT4)
PALE: 102888866(WNT4)
RAY: 107513057(WNT4)
MJV: 108391532(WNT4)
LAV: 100664388(WNT4)
TMU: 101361433
MDO: 100026048(WNT4)
SHR: 100925510(WNT4)
PCW: 110206034(WNT4)
OAA: 100075238(WNT4)
GGA: 395561(WNT4)
MGP: 100547391(WNT4)
CJO: 107323388(WNT4)
NMEL: 110408700(WNT4)
APLA: 101791711(WNT4) 101793827
ACYG: 106047829 106049157(WNT4)
TGU: 100230804(WNT4)
LSR: 110472242(WNT4) 110480808
SCAN: 103812459 103824161(WNT4)
GFR: 102040060(WNT4) 106631805
FAB: 101806519(WNT4)
PHI: 102106062(WNT4) 102113442
PMAJ: 107212798 107213785(WNT4)
CCAE: 111938570(WNT4)
CCW: 104687219 104697541(WNT4)
ETL: 114066847(WNT4)
FPG: 101918156 101922779(WNT4)
FCH: 102048943(WNT4) 102056989
CLV: 102083488 102098373(WNT4)
EGZ: 104126592 104131863(WNT4)
NNI: 104009660 104011200(WNT4)
ACUN: 113486790 113487831(WNT4)
AAM: 106497177 106498597(WNT4)
ASN: 102367890 102376031(WNT4)
AMJ: 102561676(WNT4) 102573669
PSS: 102450128(WNT4) 102455801
CMY: 102931707 102945642(WNT4)
CPIC: 101941332(WNT4) 101944542
ACS: 100567689(wnt4)
PVT: 110086828(WNT4)
PBI: 103054356(WNT4)
PMUR: 107290018(WNT4)
TSR: 106554369(WNT4)
PMUA: 114588116 114602590(WNT4)
XLA: 108697659 397706(wnt4.S)
XTR: 100491282(wnt4)
NPR: 108797396(WNT4)
DRE: 30123(wnt4)
IPU: 108255178(wnt4) 108263562
PHYP: 113525149 113538116(wnt4)
AMEX: 103021666 103046581(wnt4)
EEE: 113574764 113586658(wnt4)
TRU: 101067916 101068089(wnt4)
LCO: 104923622(wnt4) 104932544
MZE: 101473265(wnt4) 101479331
ONL: 100691883(wnt4) 100712297
OLA: 100301590(wnt4) 100301591(wnt4b)
XMA: 102232798(wnt4) 102236316
XCO: 114136002(wnt4) 114139694
PRET: 103465422(wnt4) 103477994
CVG: 107082204 107085099(wnt4)
NFU: 107374130(wnt4) 107379462
KMR: 108235425 108248640(wnt4)
ALIM: 106528517(wnt4) 106529149
AOCE: 111573832(wnt4) 111585705
CSEM: 103386287(wnt4) 103388020
POV: 109629351(wnt4) 109643472
LCF: 108877528(wnt4) 108880750
SDU: 111221581(wnt4) 111230085
SLAL: 111668597(wnt4) 111669912
HCQ: 109515380 109521622(wnt4)
BPEC: 110163101 110165764(wnt4)
MALB: 109966188 109971989(wnt4)
ELS: 105025459(wnt4) 105029960
LCM: 102358331(WNT4) 102366334
CMK: 103181434(wnt4)
SPU: 100892060
APLC: 110984610
SKO: 100329013(Wnt4)
BMOR: 101735411
BMAN: 114243804
HAW: 110381010
API: 100164094
DNX: 107168857
BTAB: 109042201
CLEC: 106671088
TUT: 107361270
CEL: CELE_F38E1.7(mom-2) CELE_K10B4.6(cwn-1)
CBR: CBG11282(Cbr-mom-2)
PCAN: 112557635
CRG: 105343129
MYI: 110451002
OBI: 106874406
SHX: MS3_03642
EGL: EGR_03061
PDAM: 113684198
SPIS: 111338419
DGT: 114518043
AQU: 100641115(Wnt)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bernardi H, Gay S, Fedon Y, Vernus B, Bonnieu A, Bacou F
  Title
Wnt4 activates the canonical beta-catenin pathway and regulates negatively myostatin: functional implication in myogenesis.
  Journal
Am J Physiol Cell Physiol 300:C1122-38 (2011)
DOI:10.1152/ajpcell.00214.2010
Reference
  Authors
Saulnier DM, Ghanbari H, Brandli AW
  Title
Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.
  Journal
Dev Biol 248:13-28 (2002)
DOI:10.1006/dbio.2002.0712
  Sequence
[xla:397706]
Reference
  Authors
Jordan BK, Mohammed M, Ching ST, Delot E, Chen XN, Dewing P, Swain A, Rao PN, Elejalde BR, Vilain E
  Title
Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.
  Journal
Am J Hum Genet 68:1102-9 (2001)
DOI:10.1086/320125
  Sequence
[hsa:54361]
LinkDB All DBs

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