KEGG   ORTHOLOGY: K04379Help
Entry
K04379                      KO                                     

Name
FOS
Definition
proto-oncogene protein c-fos
Pathway
ko01522  Endocrine resistance
ko04010  MAPK signaling pathway
ko04024  cAMP signaling pathway
ko04210  Apoptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04657  IL-17 signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04668  TNF signaling pathway
ko04713  Circadian entrainment
ko04725  Cholinergic synapse
ko04728  Dopaminergic synapse
ko04915  Estrogen signaling pathway
ko04917  Prolactin signaling pathway
ko04921  Oxytocin signaling pathway
ko04926  Relaxin signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko04935  Growth hormone synthesis, secretion and action
ko05031  Amphetamine addiction
ko05130  Pathogenic Escherichia coli infection
ko05132  Salmonella infection
ko05133  Pertussis
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05161  Hepatitis B
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05224  Breast cancer
ko05231  Choline metabolism in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05323  Rheumatoid arthritis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04668 TNF signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04024 cAMP signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04379  FOS; proto-oncogene protein c-fos
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04660 T cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04658 Th1 and Th2 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04659 Th17 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04657 IL-17 signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04662 B cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04917 Prolactin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04921 Oxytocin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04926 Relaxin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04935 Growth hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
   04928 Parathyroid hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
  09156 Nervous system
   04725 Cholinergic synapse
    K04379  FOS; proto-oncogene protein c-fos
   04728 Dopaminergic synapse
    K04379  FOS; proto-oncogene protein c-fos
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04379  FOS; proto-oncogene protein c-fos
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04379  FOS; proto-oncogene protein c-fos
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05231 Choline metabolism in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04379  FOS; proto-oncogene protein c-fos
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04379  FOS; proto-oncogene protein c-fos
   05224 Breast cancer
    K04379  FOS; proto-oncogene protein c-fos
  09163 Immune disease
   05323 Rheumatoid arthritis
    K04379  FOS; proto-oncogene protein c-fos
  09165 Substance dependence
   05031 Amphetamine addiction
    K04379  FOS; proto-oncogene protein c-fos
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04379  FOS; proto-oncogene protein c-fos
   05132 Salmonella infection
    K04379  FOS; proto-oncogene protein c-fos
   05135 Yersinia infection
    K04379  FOS; proto-oncogene protein c-fos
   05133 Pertussis
    K04379  FOS; proto-oncogene protein c-fos
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05170 Human immunodeficiency virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05162 Measles
    K04379  FOS; proto-oncogene protein c-fos
   05161 Hepatitis B
    K04379  FOS; proto-oncogene protein c-fos
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04379  FOS; proto-oncogene protein c-fos
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K04379  FOS; proto-oncogene protein c-fos
   05142 Chagas disease (American trypanosomiasis)
    K04379  FOS; proto-oncogene protein c-fos
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04379  FOS; proto-oncogene protein c-fos
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04379  FOS; proto-oncogene protein c-fos
   04131 Membrane trafficking
    K04379  FOS; proto-oncogene protein c-fos
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    K04379  FOS; proto-oncogene protein c-fos
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    K04379  FOS; proto-oncogene protein c-fos
BRITE hierarchy
Genes
HSA: 2353(FOS)
PTR: 453047(FOS)
PPS: 100987957(FOS)
GGO: 101127590(FOS)
PON: 100462290(FOS)
NLE: 100585899(FOS)
MCC: 702077(FOS)
MCF: 102143716(FOS)
CSAB: 103229352(FOS)
RRO: 104677590(FOS)
RBB: 108534930(FOS)
CJC: 100390054(FOS)
SBQ: 101046701(FOS)
MMU: 14281(Fos)
MCAL: 110307063(Fos)
MPAH: 110324365(Fos)
RNO: 314322(Fos)
MUN: 110546962(Fos)
CGE: 100689418(Fos)
NGI: 103747342(Fos)
HGL: 101718383(Fos)
CCAN: 109694000(Fos)
OCU: 100338345(FOS)
TUP: 102491199(FOS)
CFA: 490792(FOS)
VVP: 112927292(FOS)
AML: 100474867(FOS)
UMR: 103671011(FOS)
UAH: 113270317(FOS)
ORO: 101366773(FOS)
ELK: 111148602
FCA: 493935(FOS)
PTG: 102952769(FOS)
PPAD: 109253856(FOS)
AJU: 106974355(FOS)
BTA: 280795(FOS)
BOM: 102275053(FOS)
BIU: 109565363(FOS)
BBUB: 102393791(FOS)
CHX: 102171520(FOS)
OAS: 443218(FOS)
SSC: 100144486(FOS)
CFR: 102519397(FOS)
CDK: 105086086(FOS)
BACU: 102997242(FOS)
LVE: 103084433(FOS)
OOR: 101286650(FOS)
DLE: 111176238(FOS)
PCAD: 102982453(FOS)
ECB: 100051632(FOS)
EPZ: 103548618(FOS)
EAI: 106827712(FOS)
MYB: 102246307(FOS)
MYD: 102764239(FOS)
MNA: 107533821(FOS)
HAI: 109381526(FOS)
DRO: 112311412(FOS)
PALE: 102891428(FOS)
RAY: 107498912(FOS)
MJV: 108402534(FOS)
LAV: 100674799(FOS)
TMU: 101357016
MDO: 100018285(FOS)
SHR: 100924435(FOS)
PCW: 110208312(FOS)
OAA: 100075021(FOS)
GGA: 396512(FOS)
MGP: 104916287
CJO: 107315165(FOS)
NMEL: 110400992(FOS)
APLA: 101801698(FOS)
ACYG: 106038794(FOS)
TGU: 100222961(FOS)
LSR: 110477175(FOS)
SCAN: 103826521(FOS)
GFR: 102037526(FOS)
FAB: 101807505(FOS)
PHI: 102103181(FOS)
PMAJ: 107206453(FOS)
CCAE: 111945660(FOS)
CCW: 104685225(FOS)
ETL: 114056015(FOS)
FPG: 101921708(FOS)
CLV: 102098648(FOS)
NNI: 104020992(FOS)
ACUN: 113480870(FOS)
PADL: 103912965(FOS)
AAM: 106483057(FOS)
ASN: 102385076(FOS)
AMJ: 102562416(FOS)
PSS: 102454531(FOS)
CMY: 102940899(FOS)
CPIC: 101937366(FOS)
ACS: 100556427(fos)
PVT: 110079111(FOS)
PBI: 103049145(FOS)
PMUR: 107285955(FOS)
TSR: 106545095(FOS)
PMUA: 114591829(FOS)
GJA: 107118325(FOS)
XLA: 108698676(fos.L) 447201(fos.S)
XTR: 548954(fos)
NPR: 108802481(FOS)
DRE: 394198(fosab) 564403(si:ch211-153j24.3) 570238(fosaa)
LCM: 102361375(FOS)
CMK: 103189966(fos)
CIN: 778607(fos)
VG: 1491891(gag-FOS)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Vesely PW, Staber PB, Hoefler G, Kenner L
  Title
Translational regulation mechanisms of AP-1 proteins.
  Journal
Mutat Res 682:7-12 (2009)
DOI:10.1016/j.mrrev.2009.01.001
Reference
PMID:6574479
  Authors
van Straaten F, Muller R, Curran T, Van Beveren C, Verma IM
  Title
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
  Journal
Proc Natl Acad Sci U S A 80:3183-7 (1983)
DOI:10.1073/pnas.80.11.3183
  Sequence
[hsa:2353]
Reference
  Authors
Portal MM, Ferrero GO, Caputto BL
  Title
N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.
  Journal
Oncogene 26:3551-8 (2007)
DOI:10.1038/sj.onc.1210137
  Sequence
[hsa:2353]
LinkDB All DBs

DBGET integrated database retrieval system