KEGG   ORTHOLOGY: K04410
Entry
K04410                      KO                                     

Name
PAK2
Definition
p21-activated kinase 2 [EC:2.7.11.1]
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04660  T cell receptor signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05170  Human immunodeficiency virus 1 infection
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04410  PAK2; p21-activated kinase 2
   04012 ErbB signaling pathway
    K04410  PAK2; p21-activated kinase 2
   04014 Ras signaling pathway
    K04410  PAK2; p21-activated kinase 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04410  PAK2; p21-activated kinase 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04410  PAK2; p21-activated kinase 2
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K04410  PAK2; p21-activated kinase 2
  09158 Development and regeneration
   04360 Axon guidance
    K04410  PAK2; p21-activated kinase 2
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K04410  PAK2; p21-activated kinase 2
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04410  PAK2; p21-activated kinase 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04410  PAK2; p21-activated kinase 2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04410  PAK2; p21-activated kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04410  PAK2; p21-activated kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE20 family
   K04410  PAK2; p21-activated kinase 2
Genes
HSA: 5062(PAK2)
PTR: 460965(PAK2)
PPS: 100989051(PAK2)
GGO: 101130725(PAK2)
PON: 100439815(PAK2)
NLE: 100601244(PAK2)
MCC: 710314(PAK2)
MCF: 102115437(PAK2)
CSAB: 103242063(PAK2)
RRO: 104676374(PAK2)
RBB: 108542265(PAK2)
CJC: 100405552(PAK2)
SBQ: 101035351(PAK2)
MMU: 224105(Pak2)
MCAL: 110311434(Pak2)
MPAH: 110329559(Pak2)
RNO: 100910732 29432(Pak2)
MUN: 110553293(Pak2)
CGE: 100751503(Pak2)
NGI: 103738502(Pak2)
HGL: 101710712(Pak2)
CCAN: 109690046(Pak2)
OCU: 100009535(PAK2)
TUP: 102472173(PAK2)
CFA: 612814(PAK2)
VVP: 112913537(PAK2)
AML: 100475388(PAK2)
UMR: 103678928(PAK2)
UAH: 113253054(PAK2)
ORO: 101369067(PAK2)
ELK: 111154988
FCA: 101082845(PAK2)
PTG: 102968498(PAK2)
PPAD: 109266552(PAK2)
AJU: 106987894(PAK2)
BTA: 513673(PAK2)
BOM: 102282641(PAK2)
BBUB: 102402670(PAK2)
CHX: 102176919(PAK2)
OAS: 101123517(PAK2)
SSC: 100511837(PAK2)
CFR: 102504877(PAK2)
CDK: 105101281(PAK2)
BACU: 103005053 103006340(PAK2)
LVE: 103082256(PAK2)
OOR: 101272383(PAK2)
DLE: 111172258(PAK2)
PCAD: 102985262(PAK2)
ECB: 100060183(PAK2)
EPZ: 103559943(PAK2)
EAI: 106848316(PAK2)
MYB: 102250137(PAK2)
MYD: 102752411(PAK2)
MNA: 107527275(PAK2)
HAI: 109387639(PAK2)
DRO: 112320635(PAK2)
PALE: 102886796(PAK2)
RAY: 107505275(PAK2)
MJV: 108391169(PAK2)
LAV: 100664379(PAK2)
TMU: 101355178
MDO: 100015796(PAK2)
PCW: 110208178(PAK2)
OAA: 100075896(PAK2)
GGA: 424860(PAK2)
MGP: 100541412(PAK2)
CJO: 107317911(PAK2)
NMEL: 110397348(PAK2)
APLA: 101794632(PAK2)
ACYG: 106039215(PAK2)
TGU: 100229114(PAK2)
LSR: 110483047(PAK2)
SCAN: 103815510(PAK2)
GFR: 102034742(PAK2)
FAB: 101810304(PAK2)
PHI: 102107441(PAK2)
PMAJ: 107208951(PAK2)
CCAE: 111933722(PAK2)
CCW: 104696713(PAK2)
ETL: 114070521(PAK2)
FPG: 101910950(PAK2)
FCH: 102046818(PAK2)
CLV: 102088494(PAK2)
EGZ: 104131279(PAK2)
NNI: 104010637(PAK2)
ACUN: 113483647(PAK2)
PADL: 103915938(PAK2)
AAM: 106492613(PAK2)
ASN: 102385322(PAK2)
AMJ: 102571099(PAK2)
PSS: 102452394(PAK2)
CMY: 102943108(PAK2)
CPIC: 101946525(PAK2)
ACS: 100561625(pak2)
PVT: 110075278(PAK2)
PBI: 103051423(PAK2)
PMUR: 107294968(PAK2)
TSR: 106554254(PAK2)
PMUA: 114597726(PAK2)
GJA: 107113978(PAK2)
XLA: 108717139 399090(pak2.S)
XTR: 733718(pak2)
NPR: 108790159(PAK2)
DRE: 266749(pak2a) 325034(pak2b)
CCAR: 109105131
IPU: 108267562 108271286(pak2)
PHYP: 113532960(pak2) 113540262
AMEX: 103022965(pak2) 103038595
TRU: 101072607 101075040(pak2)
NCC: 104962686(pak2)
MZE: 101473947 101482829(pak2)
ONL: 100708502(pak2) 100710923
OLA: 101167280(pak2) 101169249
XMA: 102222129 102229449(pak2)
XCO: 114133902 114150417(pak2)
PRET: 103458433 103463803(pak2)
CVG: 107093018 107099462(pak2)
NFU: 107392096 107393427(pak2)
KMR: 108228441 108243432(pak2b)
AOCE: 111563443 111569615(pak2)
CSEM: 103376672(pak2) 103379106
POV: 109625686(pak2) 109643219
LCF: 108875038 108879127(pak2)
SDU: 111225480 111226340(pak2)
HCQ: 109517331 109532388(pak2)
MALB: 109962075(pak2)
SALP: 111972174 111975771(pak2)
ELS: 105011658(pak2) 105019806
SFM: 108927549(pak2) 108936692
PKI: 111832832(pak2) 111847400
LCM: 102367003(PAK2)
CMK: 103172733(pak2)
RTP: 109911747(pak2)
TSP: Tsp_07847
OBI: 106869191
 » show all
Reference
PMID:7744004
  Authors
Martin GA, Bollag G, McCormick F, Abo A
  Title
A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.
  Journal
EMBO J 14:1970-8 (1995)
DOI:10.1002/j.1460-2075.1995.tb07189.x
  Sequence
[hsa:5062]
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