KEGG ORTHOLOGY: K04390

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04668 TNF signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04217 Necroptosis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04115 p53 signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05205 Proteoglycans in cancer
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05330 Allograft rejection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05332 Graft-versus-host disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05022 Pathways of neurodegeneration - multiple diseases
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04932 Non-alcoholic fatty liver disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05161 Hepatitis B
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05160 Hepatitis C
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05164 Influenza A
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05162 Measles
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05168 Herpes simplex virus 1 infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05163 Human cytomegalovirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05169 Epstein-Barr virus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05165 Human papillomavirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05143 African trypanosomiasis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04090 CD molecules
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
Cytokine receptors [BR:ko04050]
Tumor necrosis factor receptors
  TNF receptor superfamily
   K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
CD molecules [BR:ko04090]
Proteins
  K04390  CD95, FAS; tumor necrosis factor receptor superfamily, member 6

Other DBs

GO:

0005031

Genes

HSA:

355(FAS)

PTR:	738331(FAS)

PPS:	100988526(FAS)

GGO:	101152441(FAS)

NLE:	100580318(FAS)

MCC:	574332(FAS)

MCF:	102140989(FAS)

CSAB:

103216224(FAS)

RRO:	104675147(FAS)

RBB:	108526609(FAS)

CJC:	100397803(FAS)

SBQ:	101035635(FAS)

MMU:	14102(Fas)

MCAL:

110285655(Fas)

MPAH:

110332797(Fas)

RNO:	246097(Fas)

MUN:	110561521(Fas)

CGE:	100762537(Fas)

NGI:	103738053(Fas)

HGL:	101704746(Fas)

CCAN:

109691142(Fas)

OCU:	100008609(FAS)

TUP:	102476587(FAS)

CFA:	486469(FAS)

VVP:	112931965(FAS)

AML:	100473767(FAS)

UMR:	103661934(FAS)

UAH:	113258968(FAS)

ORO:	101369551(FAS)

ELK:

111144883

FCA:	493881(FAS)

PTG:	102958442(FAS)

PPAD:

109255367(FAS)

AJU:	106980953(FAS)

BTA:	282488(FAS)

BOM:	102273906(FAS)

BIU:	109579171(FAS)

BBUB:

102408756(FAS)

CHX:	102180451(FAS)

OAS:	100144426(FAS)

SSC:	396826(FAS)

CFR:	102518538(FAS)

CDK:	105102832(FAS)

BACU:

103020508(FAS)

LVE:	103080104(FAS)

OOR:	101284022(FAS)

DLE:	111172519(FAS)

PCAD:

102985097(FAS)

ECB:	100071639(FAS)

EPZ:	103558124(FAS)

EAI:	106822180(FAS)

MYB:	102259838(FAS)

MYD:	102760302(FAS)

MNA:	107543257(FAS)

HAI:	109377126(FAS)

DRO:	112307358(FAS)

PALE:

102879561(FAS)

RAY:	107502212(FAS)

MJV:	108392867(FAS)

LAV:	100657715(FAS)

TMU:

101346704

SHR:	105749219(FAS)

PCW:	110198951(FAS)

OAA:	103165091(FAS)

GGA:	395274(FAS)

MGP:	100550139(FAS)

CJO:	107315904(FAS)

NMEL:

110400542(FAS)

APLA:

101796331(FAS)

ACYG:

106030038(FAS)

TGU:	100225721(FAS)

LSR:	110475612(FAS)

SCAN:

103814184(FAS)

GFR:	102033034(FAS)

FAB:	101806294(FAS)

PHI:	102102426(FAS)

PMAJ:

107206851(FAS)

CCAE:

111930915(FAS)

CCW:	104696515(FAS)

ETL:	114055892(FAS)

FPG:	101911760(FAS)

FCH:	102048640(FAS)

CLV:	102087399(FAS)

EGZ:	104129042(FAS)

NNI:	104013978(FAS)

ACUN:

113481795

PADL:

103913942(FAS)

AAM:	106487830(FAS)

ASN:	102375471(FAS)

AMJ:	102562734(FAS)

PSS:	102463316(FAS)

CMY:	102944566(FAS)

CPIC:

101938109(FAS)

ACS:	100551688(fas)

PVT:	110083121(FAS)

PBI:

103050181

PMUA:

114597296(FAS)

GJA:	107121652(FAS)

XLA:	108696050 108697171

XTR:	100124750(fas)

DRE:	768248(fas)

SRX:	107715957 107744555

SANH:

107670847 107689821

SGH:	107554068 107583548

CCAR:

IPU:

PHYP:

AMEX:

EEE:

TRU:

LCO:

NCC:

MZE:

ONL:

OLA:

XMA:

XCO:

PRET:

CVG:

NFU:

KMR:	108243471(fas)

ALIM:

AOCE:

CSEM:

POV:

LCF:	108897286(fas)

SDU:

SLAL:

HCQ:

BPEC:

MALB:

SASA:

100380364(tnr6) 106577010

OTW:	112253033 112254547

SALP:

111952088 111978817

ELS:

105022722

SFM:	108939520(fas)

PKI:	111853643(fas)

LCM:	102349412(FAS)

CMK:	103180778(fas)

RTP:

109929457

» show all

Reference

PMID:1713127

Authors

Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S

Title

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.

Journal

Cell 66:233-43 (1991)
DOI:10.1016/0092-8674(91)90614-5

Sequence

[hsa:355]

Reference

PMID:24953023

Authors

Riccio M, Carnevale G, Cardinale V, Gibellini L, De Biasi S, Pisciotta A, Carpino G, Gentile R, Berloco PB, Brunelli R, Bastianelli C, Napoletano C, Cantafora A, Cossarizza A, Gaudio E, Alvaro D, De Pol A

Title

The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells.

Journal

J Hepatol 61:1097-105 (2014)
DOI:10.1016/j.jhep.2014.06.016

Sequence

[hsa:355]

LinkDB

DBGET integrated database retrieval system