ORTHOLOGY: K04390
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Entry
K04390 KO
Name
TNFRSF6, FAS, CD95
Definition
tumor necrosis factor receptor superfamily member 6
Pathway
ko01524
Platinum drug resistance
ko04010
MAPK signaling pathway
ko04060
Cytokine-cytokine receptor interaction
ko04115
p53 signaling pathway
ko04210
Apoptosis
ko04217
Necroptosis
ko04650
Natural killer cell mediated cytotoxicity
ko04668
TNF signaling pathway
ko04932
Non-alcoholic fatty liver disease
ko04940
Type I diabetes mellitus
ko05010
Alzheimer disease
ko05022
Pathways of neurodegeneration - multiple diseases
ko05130
Pathogenic Escherichia coli infection
ko05142
Chagas disease
ko05143
African trypanosomiasis
ko05160
Hepatitis C
ko05161
Hepatitis B
ko05162
Measles
ko05163
Human cytomegalovirus infection
ko05164
Influenza A
ko05165
Human papillomavirus infection
ko05167
Kaposi sarcoma-associated herpesvirus infection
ko05168
Herpes simplex virus 1 infection
ko05169
Epstein-Barr virus infection
ko05170
Human immunodeficiency virus 1 infection
ko05200
Pathways in cancer
ko05205
Proteoglycans in cancer
ko05320
Autoimmune thyroid disease
ko05330
Allograft rejection
ko05332
Graft-versus-host disease
Disease
H00005
Chronic lymphocytic leukemia
H00007
Hodgkin lymphoma
H00009
Adult T-cell leukemia
H00017
Esophageal cancer
H00108
Autoimmune lymphoproliferative syndromes
H01463
Mycosis fungoides
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
04668 TNF signaling pathway
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
04217 Necroptosis
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
04115 p53 signaling pathway
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05205 Proteoglycans in cancer
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09163 Immune disease
05320 Autoimmune thyroid disease
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05330 Allograft rejection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05332 Graft-versus-host disease
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09164 Neurodegenerative disease
05010 Alzheimer disease
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05022 Pathways of neurodegeneration - multiple diseases
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
04932 Non-alcoholic fatty liver disease
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05161 Hepatitis B
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05160 Hepatitis C
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05164 Influenza A
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05162 Measles
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05168 Herpes simplex virus 1 infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05163 Human cytomegalovirus infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05167 Kaposi sarcoma-associated herpesvirus infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05169 Epstein-Barr virus infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05165 Human papillomavirus infection
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09174 Infectious disease: parasitic
05142 Chagas disease
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
05143 African trypanosomiasis
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
04090 CD molecules
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
Cytokine receptors [BR:
ko04050
]
Tumor necrosis factor receptors
TNF receptor superfamily
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
CD molecules [BR:
ko04090
]
Proteins
K04390 CD95, FAS; tumor necrosis factor receptor superfamily, member 6
BRITE hierarchy
Other DBs
GO:
0005031
Genes
HSA:
355
(FAS)
PTR:
738331
(FAS)
PPS:
100988526
(FAS)
GGO:
101152441
(FAS)
NLE:
100580318
(FAS)
MCC:
574332
(FAS)
MCF:
102140989
(FAS)
CSAB:
103216224
(FAS)
RRO:
104675147
(FAS)
RBB:
108526609
(FAS)
CJC:
100397803
(FAS)
SBQ:
101035635
(FAS)
MMU:
14102
(Fas)
MCAL:
110285655
(Fas)
MPAH:
110332797
(Fas)
RNO:
246097
(Fas)
MUN:
110561521
(Fas)
CGE:
100762537
(Fas)
NGI:
103738053
(Fas)
HGL:
101704746
(Fas)
CCAN:
109691142
(Fas)
OCU:
100008609
(FAS)
TUP:
102476587
(FAS)
CFA:
486469
(FAS)
VVP:
112931965
(FAS)
AML:
100473767
(FAS)
UMR:
103661934
(FAS)
UAH:
113258968
(FAS)
ORO:
101369551
(FAS)
ELK:
111144883
FCA:
493881
(FAS)
PTG:
102958442
(FAS)
PPAD:
109255367
(FAS)
AJU:
106980953
(FAS)
BTA:
282488
(FAS)
BOM:
102273906
(FAS)
BIU:
109579171
(FAS)
BBUB:
102408756
(FAS)
CHX:
102180451
(FAS)
OAS:
100144426
(FAS)
SSC:
396826
(FAS)
CFR:
102518538
(FAS)
CDK:
105102832
(FAS)
BACU:
103020508
(FAS)
LVE:
103080104
(FAS)
OOR:
101284022
(FAS)
DLE:
111172519
(FAS)
PCAD:
102985097
(FAS)
ECB:
100071639
(FAS)
EPZ:
103558124
(FAS)
EAI:
106822180
(FAS)
MYB:
102259838
(FAS)
MYD:
102760302
(FAS)
MNA:
107543257
(FAS)
HAI:
109377126
(FAS)
DRO:
112307358
(FAS)
PALE:
102879561
(FAS)
RAY:
107502212
(FAS)
MJV:
108392867
(FAS)
LAV:
100657715
(FAS)
TMU:
101346704
SHR:
105749219
(FAS)
PCW:
110198951
(FAS)
OAA:
103165091
(FAS)
GGA:
395274
(FAS)
MGP:
100550139
(FAS)
CJO:
107315904
(FAS)
NMEL:
110400542
(FAS)
APLA:
101796331
(FAS)
ACYG:
106030038
(FAS)
TGU:
100225721
(FAS)
LSR:
110475612
(FAS)
SCAN:
103814184
(FAS)
GFR:
102033034
(FAS)
FAB:
101806294
(FAS)
PHI:
102102426
(FAS)
PMAJ:
107206851
(FAS)
CCAE:
111930915
(FAS)
CCW:
104696515
(FAS)
ETL:
114055892
(FAS)
FPG:
101911760
(FAS)
FCH:
102048640
(FAS)
CLV:
102087399
(FAS)
EGZ:
104129042
(FAS)
NNI:
104013978
(FAS)
ACUN:
113481795
PADL:
103913942
(FAS)
AAM:
106487830
(FAS)
ASN:
102375471
(FAS)
AMJ:
102562734
(FAS)
PSS:
102463316
(FAS)
CMY:
102944566
(FAS)
CPIC:
101938109
(FAS)
ACS:
100551688
(fas)
PVT:
110083121
(FAS)
PBI:
103050181
PMUA:
114597296
(FAS)
GJA:
107121652
(FAS)
XLA:
108696050
108697171
XTR:
100124750
(fas)
DRE:
768248
(fas)
SRX:
107715957
107744555
SANH:
107670847
107689821
SGH:
107554068
107583548
CCAR:
109062099
109108031
IPU:
100304627
PHYP:
113547709
AMEX:
103046657
EEE:
113590405
TRU:
101067230
LCO:
104929632
NCC:
104956661
MZE:
101463633
ONL:
102083126
OLA:
101172757
XMA:
102232209
XCO:
114137823
PRET:
103476792
CVG:
107088506
NFU:
107376035
KMR:
108243471
(fas)
ALIM:
106535067
AOCE:
111588573
CSEM:
103387676
POV:
109631170
LCF:
108897286
(fas)
SDU:
111235178
SLAL:
111670053
HCQ:
109528779
BPEC:
110157042
110163036
MALB:
109960379
SASA:
100380364
(tnr6)
106577010
OTW:
112253033
112254547
SALP:
111952088
111978817
ELS:
105022722
SFM:
108939520
(fas)
PKI:
111853643
(fas)
LCM:
102349412
(FAS)
CMK:
103180778
(fas)
RTP:
109929457
» show all
Taxonomy
UniProt
Reference
PMID:
1713127
Authors
Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S
Title
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
Journal
Cell 66:233-43 (1991)
DOI:
10.1016/0092-8674(91)90614-5
Sequence
[hsa:
355
]
Reference
PMID:
24953023
Authors
Riccio M, Carnevale G, Cardinale V, Gibellini L, De Biasi S, Pisciotta A, Carpino G, Gentile R, Berloco PB, Brunelli R, Bastianelli C, Napoletano C, Cantafora A, Cossarizza A, Gaudio E, Alvaro D, De Pol A
Title
The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells.
Journal
J Hepatol 61:1097-105 (2014)
DOI:
10.1016/j.jhep.2014.06.016
Sequence
[hsa:
355
]
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integrated database retrieval system