KEGG   ORTHOLOGY: K04450Help
Entry
K04450                      KO                                     

Name
ATF2, CREBP1
Definition
cyclic AMP-dependent transcription factor ATF-2
Pathway
ko04010  MAPK signaling pathway
ko04013  MAPK signaling pathway - fly
ko04022  cGMP-PKG signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04211  Longevity regulating pathway
ko04261  Adrenergic signaling in cardiomyocytes
ko04624  Toll and Imd signaling pathway
ko04668  TNF signaling pathway
ko04714  Thermogenesis
ko04728  Dopaminergic synapse
ko04911  Insulin secretion
ko04915  Estrogen signaling pathway
ko04918  Thyroid hormone synthesis
ko04922  Glucagon signaling pathway
ko04925  Aldosterone synthesis and secretion
ko04926  Relaxin signaling pathway
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05034  Alcoholism
ko05161  Hepatitis B
ko05163  Human cytomegalovirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04013 MAPK signaling pathway - fly
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04668 TNF signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04022 cGMP-PKG signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04151 PI3K-Akt signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
 09150 Organismal Systems
  09151 Immune system
   04624 Toll and Imd signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09152 Endocrine system
   04911 Insulin secretion
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04922 Glucagon signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04915 Estrogen signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04926 Relaxin signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04935 Growth hormone synthesis, secretion and action
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04918 Thyroid hormone synthesis
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04928 Parathyroid hormone synthesis, secretion and action
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04925 Aldosterone synthesis and secretion
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04927 Cortisol synthesis and secretion
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09156 Nervous system
   04728 Dopaminergic synapse
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09149 Aging
   04211 Longevity regulating pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09159 Environmental adaptation
   04714 Thermogenesis
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09165 Substance dependence
   05030 Cocaine addiction
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05031 Amphetamine addiction
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05034 Alcoholism
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05161 Hepatitis B
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05163 Human cytomegalovirus infection
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
BRITE hierarchy
Other DBs
GO: 0035497
Genes
HSA: 1386(ATF2)
PTR: 101059354(ATF2)
PPS: 100985706(ATF2)
GGO: 101135003(ATF2)
PON: 100450554(ATF2)
NLE: 100582751(ATF2)
MCC: 699072(ATF2)
MCF: 101925838(ATF2)
CSAB: 103217363(ATF2)
RRO: 104672399(ATF2)
RBB: 108527163(ATF2)
CJC: 100414156(ATF2)
SBQ: 101035834(ATF2)
MMU: 11909(Atf2)
MCAL: 110286367(Atf2)
MPAH: 110317821(Atf2)
RNO: 81647(Atf2)
MUN: 110556579(Atf2)
CGE: 100754663(Atf2)
NGI: 103751761(Atf2)
HGL: 101717365(Atf2)
CCAN: 109689841(Atf2)
OCU: 100355367(ATF2)
TUP: 102473406(ATF2)
CFA: 478806(ATF2)
VVP: 112916383(ATF2)
AML: 100474135(ATF2)
UMR: 103659593(ATF2)
UAH: 113250749(ATF2)
ORO: 101374034(ATF2)
ELK: 111142901
FCA: 101090884(ATF2)
PTG: 102954603(ATF2)
PPAD: 109273371(ATF2)
AJU: 106988085(ATF2)
BTA: 509827(ATF2)
BOM: 102283891(ATF2)
BIU: 109566270(ATF2)
BBUB: 102410577(ATF2)
CHX: 102180634(ATF2)
OAS: 101108548(ATF2)
SSC: 100513441(ATF2)
CFR: 102512476(ATF2)
CDK: 105097571(ATF2)
BACU: 102999133(ATF2)
LVE: 103089070(ATF2)
OOR: 101276923(ATF2)
DLE: 111172890(ATF2)
PCAD: 102974369(ATF2)
ECB: 100053304(ATF2)
EPZ: 103553756(ATF2)
EAI: 106837905(ATF2)
MYB: 102241887(ATF2)
MYD: 102761389(ATF2)
MNA: 107532468(ATF2)
HAI: 109388738(ATF2)
DRO: 112305718(ATF2)
PALE: 102889014(ATF2)
RAY: 107504977(ATF2)
LAV: 100657989(ATF2)
TMU: 101359884
MDO: 100025939(ATF2)
SHR: 100914193(ATF2)
PCW: 110211588(ATF2)
OAA: 100077942(ATF2)
GGA: 395727(ATF2)
MGP: 100549420(ATF2)
CJO: 107316660(ATF2)
NMEL: 110399453(ATF2)
APLA: 101800932(ATF2)
ACYG: 106030015(ATF2)
TGU: 100226584(ATF2)
LSR: 110482896(ATF2)
SCAN: 103814449(ATF2)
GFR: 102034606(ATF2)
FAB: 101812575(ATF2)
PHI: 102105113(ATF2)
PMAJ: 107207532(ATF2)
CCAE: 111932059(ATF2)
CCW: 104693853(ATF2)
ETL: 114054885(ATF2)
FPG: 101912040(ATF2)
FCH: 102052727(ATF2)
CLV: 102084432(ATF2)
EGZ: 104128067(ATF2)
NNI: 104010014(ATF2)
ACUN: 113482190(ATF2)
PADL: 103924112(ATF2)
AAM: 106499205(ATF2)
ASN: 102387336(ATF2)
AMJ: 102572172(ATF2)
PSS: 102460331(ATF2)
CMY: 102939131(ATF2)
CPIC: 101945668(ATF2)
ACS: 100557710(atf2)
PVT: 110085213(ATF2)
PBI: 103053462(ATF2)
PMUR: 107301365(ATF2)
TSR: 106548735(ATF2)
PMUA: 114606668(ATF2) 114606722
GJA: 107123397(ATF2)
XLA: 108701386(atf2.L) 108703012 378533(atf2.S)
XTR: 100485532(atf2)
NPR: 108800395(ATF2)
DRE: 100006516(atf2) 567018(atf7b)
SGH: 107600703
IPU: 108266715(atf2)
PHYP: 113525280(atf2)
AMEX: 103028069(atf2)
EEE: 113582331(atf2)
TRU: 101063333(atf2)
LCO: 104924439(atf2)
NCC: 104965544(atf2)
MZE: 101463949(atf2)
ONL: 100699389(atf2)
OLA: 101161843(atf2)
XMA: 102234028(atf2)
XCO: 114148083(atf2)
PRET: 103458305(atf2)
CVG: 107085739(atf2)
NFU: 107390001(atf2)
KMR: 108239783(atf2)
ALIM: 106512883(atf2)
AOCE: 111577835(atf2)
CSEM: 103391862 107988055(atf2)
POV: 109631016(atf2)
LCF: 108882968(atf2)
SDU: 111218870(atf2)
SLAL: 111654625(atf2)
HCQ: 109507870(atf2)
BPEC: 110166549(atf2)
MALB: 109958112(atf2)
SASA: 106582491 106586246(atf2)
OTW: 112236821(atf2)
SALP: 111959522 111975332(atf2)
ELS: 105016218(atf2)
SFM: 108920372(atf2) 108928057
PKI: 111838634(atf2)
LCM: 102360640 102366239(ATF2)
CMK: 103176469(atf2)
RTP: 109929477(atf2)
SPU: 577426
APLC: 110984186
DME: Dmel_CG44246(Atf-2)
DER: 6548433
DSI: Dsimw501_GD11905(Dsim_GD11905)
DSR: 110184110
DPE: 6592285
DMN: 108160147
DWI: 6640182
DAZ: 108617045
DNV: 108654709
DHE: 111593910
MDE: 101890809
LCQ: 111685726
AAG: 5577542
AALB: 109432568
AME: 100576527
BIM: 100749459
BTER: 100649707
CCAL: 108632989
OBB: 114879534
SOC: 105202168
MPHA: 105839911
AEC: 105145677
ACEP: 105627948
PBAR: 105426825
VEM: 105565082
HST: 105192642
DQU: 106742046
CFO: 105249521
LHU: 105677106
PGC: 109858507
PCF: 106791946
NVI: 100119270
CSOL: 105361172
MDL: 103576287
TCA: 663103
DPA: 109539767
ATD: 109608283
NVL: 108569504
BMOR: 100862750
BMAN: 114250244
PMAC: 106715142
PRAP: 110993434
HAW: 110369623
TNL: 113499958
BTAB: 109041413
CLEC: 106663685
ZNE: 110833127
FCD: 110852191
PVM: 113822147
TUT: 107370561
DPTE: 113793654
CSCU: 111619050
PTEP: 107440184
PCAN: 112556639
CRG: 105323178
MYI: 110446621
OBI: 106878431
LAK: 106161773
EPA: 110232304
ADF: 107348901
AMIL: 114967441
PDAM: 113668572
SPIS: 111331051
DGT: 114523073
HMG: 100213904
AQU: 100632529
HBR: 110659667
APRO: F751_3120
MAW: MAC_08741
MAJ: MAA_01331
CMT: CCM_09413
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2529117
  Authors
Maekawa T, Sakura H, Kanei-Ishii C, Sudo T, Yoshimura T, Fujisawa J, Yoshida M, Ishii S
  Title
Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.
  Journal
EMBO J 8:2023-8 (1989)
  Sequence
[hsa:1386]
Reference
  Authors
Kawasaki H, Schiltz L, Chiu R, Itakura K, Taira K, Nakatani Y, Yokoyama KK
  Title
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation.
  Journal
Nature 405:195-200 (2000)
DOI:10.1038/35012097
  Sequence
[hsa:1386]
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