KEGG ORTHOLOGY: K04861

ORTHOLOGY: K04861

Entry

K04861 KO

Name

CACNA2D4

Definition

voltage-dependent calcium channel alpha-2/delta-4

Pathway

ko04010

MAPK signaling pathway

ko04260

Cardiac muscle contraction

ko04261

Adrenergic signaling in cardiomyocytes

ko04921

Oxytocin signaling pathway

ko05410

Hypertrophic cardiomyopathy

ko05412

Arrhythmogenic right ventricular cardiomyopathy

ko05414

Dilated cardiomyopathy

Disease

H00481

Cone-rod dystrophy and cone dystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
   04261 Adrenergic signaling in cardiomyocytes
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
   05414 Dilated cardiomyopathy
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4

Other DBs

GO:

0005245

TC:

8.A.18.4

Genes

HSA:	93589(CACNA2D4)

PTR:	466912(CACNA2D4)

PPS:	100973190(CACNA2D4)

GGO:	101153550(CACNA2D4)

PON:	100441103(CACNA2D4)

NLE:	100598790(CACNA2D4)

MCC:	721703(CACNA2D4)

MCF:	102131855(CACNA2D4)

CSAB:

103218378(CACNA2D4)

RRO:	104662537(CACNA2D4)

RBB:	108522308(CACNA2D4)

CJC:	100409999(CACNA2D4)

SBQ:	101038775(CACNA2D4)

MMU:	319734(Cacna2d4)

MCAL:

110295757(Cacna2d4)

MPAH:

110316341(Cacna2d4)

RNO:	312668(Cacna2d4)

MUN:	110556683(Cacna2d4)

NGI:	103739384(Cacna2d4)

HGL:	101705589(Cacna2d4)

CCAN:

109702845

OCU:	100354108(CACNA2D4)

TUP:	102472656(CACNA2D4)

CFA:	477733(CACNA2D4)

VVP:	112917422(CACNA2D4)

AML:	100480223(CACNA2D4)

UMR:	103675758(CACNA2D4)

UAH:	113258103(CACNA2D4)

ORO:	101374807(CACNA2D4)

ELK:

111159692

FCA:	101095834(CACNA2D4)

PTG:	102951140(CACNA2D4)

PPAD:

109276252(CACNA2D4)

AJU:	106965471(CACNA2D4)

BTA:	784075(CACNA2D4)

BOM:	102277012(CACNA2D4)

BIU:	109558613(CACNA2D4)

CHX:	102176592(CACNA2D4)

OAS:	101116306(CACNA2D4)

SSC:	100620898(CACNA2D4)

CFR:	102517334(CACNA2D4)

CDK:	105102927(CACNA2D4)

BACU:

103019660(CACNA2D4)

LVE:	103076342(CACNA2D4)

OOR:	101279491(CACNA2D4)

DLE:	111176547(CACNA2D4)

PCAD:

102989228(CACNA2D4)

EPZ:	103560835(CACNA2D4)

EAI:	106839431(CACNA2D4)

MYB:	102254288(CACNA2D4)

MYD:	102752991(CACNA2D4)

MNA:	107546422(CACNA2D4)

HAI:	109388949(CACNA2D4)

DRO:	112300270(CACNA2D4)

PALE:

102885883(CACNA2D4)

RAY:	107500543(CACNA2D4)

MJV:	108395652(CACNA2D4)

LAV:	100663604(CACNA2D4)

TMU:

101355114

MDO:	100021296(CACNA2D4)

SHR:

100925979

PCW:	110218752(CACNA2D4)

OAA:	100092094(CACNA2D4)

GGA:	100858946(CACNA2D4)

MGP:

100544274

CJO:	107314869(CACNA2D4)

NMEL:

110395441(CACNA2D4)

APLA:

101792163(CACNA2D4)

ACYG:

106030937(CACNA2D4)

TGU:	100224985(CACNA2D4)

LSR:	110472972(CACNA2D4)

SCAN:

103820520(CACNA2D4)

GFR:	102035174(CACNA2D4)

FAB:	101816433(CACNA2D4)

PHI:	102110049(CACNA2D4)

PMAJ:

107204208(CACNA2D4)

CCAE:

111928463(CACNA2D4)

CCW:	104692243(CACNA2D4)

ETL:	114068753(CACNA2D4)

FPG:	101919673(CACNA2D4)

FCH:	102054748(CACNA2D4)

CLV:	102089727(CACNA2D4)

EGZ:	104134401(CACNA2D4)

NNI:	104020248(CACNA2D4)

ACUN:

113491451(CACNA2D4)

PADL:

103924497(CACNA2D4)

AAM:	106488360(CACNA2D4)

ASN:	102382465(CACNA2D4)

AMJ:	106736655(CACNA2D4)

PSS:	102451307(CACNA2D4)

CMY:	102944927(CACNA2D4)

CPIC:

101946567(CACNA2D4)

ACS:	100553057(cacna2d4)

PVT:	110076680(CACNA2D4)

PBI:	103062231(CACNA2D4)

PMUR:

107294503(CACNA2D4)

TSR:

106540675

PMUA:

114604939(CACNA2D4)

GJA:	107120232(CACNA2D4)

XLA:

108704584

XTR:	100488361(cacna2d4)

NPR:	108804593(CACNA2D4)

DRE:	100150428(cacna2d4b) 568225(cacna2d4a)

SRX:	107716619 107738821 107753542

SANH:

107665717 107679611 107694142

SGH:	107574657 107590835 107591101

CCAR:

109051284 109071201 109109500

IPU:

108268693

PHYP:

113546531(cacna2d4)

AMEX:

103042398 103042404

EEE:	113576576 113586434

TRU:	101064792(cacna2d4) 101076123

TNG:	GSTEN00007786G001 GSTEN00014505G001

LCO:	104933373 104940549

MZE:	101471517 101471649

ONL:	100700975 100711833

OLA:	101171407 101173028

XMA:	102230819(cacna2d4) 102231641

XCO:	114143095 114160961(cacna2d4)

PRET:

103459273(cacna2d4) 103465652

CVG:	107093595 107095998(cacna2d4)

NFU:	107380887 107385197(cacna2d4)

KMR:	108235065(cacna2d4a) 108248114

ALIM:

106515162(cacna2d4) 106521797 106522094

AOCE:

111564040 111571445(cacna2d4)

CSEM:

103379950 103382790

POV:	109624117(cacna2d4) 109632699

LCF:	108894951 108902629

SDU:	111224495 111235963

SLAL:

111663642 111671895

HCQ:	109507929 109520039(cacna2d4)

BPEC:

110156006 110166781

MALB:

109956360

SASA:

106561009(cacna2d4) 106584529

OTW:	112218193(cacna2d4) 112260024

SALP:

111962195(cacna2d4) 111971793

ELS:	105023094(cacna2d4) 105031141

SFM:	108920806(cacna2d4)

PKI:	111843101(cacna2d4)

LCM:	102358199(CACNA2D4)

CMK:	103181799(cacna2d4)

RTP:

109930100

DME:	Dmel_CG42817(Ca-Ma2d)

DER:

6543385

DSE:

6613670

DSI:	Dsimw501_GD24043(Dsim_GD24043)

DYA:	Dyak_GE21365

DAN:

6497756

DSR:

110185653

DPO:	Dpse_GA11645

DPE:

6598123

DMN:

108161672

DWI:

6643725

DGR:	Dgri_GH10400

DMO:	Dmoj_GI17380

DAZ:

DNV:

DHE:

DVI:

MDE:

LCQ:

AGA:	AgaP_AGAP009579

AAG:

5574272

AALB:

109400990 115257438 115257543

CQU:	CpipJ_CPIJ001793

AME:

100577376

BIM:	100741020 100745808

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:	105143903 105148758

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:	109594880 109608335

NVL:

108567086

BMOR:

101746536

BMAN:

114246298

DPL:	KGM_215642

PMAC:

106709294 106709316

PRAP:

111003820 111003879

HAW:	110377785 110378557

TNL:	113501665 113502213

PXY:

105397612

API:

100164032

DNX:	107168932 107173920

AGS:	114119786 114121293

RMD:	113550132 113558909

BTAB:

109036948

CLEC:

106664727 106673486

PHU:	Phum_PHUM308320

ZNE:

CRG:

AQU:

Reference

PMID:12181424

Authors

Qin N, Yagel S, Momplaisir ML, Codd EE, D'Andrea MR

Title

Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.

Journal

Mol Pharmacol 62:485-96 (2002)
DOI:10.1124/mol.62.3.485

Sequence

[hsa:93589]

LinkDB

DBGET integrated database retrieval system