KEGG   ORTHOLOGY: K02620
Entry
K02620                      KO                                     

Name
TCF7, TCF-1
Definition
transcription factor 7
Pathway
map04310  Wnt signaling pathway
map04390  Hippo signaling pathway
map04520  Adherens junction
map04550  Signaling pathways regulating pluripotency of stem cells
map04916  Melanogenesis
map04934  Cushing syndrome
map05132  Salmonella infection
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05213  Endometrial cancer
map05215  Prostate cancer
map05216  Thyroid cancer
map05217  Basal cell carcinoma
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
   04390 Hippo signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K02620  TCF7, TCF-1; transcription factor 7
   04550 Signaling pathways regulating pluripotency of stem cells
    K02620  TCF7, TCF-1; transcription factor 7
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K02620  TCF7, TCF-1; transcription factor 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05225 Hepatocellular carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05226 Gastric cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05216 Thyroid cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05221 Acute myeloid leukemia
    K02620  TCF7, TCF-1; transcription factor 7
   05217 Basal cell carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05215 Prostate cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05213 Endometrial cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05224 Breast cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02620  TCF7, TCF-1; transcription factor 7
   05165 Human papillomavirus infection
    K02620  TCF7, TCF-1; transcription factor 7
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K02620  TCF7, TCF-1; transcription factor 7
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K02620  TCF7, TCF-1; transcription factor 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K02620  TCF7, TCF-1; transcription factor 7
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02620  TCF7, TCF-1; transcription factor 7
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K02620  TCF7, TCF-1; transcription factor 7
Genes
HSA: 6932(TCF7)
PTR: 745839(TCF7)
PPS: 100980839(TCF7)
GGO: 101149731(TCF7)
PON: 100461234(TCF7)
NLE: 100595737(TCF7)
MCC: 710234(TCF7)
MCF: 102142248(TCF7)
CSAB: 103244543(TCF7)
CATY: 105599768(TCF7)
PANU: 101024089(TCF7)
RRO: 104659811(TCF7)
RBB: 108529562(TCF7)
TFN: 117065864(TCF7)
PTEH: 111529175(TCF7)
CJC: 100399154(TCF7)
SBQ: 101029076(TCF7)
MMUR: 105869975(TCF7)
MMU: 21414(Tcf7)
MCAL: 110304948(Tcf7)
MPAH: 110332085(Tcf7)
RNO: 363595(Tcf7)
MCOC: 116077224(Tcf7)
MUN: 110549622(Tcf7)
CGE: 100757390(Tcf7)
PLEU: 114683055(Tcf7)
NGI: 103729786(Tcf7)
HGL: 101707882(Tcf7)
CCAN: 109689465(Tcf7)
OCU: 100339216(TCF7)
TUP: 102484318(TCF7)
CFA: 481506(TCF7)
VVP: 112917059(TCF7)
VLG: 121495797(TCF7)
AML: 100476528(TCF7)
UMR: 103663815(TCF7)
UAH: 113261735(TCF7)
ORO: 101376237(TCF7)
ELK: 111141244
MPUF: 101678117(TCF7)
EJU: 114209512(TCF7)
MLX: 118016638(TCF7)
FCA: 101098768(TCF7)
PTG: 102957988(TCF7)
PPAD: 109250863(TCF7)
AJU: 106984911(TCF7)
HHV: 120238500(TCF7)
BTA: 782690(TCF7)
BOM: 102266633(TCF7)
BIU: 109562015(TCF7)
BBUB: 102408996(TCF7)
CHX: 102173736(TCF7)
OAS: 101101980(TCF7)
ODA: 120863661(TCF7)
SSC: 100512951(TCF7)
CFR: 102519063(TCF7)
CDK: 105090254(TCF7)
BACU: 103018264(TCF7)
LVE: 103074150(TCF7)
OOR: 101289599(TCF7)
DLE: 111182442(TCF7)
PCAD: 102992878(TCF7)
ECB: 100072786(TCF7)
EPZ: 103543120(TCF7)
EAI: 106834657(TCF7)
MYB: 102250528(TCF7)
MYD: 102757003(TCF7)
MMYO: 118657631(TCF7)
MNA: 107525397(TCF7)
HAI: 109382635(TCF7)
DRO: 112318180(TCF7)
SHON: 118990084(TCF7)
AJM: 119037608(TCF7)
MMF: 118643629(TCF7)
PALE: 102885788(TCF7)
RAY: 107506797(TCF7)
MJV: 108406081(TCF7)
TOD: 119243471(TCF7)
LAV: 100663559(TCF7)
TMU: 101350837
MDO: 100017589(TCF7)
SHR: 100930141(TCF7)
PCW: 110211723(TCF7)
OAA: 100082332(TCF7)
GGA: 395229(TCF7)
PCOC: 116232216(TCF7)
MGP: 100544924(TCF7)
CJO: 107320225(TCF7)
NMEL: 110405287(TCF7)
APLA: 101803610(TCF7)
ACYG: 106032766(TCF7)
TGU: 100221008(TCF7)
LSR: 110481074(TCF7)
SCAN: 103817470(TCF7)
PMOA: 120498623(TCF7)
GFR: 102036749(TCF7)
FAB: 101820491(TCF7)
PHI: 102110510(TCF7)
PMAJ: 107210639(TCF7)
CCAE: 111935599(TCF7)
CCW: 104683724(TCF7)
ETL: 114063910(TCF7)
FPG: 101919678(TCF7)
FCH: 102058554(TCF7)
CLV: 102094656(TCF7)
EGZ: 104133478(TCF7)
NNI: 104012004(TCF7)
ACUN: 113485114(TCF7)
PADL: 103915850(TCF7)
AAM: 106487174(TCF7)
ASN: 102383175(TCF7)
AMJ: 102576120(TCF7)
CPOO: 109310088(TCF7)
GGN: 109289961(TCF7)
PSS: 102446665(TCF7)
CMY: 102943166(TCF7)
CPIC: 101937399(TCF7)
TST: 117882270(TCF7)
CABI: 116826639(TCF7)
ACS: 100554608(tcf7)
PVT: 110079405(TCF7)
PBI: 103067042(TCF7)
PMUR: 107294908(TCF7)
TSR: 106542632(TCF7)
PGUT: 117656083(TCF7)
PMUA: 114591268(TCF7)
ZVI: 118080356(TCF7)
GJA: 107125983(TCF7)
XLA: 398658(tcf7.S)
XTR: 395061(tcf7)
NPR: 108792126(TCF7)
DRE: 497649(tcf7)
SRX: 107728269 107742437(tcf7)
SANH: 107661683(tcf7) 107692971
CCAR: 109048020
IPU: 108278866(tcf7)
PHYP: 113535749
AMEX: 103045826
EEE: 113578029(tcf7)
TRU: 101076516(tcf7)
LCO: 104924428
NCC: 104960861(tcf7)
ELY: 117245747 117268549(tcf7)
PLEP: 121952129(tcf7)
SLUC: 116055911(tcf7) 118493643
ECRA: 117955094(tcf7)
PFLV: 114566424(tcf7)
GAT: 120810826 120821561(tcf7)
MSAM: 119895287(tcf7)
CUD: 121518698(tcf7)
MZE: 101469770(tcf7)
ONL: 100710520(tcf7)
OAU: 116315805(tcf7)
OML: 112137216 112142310(tcf7)
XMA: 102221228(tcf7) 111610761
XCO: 114152465(tcf7) 114157642
XHE: 116728111(tcf7) 116732626
PRET: 103460015(tcf7) 103480959
CVG: 107085909(tcf7)
CTUL: 119797145 119797952(tcf7)
NFU: 107378492 107386837(tcf7)
KMR: 108238102(tcf7)
ALIM: 106524564(tcf7) 106532889
AOCE: 111566135
CSEM: 103394864(tcf7)
POV: 109635808(tcf7)
LCF: 108893669(tcf7)
SDU: 111234495(tcf7)
SLAL: 111659992(tcf7)
XGL: 120803038(tcf7)
MALB: 109966812(tcf7)
OMY: 101268913(tcf7) 110537729
ELS: 105026693
PKI: 111839551
LOC: 102694215(tcf7)
LCM: 102350321(TCF7)
CMK: 103183678(tcf7)
RTP: 109912241
ACER: 108000102
APLN: 108741021
VDE: 111250602
CBR: CBG11789
GAE: 121391070
MYI: 110453946
ATEN: 116297634
 » show all
Reference
PMID:1569101
  Authors
van de Wetering M, Oosterwegel M, Holstege F, Dooyes D, Suijkerbuijk R, Geurts van Kessel A, Clevers H
  Title
The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.
  Journal
J Biol Chem 267:8530-6 (1992)
  Sequence
[hsa:6932]
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056
Reference
  Authors
Ioannidis V, Beermann F, Clevers H, Held W
  Title
The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.
  Journal
Nat Immunol 2:691-7 (2001)
DOI:10.1038/90623
  Sequence
[mmu:21414]
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