KEGG   ORTHOLOGY: K04347Help
Entry
K04347                      KO                                     

Name
GNG12
Definition
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04062  Chemokine signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04371  Apelin signaling pathway
ko04713  Circadian entrainment
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04810  Regulation of actin cytoskeleton
ko04926  Relaxin signaling pathway
ko05032  Morphine addiction
ko05034  Alcoholism
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04010 MAPK signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04371 Apelin signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04151 PI3K-Akt signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  09156 Nervous system
   04724 Glutamatergic synapse
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04727 GABAergic synapse
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04725 Cholinergic synapse
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04728 Dopaminergic synapse
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04726 Serotonergic synapse
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04723 Retrograde endocannabinoid signaling
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  09165 Substance dependence
   05032 Morphine addiction
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   05034 Alcoholism
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   05163 Human cytomegalovirus infection
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
   04031 GTP-binding proteins
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  Exosomal proteins of colorectal cancer cells
   K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
BRITE hierarchy
Genes
HSA: 55970(GNG12)
PTR: 100609242(GNG12)
GGO: 101147632(GNG12)
PON: 100173039(GNG12)
NLE: 100584569(GNG12)
MCC: 100424606(GNG12)
MCF: 102126944(GNG12)
CSAB: 103224649(GNG12)
RRO: 104657305(GNG12)
RBB: 108532869(GNG12)
CJC: 100394978(GNG12) 100396640
SBQ: 101046368(GNG12) 101051683
MMU: 100503710(Gm5741) 14701(Gng12)
MCAL: 110296551(Gng12) 110300627(Gng14)
MPAH: 110314464(Gng12) 110337711(Gng14)
RNO: 114120(Gng12) 685513
MUN: 110545821(Gng14) 110558424(Gng12)
CGE: 100757536(Gng12) 107978884(Gng14)
NGI: 103743355(Gng12) 103751889
HGL: 101725110(Gng12)
CCAN: 109681247 109698314(Gng12)
OCU: 103350153(GNG12) 108176185
TUP: 102501535(GNG12)
CFA: 100686332(GNG12) 611002(GNG14)
VVP: 112908054(GNG14) 112910524(GNG12)
AML: 100477221 100477225(GNG12)
UMR: 103663028(GNG12)
UAH: 113247141(GNG14) 113254546(GNG12)
FCA: 101084346(GNG14) 101089378(GNG12)
PTG: 102951416(GNG12)
AJU: 106985197(GNG12) 113596552(GNG14)
BTA: 286850(GNG12) 529425
BOM: 102271265 102287427(GNG12)
BIU: 109556175(GNG12) 109561546
BBUB: 102396193(GNG14) 102402691(GNG12)
PHD: 102335353 102341852(GNG12)
CHX: 102175543(GNG12) 102182581
OAS: 101115838(GNG12) 106991180(GNG14)
SSC: 100270820(GNG12) 100520008(GNG14)
CFR: 106729205
CDK: 105104066
DLE: 111166783(GNG14) 111178437(GNG12)
PCAD: 102976485(GNG14) 112063854(GNG12)
ECB: 100063518(GNG14) 100630574(GNG12)
EPZ: 103542772 103564847(GNG12)
EAI: 106825068(GNG12) 106826929
MYB: 102240295 102242875(GNG12)
MYD: 102752682(GNG12) 102773554
MNA: 107533406(GNG12) 107541527
HAI: 109394259
RSS: 109447689(GNG12) 109454960
DRO: 112301587(GNG14) 112309207(GNG12)
PALE: 102877921(GNG14) 102886682(GNG12)
RAY: 107519408 107520565(GNG12)
LAV: 111750996(GNG12) 111751488(GNG14)
MDO: 100010184 100016914(GNG12)
SHR: 100914479(GNG12) 100920266(GNG14)
PCW: 110212886(GNG12) 110214163(GNG14)
OAA: 100078907(GNG14) 100081920(GNG12)
GGA: 772239(GNG12)
MGP: 100539211(GNG12)
CJO: 107317807(GNG12)
NMEL: 110402591(GNG12)
APLA: 101790756(GNG12)
ACYG: 106043621(GNG12)
TGU: 100190560(GNG12)
LSR: 110473246(GNG12)
SCAN: 103815078(GNG12)
GFR: 102042757(GNG12)
FAB: 101807832(GNG12)
PHI: 102102678(GNG12)
PMAJ: 107208454(GNG12)
CCAE: 111932951(GNG12)
CCW: 104695124(GNG12)
ETL: 114061073(GNG12)
FPG: 101918590(GNG12)
FCH: 102049350(GNG12)
CLV: 102084634(GNG12)
EGZ: 104123920(GNG12)
NNI: 104009239(GNG12)
ACUN: 113482585(GNG12)
PADL: 103913977(GNG12)
AAM: 106486519(GNG12)
ASN: 102371926(GNG12)
AMJ: 102574789(GNG12)
PSS: 102449936(GNG12)
CMY: 102930776 102947603(GNG12)
CPIC: 101933719(GNG12) 101941988
ACS: 100554637(gng12)
PVT: 110079856(GNG12)
PBI: 103059345(GNG12)
PMUR: 107299301(GNG12)
GJA: 107114357(GNG12) 107114377
XLA: 108715518 595043(gng12.L)
XTR: 100124710(gng12)
NPR: 108795949(GNG12)
DRE: 100331581(si:dkey-44g17.6) 406604(gng12a)
TRU: 101074215
NCC: 104956611
PRET: 103463990 103479128(gng12)
CSEM: 103392942 103396088(gng12)
HCQ: 109524140
LCM: 102348748(GNG12)
CMK: 103189133(gng12)
DPX: DAPPUDRAFT_44980(Gng2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cook LA, Schey KL, Cleator JH, Wilcox MD, Dingus J, Hildebrandt JD
  Title
Identification of a region in G protein gamma subunits conserved across species but hypervariable among subunit isoforms.
  Journal
Protein Sci 10:2548-55 (2001)
DOI:10.1110/ps.ps.26401
  Sequence
[hsa:55970]
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