KEGG   ORTHOLOGY: K04353
Entry
K04353                      KO                                     

Name
RAP1A
Definition
Ras-related protein Rap-1A
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04720  Long-term potentiation
ko04722  Neurotrophin signaling pathway
ko04934  Cushing syndrome
ko04972  Pancreatic secretion
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04014 Ras signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04015 Rap1 signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04024 cAMP signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04353  RAP1A; Ras-related protein Rap-1A
   04530 Tight junction
    K04353  RAP1A; Ras-related protein Rap-1A
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04353  RAP1A; Ras-related protein Rap-1A
   04670 Leukocyte transendothelial migration
    K04353  RAP1A; Ras-related protein Rap-1A
   04062 Chemokine signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
  09154 Digestive system
   04972 Pancreatic secretion
    K04353  RAP1A; Ras-related protein Rap-1A
  09156 Nervous system
   04720 Long-term potentiation
    K04353  RAP1A; Ras-related protein Rap-1A
   04722 Neurotrophin signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K04353  RAP1A; Ras-related protein Rap-1A
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04353  RAP1A; Ras-related protein Rap-1A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K04353  RAP1A; Ras-related protein Rap-1A
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    K04353  RAP1A; Ras-related protein Rap-1A
Genes
HSA: 5906(RAP1A)
PTR: 469408(RAP1A)
PPS: 100980934(RAP1A)
GGO: 101125618(RAP1A)
PON: 100433839(RAP1A)
NLE: 100603891(RAP1A)
MCC: 704404(RAP1A)
MCF: 102144586(RAP1A)
CSAB: 103224221(RAP1A)
RRO: 104658932(RAP1A)
RBB: 108525739 108528085(RAP1A)
CJC: 100393183(RAP1A)
SBQ: 101048450(RAP1A)
MMU: 109905(Rap1a)
MCAL: 110290796(Rap1a)
MPAH: 110319932(Rap1a)
RNO: 295347(Rap1a)
MUN: 110549551(Rap1a)
CGE: 100751497(Rap1a)
NGI: 103734905(Rap1a)
HGL: 101698757(Rap1a)
CCAN: 109695156(Rap1a)
OCU: 100351588(RAP1A)
TUP: 102475072(RAP1A)
CFA: 483225(RAP1A)
VVP: 112907935(RAP1A)
AML: 100471801(RAP1A)
UMR: 103675043(RAP1A)
UAH: 113244427(RAP1A)
ORO: 101375466(RAP1A)
ELK: 111143648
FCA: 101094942(RAP1A)
PTG: 102963243(RAP1A)
PPAD: 109272045(RAP1A)
AJU: 106969628(RAP1A)
BTA: 282031(RAP1A)
BOM: 102286224(RAP1A)
BIU: 109555931(RAP1A)
BBUB: 102394947(RAP1A)
CHX: 102176930(RAP1A)
OAS: 101115080(RAP1A)
SSC: 100153199(RAP1A)
CFR: 102516450(RAP1A)
CDK: 105102039(RAP1A)
BACU: 103017880(RAP1A)
LVE: 103069239(RAP1A)
OOR: 101287340(RAP1A)
DLE: 111180034(RAP1A)
PCAD: 102985661(RAP1A)
ECB: 100049912 100058930(RAP1A)
EPZ: 103547802(RAP1A)
EAI: 106828599(RAP1A)
MYB: 102258771(RAP1A)
MYD: 102774675(RAP1A)
MNA: 107545324(RAP1A)
HAI: 109373546(RAP1A)
DRO: 112313714(RAP1A)
PALE: 102879271(RAP1A)
RAY: 107499843(RAP1A)
MJV: 108395546(RAP1A)
LAV: 100676220(RAP1A)
TMU: 101352801
MDO: 100033128(RAP1A)
SHR: 100935403(RAP1A)
PCW: 110218764(RAP1A)
OAA: 100076731(RAP1A)
GGA: 419867(RAP1A)
MGP: 100151696(RAP1A)
CJO: 107324916(RAP1A)
NMEL: 110388047(RAP1A)
APLA: 101800296(RAP1A)
ACYG: 106041314(RAP1A)
TGU: 100151697(RAP1A)
LSR: 110475399(RAP1A)
SCAN: 103823268(RAP1A)
GFR: 102036447(RAP1A)
FAB: 101806584(RAP1A)
PHI: 102112636(RAP1A)
PMAJ: 107214847(RAP1A)
CCAE: 111939824(RAP1A)
CCW: 104692321(RAP1A)
ETL: 114063112(RAP1A)
FPG: 101924077(RAP1A)
FCH: 102052801(RAP1A)
CLV: 102089030(RAP1A)
EGZ: 104126794(RAP1A)
NNI: 104010315(RAP1A)
ACUN: 113488776(RAP1A)
PADL: 103923560(RAP1A)
AAM: 106485263(RAP1A)
ASN: 102385556(RAP1A)
AMJ: 102571106(RAP1A)
PSS: 102461781(RAP1A)
CMY: 102948045(RAP1A)
CPIC: 101952443(RAP1A)
ACS: 100556443(rap1a)
PVT: 110072354(RAP1A)
PBI: 103065471(RAP1A)
PMUR: 107292543(RAP1A)
TSR: 106550518
PMUA: 114599364(RAP1A)
GJA: 107112269(RAP1A)
XLA: 414290(rap1a) 779127(rap1a.L) 780738
XTR: 100124947(rap1a)
NPR: 108789680(RAP1A)
DRE: 406714(rap1ab) 415242(rap1aa)
IPU: 108255244(rap1b) 108265690(rap1a)
PHYP: 113526347(rap1a) 113538035
AMEX: 103022868 103047011(rap1a)
EEE: 113572077(rap1a) 113586523
NCC: 104961557
CSEM: 103385603 103386699(rap1a)
SASA: 106566052(RAP1A) 106567206(RAP1B) 106572472(RAP1B) 106582744(RAP1B)
ELS: 105022336(rap1b) 105023688(rap1a)
SFM: 108928254(rap1a) 108930477
PKI: 111839862 111851087(rap1a)
LCM: 102354992(RAP1A)
CMK: 103182425(rap1a)
RTP: 109939006(rap1b)
CIN: 445785(rap1b)
APLC: 110982135
DME: Dmel_CG1956(Rap1)
DER: 6546030
DSE: 6610415
DSI: Dsimw501_GD13432(Dsim_R)
DAN: 6507581
DSR: 110177618
DPE: 6595862
DMN: 108152172
DWI: 6645841
DAZ: 108612588
DNV: 115564307
DHE: 111596946
DVI: 6622391
MDE: 101892158
AAG: 5571900
AME: 413246
BIM: 100747441
BTER: 100642405
CCAL: 108628416
OBB: 114877648
SOC: 105197651
MPHA: 105834702
AEC: 105152361
ACEP: 105626421
PBAR: 105431454
VEM: 105562403
HST: 105187881
DQU: 106748251
CFO: 105257324
LHU: 105667796
PGC: 109860604
OBO: 105286800
PCF: 106786548
NVI: 100117170
CSOL: 105362693
MDL: 103568558
TCA: 658243
DPA: 109533808
ATD: 109602368
NVL: 108560620
BMOR: 692519(Ras3)
BMAN: 114253491
PMAC: 106712843
PRAP: 111000490
HAW: 110375343
TNL: 113497012
PXY: 105387719
API: 100166893
DNX: 107165088
AGS: 114120531
RMD: 113556321
BTAB: 109038859
CLEC: 106666901
ZNE: 110835691
TUT: 107362689
DPTE: 113795806
PTEP: 107449408
CEL: CELE_C27B7.8(rap-1)
BMY: Bm1_39445
PCAN: 112572369
OBI: 106872353
SHX: MS3_03938
PDAM: 113665889
SPIS: 111340737
DGT: 114521782
TASA: A1Q1_04105
DDI: DDB_G0272857(rapB)
DPP: DICPUDRAFT_26434(rapB)
DFA: DFA_02753
EHI: EHI_004860(203.t00010) EHI_049030 EHI_058090(179.t00009) EHI_101260(5.t00090)
 » show all
Reference
PMID:2642744
  Authors
Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M
  Title
A ras-related gene with transformation suppressor activity.
  Journal
Cell 56:77-84 (1989)
DOI:10.1016/0092-8674(89)90985-9
  Sequence
[hsa:5906]
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