KEGG   ORTHOLOGY: K04273
Entry
K04273                      KO                                     

Name
LPAR6, P2RY5
Definition
lysophosphatidic acid receptor 6
Pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko05200  Pathways in cancer
Disease
H00667  Woolly hair
H00784  Localized autosomal recessive hypotrichosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
   04151 PI3K-Akt signaling pathway
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
Other DBs
GO: 0070915
Genes
HSA: 10161(LPAR6)
PTR: 741241(LPAR6)
PPS: 100974511(LPAR6)
GGO: 101132139(LPAR6)
PON: 100432438(LPAR6)
NLE: 100588296(LPAR6)
MCC: 705081(LPAR6)
MCF: 102145478(LPAR6)
CSAB: 103214404(LPAR6)
RRO: 104662759(LPAR6)
RBB: 108530743(LPAR6)
CJC: 100398639(LPAR6)
SBQ: 101038623(LPAR6)
MMU: 67168(Lpar6)
MCAL: 110309180(Lpar6)
MPAH: 110325234(Lpar6)
RNO: 691774(Lpar6)
MUN: 110553593(Lpar6)
CGE: 100750873(Lpar6)
NGI: 103726741(Lpar6)
HGL: 101703338(Lpar6)
CCAN: 109691097(Lpar6)
OCU: 103352130(LPAR6)
TUP: 102494278(LPAR6)
CFA: 100856069(LPAR6)
VVP: 112933949(LPAR6)
AML: 100475559(LPAR6)
UMR: 103677601(LPAR6)
UAH: 113251326(LPAR6)
ORO: 101386667(LPAR6)
ELK: 111146912
FCA: 101095629(LPAR6)
PTG: 102965799(LPAR6)
PPAD: 109265953(LPAR6)
AJU: 106971998(LPAR6)
BTA: 782518(LPAR6)
BOM: 102285753(LPAR6)
BIU: 109566714(LPAR6)
BBUB: 102399806(LPAR6)
CHX: 102183611(LPAR6)
OAS: 101114118(LPAR6)
SSC: 100738399(LPAR6)
CFR: 102516623(LPAR6)
CDK: 105101802(LPAR6)
BACU: 103013481(LPAR6)
LVE: 103071883(LPAR6)
OOR: 101273284(LPAR6)
DLE: 111175320(LPAR6)
PCAD: 102994918(LPAR6)
ECB: 100629781(LPAR6)
EPZ: 103549434(LPAR6)
EAI: 106829683(LPAR6)
MYB: 102251488(LPAR6)
MYD: 102765968(LPAR6)
MNA: 107531401(LPAR6)
HAI: 109387139(LPAR6)
DRO: 112313055(LPAR6)
PALE: 102892775(LPAR6)
RAY: 107520928(LPAR6)
MJV: 108384784(LPAR6)
LAV: 100669291(LPAR6)
TMU: 101356213
MDO: 103102093(LPAR6)
SHR: 105749898(LPAR6)
PCW: 110213449(LPAR6)
OAA: 103170464(LPAR6)
GGA: 396118(LPAR6)
MGP: 100541942(PUSL1) 100548273(LPAR6) 116216169
CJO: 107308153(LPAR6) 107323273
NMEL: 110387731(LPAR6) 110408725
APLA: 101792915(LPAR6) 101794174
ACYG: 106035041(LPAR6) 106044634
TGU: 101233928(LPAR6)
LSR: 110469559(LPAR6)
SCAN: 103827407(LPAR6)
GFR: 102042956(LPAR6)
FAB: 101810970(LPAR6)
PHI: 102104985(LPAR6)
PMAJ: 107203091(LPAR6)
CCAE: 111939055(LPAR6)
CCW: 104689971(LPAR6) 104693316
ETL: 114060930(LPAR6) 114071275
FPG: 101912931(LPAR6) 101922080
FCH: 102049640 102051394(LPAR6)
CLV: 102086710(LPAR6) 102097365(PUSL1)
EGZ: 104131601(LPAR6) 104133372
NNI: 104009057 104010902(LPAR6)
ACUN: 113486889(LPAR6) 113487787
PADL: 103913464(LPAR6) 103917946
AAM: 106489230(LPAR6) 106495565
CMY: 102932175 102933729(LPAR6)
ACS: 100553477 103279739(lpar6)
PVT: 110073288
PMUR: 107284300(LPAR6) 107287530
TSR: 106543704(LPAR6) 106547704
PMUA: 114582719(LPAR6) 114595052 114602514(PUSL1)
XLA: 100036865(LOC100497020.L) 101243551(lpar6.L) 108703519 108709805(lpar6.S) 108711753
DRE: 101884764(lpar6b) 110437788 571773(lpar6a)
RTP: 109922608 109937909(lpar6)
SOC: 105203641
AEC: 105143286
ACEP: 105625488
LHU: 105678724
OBO: 105278269
EPA: 110243809
PDAM: 113683977
HMG: 101236394
 » show all
Reference
  Authors
Pasternack SM, von Kugelgen I, Aboud KA, Lee YA, Ruschendorf F, Voss K, Hillmer AM, Molderings GJ, Franz T, Ramirez A, Nurnberg P, Nothen MM, Betz RC
  Title
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.
  Journal
Nat Genet 40:329-34 (2008)
DOI:10.1038/ng.84
  Sequence
[hsa:10161]
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