KEGG   ORTHOLOGY: K04362Help
Entry
K04362                      KO                                     

Name
FGFR1, CD331
Definition
fibroblast growth factor receptor 1 [EC:2.7.10.1]
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04520  Adherens junction
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04714  Thermogenesis
ko04810  Regulation of actin cytoskeleton
ko04928  Parathyroid hormone synthesis, secretion and action
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05215  Prostate cancer
ko05218  Melanoma
ko05224  Breast cancer
ko05230  Central carbon metabolism in cancer
Disease
H00031  Breast cancer
H00255  Hypogonadotropic hypogonadism
H00443  Osteoglophonic dysplasia
H00458  Syndromic craniosynostoses
H01207  Trigonocephaly
H01756  Pfeiffer syndrome
H01850  Hartsfield syndrome
H01988  Jackson-Weiss syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04015 Rap1 signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04010 MAPK signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04151 PI3K-Akt signaling pathway
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   04550 Signaling pathways regulating pluripotency of stem cells
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05205 Proteoglycans in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05230 Central carbon metabolism in cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09162 Cancer: specific types
   05218 Melanoma
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05215 Prostate cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   05224 Breast cancer
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
   00536 Glycosaminoglycan binding proteins
    K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K04362  FGFR1, CD331; fibroblast growth factor receptor 1
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
CD molecules [BR:ko04090]
 Proteins
  K04362  CD331, FGFR1; fibroblast growth factor receptor 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Growth factors/receptors
   K04362  FGFR1, CD331; fibroblast growth factor receptor 1
BRITE hierarchy
Other DBs
GO: 0005007
Genes
HSA: 2260(FGFR1)
PTR: 464122(FGFR1)
PPS: 100988115(FGFR1)
GGO: 101152179(FGFR1)
PON: 100174545(FGFR1)
NLE: 100602423(FGFR1)
MCC: 700126(FGFR1)
MCF: 102144714(FGFR1)
CSAB: 103215648(FGFR1)
RRO: 104679640(FGFR1)
RBB: 108512401(FGFR1)
CJC: 100390192(FGFR1)
SBQ: 101033213(FGFR1)
MMU: 14182(Fgfr1)
MCAL: 110299550(Fgfr1)
MPAH: 110336809(Fgfr1)
RNO: 79114(Fgfr1)
MUN: 110563307(Fgfr1)
CGE: 100773586(Fgfr1)
NGI: 103745770(Fgfr1)
HGL: 101700324(Fgfr1)
CCAN: 109688936(Fgfr1)
OCU: 100351861(FGFR1)
TUP: 102484087(FGFR1)
CFA: 100856477(FGFR1)
VVP: 112916136(FGFR1)
AML: 100472630(FGFR1)
UMR: 103659146(FGFR1)
UAH: 113262086(FGFR1)
ORO: 101364849(FGFR1)
FCA: 101086055(FGFR1)
PTG: 102972346(FGFR1)
PPAD: 109262303(FGFR1)
AJU: 106978376(FGFR1)
BTA: 281768(FGFR1)
BOM: 102267776(FGFR1)
BIU: 109553304(FGFR1)
BBUB: 102407288(FGFR1)
CHX: 102180282(FGFR1)
OAS: 780507(FGFR1)
SSC: 100153248(FGFR1)
CFR: 102515264(FGFR1)
CDK: 105105270(FGFR1)
BACU: 103017733(FGFR1)
LVE: 103069902(FGFR1)
OOR: 101279623(FGFR1)
DLE: 111173523(FGFR1)
PCAD: 102989551(FGFR1)
ECB: 100057614(FGFR1)
EPZ: 103560266(FGFR1)
EAI: 106824659(FGFR1)
MYB: 102253832(FGFR1)
MYD: 102759202(FGFR1)
MNA: 107535065(FGFR1)
HAI: 109373149(FGFR1)
DRO: 112306733(FGFR1)
PALE: 102898943(FGFR1)
RAY: 107515961(FGFR1)
MJV: 108403050(FGFR1)
LAV: 100662289(FGFR1)
TMU: 101342270
MDO: 100029852(FGFR1)
SHR: 100914347(FGFR1)
PCW: 110207578(FGFR1)
OAA: 100074240(FGFR1)
GGA: 396516(FGFR1)
MGP: 100547498(FGFR1)
CJO: 107323773(FGFR1)
NMEL: 110387131(FGFR1)
ACYG: 106044374(FGFR1)
TGU: 100221243(FGFR1)
LSR: 110473397(FGFR1)
SCAN: 103822693(FGFR1)
GFR: 102033908(FGFR1) 102037850
FAB: 101822220(FGFR1)
PHI: 102103637(FGFR1)
PMAJ: 107213845(FGFR1)
CCAE: 111922087 111938850(FGFR1)
CCW: 104694904(FGFR1)
ETL: 114066493(FGFR1)
FPG: 101914093(FGFR1)
FCH: 102055369(FGFR1)
CLV: 102085235(FGFR1)
EGZ: 104135322(FGFR1)
NNI: 104016019(FGFR1)
PADL: 103912362(FGFR1)
AAM: 106492992(FGFR1)
ASN: 102386174(FGFR1)
AMJ: 102574117(FGFR1)
PSS: 102461506(FGFR1)
CPIC: 101941076(FGFR1)
ACS: 100559018(fgfr1)
PVT: 110072166(FGFR1)
PBI: 103066603(FGFR1)
PMUR: 107289991(FGFR1)
TSR: 106545617(FGFR1) 106553189
PMUA: 114585343(FGFR1)
GJA: 107113006(FGFR1)
XLA: 394418(fgfr1.L) 397782(xfgfra2) 399444(fgfr1.S)
XTR: 548648(fgfr1)
NPR: 108791453(FGFR1)
DRE: 30705(fgfr1a)
AMEX: 103036914
TRU: 101073964 101078564(fgfr1)
LCO: 104936599(fgfr1) 104938329
OLA: 100125448(fgfr1) 101155126
CVG: 107081801
KMR: 108231094 108247308(fgfr1)
LCM: 102361014(FGFR1)
RTP: 109926304
CIN: 445706(fgfr)
SPU: 373310(FGFR)
NVI: 100114847
TSP: Tsp_00617
MYI: 110455439
OBI: 106883548
EGL: EGR_04208
AQU: 100632318
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1697263
  Authors
Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J
  Title
Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.
  Journal
EMBO J 9:2685-92 (1990)
  Sequence
[hsa:2260]
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