KEGG   ORTHOLOGY: K02620Help
Entry
K02620                      KO                                     

Name
TCF7, TCF-1
Definition
transcription factor 7
Pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04520  Adherens junction
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05213  Endometrial cancer
ko05215  Prostate cancer
ko05216  Thyroid cancer
ko05217  Basal cell carcinoma
ko05221  Acute myeloid leukemia
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
   04390 Hippo signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K02620  TCF7, TCF-1; transcription factor 7
   04550 Signaling pathways regulating pluripotency of stem cells
    K02620  TCF7, TCF-1; transcription factor 7
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K02620  TCF7, TCF-1; transcription factor 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05225 Hepatocellular carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05226 Gastric cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05216 Thyroid cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05221 Acute myeloid leukemia
    K02620  TCF7, TCF-1; transcription factor 7
   05217 Basal cell carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05215 Prostate cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05213 Endometrial cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05224 Breast cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K02620  TCF7, TCF-1; transcription factor 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K02620  TCF7, TCF-1; transcription factor 7
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K02620  TCF7, TCF-1; transcription factor 7
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02620  TCF7, TCF-1; transcription factor 7
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K02620  TCF7, TCF-1; transcription factor 7
BRITE hierarchy
Genes
HSA: 6932(TCF7)
PTR: 745839(TCF7)
PPS: 100980839(TCF7)
GGO: 101149731(TCF7)
PON: 100461234(TCF7)
NLE: 100595737(TCF7)
MCC: 710234(TCF7)
MCF: 102142248(TCF7)
CSAB: 103244543(TCF7)
RRO: 104659811(TCF7)
RBB: 108529562(TCF7)
CJC: 100399154(TCF7)
SBQ: 101029076(TCF7)
MMU: 21414(Tcf7)
MCAL: 110304948(Tcf7)
MPAH: 110332085(Tcf7)
RNO: 363595(Tcf7)
MUN: 110549622(Tcf7)
CGE: 100757390(Tcf7)
NGI: 103729786(Tcf7)
HGL: 101707882(Tcf7)
CCAN: 109689465(Tcf7)
OCU: 100339216(TCF7)
TUP: 102484318(TCF7)
CFA: 481506(TCF7)
VVP: 112907824 112917059(TCF7)
AML: 100476528(TCF7)
UMR: 103663815(TCF7)
UAH: 113261735(TCF7)
ORO: 101376237(TCF7)
FCA: 101098768(TCF7)
PTG: 102957988(TCF7)
AJU: 106984911(TCF7)
BTA: 782690(TCF7)
BOM: 102266633(TCF7)
BIU: 109562015(TCF7)
BBUB: 102408996(TCF7)
PHD: 102338430(TCF7)
CHX: 102173736(TCF7)
OAS: 101101980(TCF7)
SSC: 100512951(TCF7)
CFR: 102519063(TCF7)
CDK: 105090254(TCF7)
BACU: 103018264(TCF7)
LVE: 103074150(TCF7)
OOR: 101289599(TCF7)
DLE: 111182442(TCF7)
PCAD: 102992878(TCF7)
ECB: 100072786(TCF7)
EPZ: 103543120(TCF7)
EAI: 106834657(TCF7)
MYB: 102250528(TCF7)
MYD: 102757003(TCF7)
MNA: 107525397(TCF7)
HAI: 109382635(TCF7)
RSS: 109451821(TCF7)
DRO: 112318180(TCF7)
PALE: 102885788(TCF7)
RAY: 107506797(TCF7)
LAV: 100663559(TCF7)
TMU: 101350837
MDO: 100017589(TCF7)
SHR: 100930141(TCF7)
PCW: 110211723(TCF7)
OAA: 100082332(TCF7)
GGA: 395229(TCF7)
MGP: 100544924(TCF7)
CJO: 107320225(TCF7)
NMEL: 110405287(TCF7)
APLA: 101803610(TCF7)
ACYG: 106032766(TCF7)
TGU: 100221008(TCF7)
LSR: 110481074(TCF7)
SCAN: 103817470(TCF7)
GFR: 102036749(TCF7)
FAB: 101820491(TCF7)
PHI: 102110510(TCF7)
PMAJ: 107210639(TCF7)
CCAE: 111935599(TCF7)
CCW: 104683724(TCF7)
ETL: 114063910(TCF7)
FPG: 101919678(TCF7)
FCH: 102058554(TCF7)
CLV: 102094656(TCF7)
EGZ: 104133478(TCF7)
NNI: 104012004(TCF7)
ACUN: 113485114(TCF7)
PADL: 103915850(TCF7)
AAM: 106487174(TCF7)
ASN: 102383175(TCF7)
AMJ: 102576120(TCF7)
PSS: 102446665(TCF7)
CMY: 102943166
CPIC: 101937399(TCF7)
ACS: 100554608(tcf7)
PVT: 110079405(TCF7)
PBI: 103067042(TCF7)
PMUR: 107294908(TCF7)
GJA: 107125983(TCF7)
XLA: 398658(tcf7.S)
XTR: 395061(tcf7)
NPR: 108792126(TCF7)
DRE: 497649(tcf7)
SANH: 107661683(tcf7) 107692971
SGH: 107603263
IPU: 108278866(tcf7)
PHYP: 113535749
AMEX: 103045826
EEE: 113578029(tcf7)
TRU: 101076516(tcf7)
NCC: 104960861(tcf7)
XMA: 111610761
XCO: 114157642
PRET: 103460015(tcf7) 103480959
NFU: 107386837(tcf7)
KMR: 108238102(tcf7)
AOCE: 111566135
CSEM: 103394864(tcf7)
POV: 109635808(tcf7)
SDU: 111234495(tcf7)
BPEC: 110153986(tcf7)
PKI: 111839551
LCM: 102350321(TCF7)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1569101
  Authors
van de Wetering M, Oosterwegel M, Holstege F, Dooyes D, Suijkerbuijk R, Geurts van Kessel A, Clevers H
  Title
The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.
  Journal
J Biol Chem 267:8530-6 (1992)
  Sequence
[hsa:6932]
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056
Reference
  Authors
Ioannidis V, Beermann F, Clevers H, Held W
  Title
The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.
  Journal
Nat Immunol 2:691-7 (2001)
DOI:10.1038/90623
  Sequence
[mmu:21414]
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