KEGG   ORTHOLOGY: K04350Help
Entry
K04350                      KO                                     

Name
RASGRP1
Definition
RAS guanyl-releasing protein 1
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04611  Platelet activation
ko04660  T cell receptor signaling pathway
ko05200  Pathways in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K04350  RASGRP1; RAS guanyl-releasing protein 1
   04010 MAPK signaling pathway
    K04350  RASGRP1; RAS guanyl-releasing protein 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04350  RASGRP1; RAS guanyl-releasing protein 1
   04660 T cell receptor signaling pathway
    K04350  RASGRP1; RAS guanyl-releasing protein 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04350  RASGRP1; RAS guanyl-releasing protein 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04350  RASGRP1; RAS guanyl-releasing protein 1
BRITE hierarchy
Other DBs
GO: 0005088
Genes
HSA: 10125(RASGRP1)
PTR: 453316(RASGRP1)
PPS: 100983198(RASGRP1)
GGO: 101132761(RASGRP1)
PON: 100451529(RASGRP1)
NLE: 100584529(RASGRP1)
MCC: 703838(RASGRP1)
MCF: 102124752(RASGRP1)
CSAB: 103245866(RASGRP1)
RRO: 104659684(RASGRP1)
RBB: 108526992(RASGRP1)
CJC: 100390905(RASGRP1)
SBQ: 101030982(RASGRP1)
MMU: 19419(Rasgrp1)
MCAL: 110311236(Rasgrp1)
MPAH: 110317644(Rasgrp1)
RNO: 29434(Rasgrp1)
MUN: 110565085(Rasgrp1)
CGE: 100762037(Rasgrp1)
NGI: 103727451(Rasgrp1)
HGL: 101699646(Rasgrp1)
CCAN: 109699067(Rasgrp1)
OCU: 100359319(RASGRP1)
TUP: 102468376(RASGRP1)
CFA: 478255(RASGRP1)
VVP: 112919851(RASGRP1)
AML: 100483012(RASGRP1)
UMR: 103673478(RASGRP1)
UAH: 113242056(RASGRP1)
ORO: 101372513(RASGRP1)
ELK: 111140724
FCA: 101093110(RASGRP1)
PTG: 102957207(RASGRP1)
PPAD: 109263183(RASGRP1)
AJU: 106985820(RASGRP1)
BTA: 533125(RASGRP1)
BOM: 102272711(RASGRP1)
BIU: 109564913(RASGRP1)
BBUB: 102412333(RASGRP1)
CHX: 102173007(RASGRP1)
OAS: 101105504(RASGRP1)
SSC: 100522721(RASGRP1)
CFR: 102511050(RASGRP1)
CDK: 105096898(RASGRP1)
BACU: 103019762(RASGRP1)
LVE: 103080961(RASGRP1)
OOR: 101284173(RASGRP1)
DLE: 111181766(RASGRP1)
PCAD: 102981768(RASGRP1)
ECB: 100071578(RASGRP1)
EPZ: 103560184(RASGRP1)
EAI: 106835159(RASGRP1)
MYB: 102262016(RASGRP1)
MYD: 102758449(RASGRP1)
MNA: 107542952(RASGRP1)
HAI: 109393855(RASGRP1)
DRO: 112311978(RASGRP1)
PALE: 102877927(RASGRP1)
RAY: 107514450(RASGRP1)
MJV: 108397030(RASGRP1)
LAV: 100667149(RASGRP1)
TMU: 101343790
MDO: 100031728(RASGRP1)
SHR: 100923297(RASGRP1)
PCW: 110211064(RASGRP1)
OAA: 100089033(RASGRP1)
GGA: 423290(RASGRP1)
MGP: 100544082(RASGRP1)
CJO: 107314952(RASGRP1)
NMEL: 110401152(RASGRP1)
APLA: 101794229(RASGRP1)
ACYG: 106031708(RASGRP1)
TGU: 100224858(RASGRP1)
LSR: 110475275(RASGRP1)
SCAN: 103826949(RASGRP1)
GFR: 102045446(RASGRP1)
FAB: 101821862(RASGRP1)
PHI: 102102932(RASGRP1)
PMAJ: 107205693(RASGRP1)
CCAE: 111930328(RASGRP1)
CCW: 104684250(RASGRP1)
ETL: 114055314(RASGRP1)
FPG: 101916013(RASGRP1)
FCH: 102054590(RASGRP1)
CLV: 102091121(RASGRP1)
EGZ: 104122054(RASGRP1)
NNI: 104015904(RASGRP1)
ACUN: 113480591(RASGRP1)
PADL: 103914379(RASGRP1)
AAM: 106483025(RASGRP1)
ASN: 102379336(RASGRP1)
AMJ: 106736825(RASGRP1)
PSS: 102448788(RASGRP4) 102460370(RASGRP1) 112547394
CMY: 102941071(RASGRP1)
CPIC: 101946271(RASGRP1)
ACS: 100563703(rasgrp1)
PVT: 110085751(RASGRP1)
PBI: 103050553(RASGRP1)
PMUR: 107287220(RASGRP1)
TSR: 106550700(RASGRP1)
PMUA: 114593501(RASGRP1)
GJA: 107118948(RASGRP1)
XLA: 108698641(rasgrp4.L) 108699715(rasgrp1.S) 414479(rasgrp1.L)
XTR: 100101791(rasgrp1) 100496432(rasgrp4)
NPR: 108785170(RASGRP1)
DRE: 558453(rasgrp4)
SGH: 107560135(rasgrp1) 107596887
LCO: 104921335(rasgrp1) 104934274
NCC: 104955748 104963649(rasgrp1)
MZE: 101472166 101480824(rasgrp1)
ONL: 100699303(rasgrp1) 100709303
OLA: 101159840 101169327(rasgrp1)
XMA: 102217156(rasgrp1) 102218567
XCO: 114133467 114134217(rasgrp1)
PRET: 103458502(rasgrp1) 103475112
CVG: 107091620 107097081(rasgrp1)
NFU: 107379830 107392423(rasgrp1)
KMR: 108237197(rasgrp1) 108244670
ALIM: 106520349(rasgrp1) 106529664 106536568
AOCE: 111579599 111583646(rasgrp1)
CSEM: 103377852 103399991(rasgrp1)
POV: 109627793(rasgrp1) 109630234
SDU: 111216984 111225600(rasgrp1)
SLAL: 111662274 111663201(rasgrp1)
HCQ: 109510720 109526140(rasgrp1)
BPEC: 110155573(rasgrp1) 110163618
MALB: 109963281 109967968(rasgrp1)
LCM: 102345538(RASGRP4) 102347423(RASGRP1)
CMK: 103175195(rasgrp1) 103190331(rasgrp4)
CIN: 100175460
ADF: 107332510
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Stone JC
  Title
Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells.
  Journal
Genes Cancer 2:320-34 (2011)
DOI:10.1177/1947601911408082
Reference
PMID:9789079
  Authors
Kawasaki H, Springett GM, Toki S, Canales JJ, Harlan P, Blumenstiel JP, Chen EJ, Bany IA, Mochizuki N, Ashbacher A, Matsuda M, Housman DE, Graybiel AM
  Title
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.
  Journal
Proc Natl Acad Sci U S A 95:13278-83 (1998)
DOI:10.1073/pnas.95.22.13278
  Sequence
[hsa:10125]
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