KEGG   ORTHOLOGY: K01831
Entry
K01831                      KO                                     

Name
PTGIS, CYP8A
Definition
prostacyclin synthase [EC:5.3.99.4]
Pathway
ko00590  Arachidonic acid metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K01831  PTGIS, CYP8A; prostacyclin synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K01831  PTGIS, CYP8A; prostacyclin synthase
Enzymes [BR:ko01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.4  prostaglandin-I synthase
     K01831  PTGIS, CYP8A; prostacyclin synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP8 family
   K01831  PTGIS, CYP8A; prostacyclin synthase
Other DBs
RN: R02267
GO: 0008116
Genes
HSA: 5740(PTGIS)
PTR: 458323(PTGIS)
PPS: 100987973(PTGIS)
GGO: 101132214(PTGIS)
PON: 100440673(PTGIS)
NLE: 100592236(PTGIS)
MCC: 703407(PTGIS)
MCF: 102123511(PTGIS)
CSAB: 103244560(PTGIS)
RRO: 104678532(PTGIS)
RBB: 108539469(PTGIS)
CJC: 100403062(PTGIS)
SBQ: 101034236(PTGIS)
MMU: 19223(Ptgis)
MCAL: 110289735(Ptgis)
MPAH: 110318865(Ptgis)
RNO: 25527(Ptgis)
MUN: 110549006(Ptgis)
CGE: 100757024(Ptgis)
NGI: 103735556(Ptgis)
HGL: 101700601(Ptgis)
CCAN: 109690523(Ptgis)
OCU: 103346149
TUP: 102496170(PTGIS)
CFA: 100856661(PTGIS)
VVP: 112931895(PTGIS)
AML: 100466540(PTGIS)
UMR: 103669841(PTGIS)
UAH: 113258701(PTGIS)
ORO: 101382580(PTGIS)
ELK: 111141584
FCA: 101082050(PTGIS)
PTG: 102952139(PTGIS)
PPAD: 109272209(PTGIS)
AJU: 106986024(PTGIS)
BTA: 282021(PTGIS)
BOM: 102279286(PTGIS)
BIU: 109567538
BBUB: 102391623(PTGIS)
CHX: 100860894(PTGIS)
OAS: 101116418(PTGIS)
SSC: 100126284(PTGIS)
CFR: 102521764(PTGIS)
CDK: 105087868(PTGIS)
BACU: 103018962(PTGIS)
LVE: 103069768(PTGIS)
OOR: 101285307(PTGIS)
DLE: 111186649(PTGIS) 111187839
PCAD: 102985868 114483838(PTGIS)
ECB: 100071412(PTGIS)
EPZ: 103541173(PTGIS)
EAI: 106825769(PTGIS)
MYB: 102249227(PTGIS)
MYD: 102772939(PTGIS)
MNA: 107540608(PTGIS)
HAI: 109381877(PTGIS)
DRO: 112303771(PTGIS)
PALE: 102885283(PTGIS)
RAY: 107510328(PTGIS)
MJV: 108391976(PTGIS)
LAV: 100669854(PTGIS)
TMU: 101360898
MDO: 100029131(PTGIS)
SHR: 100924178(PTGIS)
PCW: 110206638(PTGIS)
OAA: 100076102(PTGIS)
ASN: 102380148(PTGIS)
AMJ: 102570396(PTGIS)
PSS: 102459815(PTGIS)
CMY: 102929462(PTGIS)
CPIC: 101948711(PTGIS)
ACS: 100565699(ptgis)
PVT: 110071794(PTGIS)
PBI: 103056719(PTGIS)
PMUR: 107290825(PTGIS)
TSR: 106539549(PTGIS)
PMUA: 114599622(PTGIS)
GJA: 107122715
XLA: 108700877(ptgis.L)
XTR: 100492372(ptgis)
NPR: 108803621
DRE: 559148(ptgis)
SGH: 107555969 107561003(ptgis)
IPU: 108271893 108272147(ptgis)
LCO: 104920521 104928129(ptgis)
OLA: 101170919(ptgis)
CVG: 107093334 107096113(ptgis)
KMR: 108231375(ptgis) 108235780
ALIM: 106516065 106517980(ptgis)
CSEM: 103385737 103385896(ptgis)
POV: 109629045(ptgis) 109638533
LCF: 108889866(ptgis)
SDU: 111222105(ptgis) 111222893
SLAL: 111657863 111660836(ptgis)
BPEC: 110168753 110168791(ptgis)
MALB: 109964506(ptgis)
ELS: 105017022(ptgis) 105026471
SFM: 108923412 108939002(ptgis)
PKI: 111833099 111840521(ptgis)
LCM: 102358660(PTGIS)
CMK: 103190529(ptgis)
RTP: 109914197
 » show all
Reference
PMID:8185632
  Authors
Miyata A, Hara S, Yokoyama C, Inoue H, Ullrich V, Tanabe T
  Title
Molecular cloning and expression of human prostacyclin synthase.
  Journal
Biochem Biophys Res Commun 200:1728-34 (1994)
DOI:10.1006/bbrc.1994.1652
  Sequence
[hsa:5740]
Reference
PMID:9202154
  Authors
Kuwamoto S, Inoue H, Tone Y, Izumi Y, Tanabe T
  Title
Inverse gene expression of prostacyclin and thromboxane synthases in resident and activated peritoneal macrophages.
  Journal
FEBS Lett 409:242-6 (1997)
DOI:10.1016/S0014-5793(97)00516-4
  Sequence
[mmu:19223]
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