KEGG   ORTHOLOGY: K05060Help
Entry
K05060                      KO                                     

Name
IL6ST, GP130, CD130
Definition
interleukin 6 signal transducer
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04630  JAK-STAT signaling pathway
ko04659  Th17 cell differentiation
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
   05203 Viral carcinogenesis
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
   04090 CD molecules
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
CD molecules [BR:ko04090]
 Proteins
  K05060  CD130, IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor)
BRITE hierarchy
Other DBs
GO: 0004915
Genes
HSA: 3572(IL6ST)
PTR: 461866(IL6ST)
PPS: 100992032(IL6ST)
GGO: 101153224(IL6ST)
PON: 100451191(IL6ST)
NLE: 100581824(IL6ST)
MCC: 574127(IL6ST)
MCF: 101926138(IL6ST)
CSAB: 103221611(IL6ST)
RRO: 104680478(IL6ST)
RBB: 108530957(IL6ST)
CJC: 100396729(IL6ST)
SBQ: 101029979(IL6ST)
MMU: 16195(Il6st)
MCAL: 110307804(Il6st)
MPAH: 110328878(Il6st)
RNO: 25205(Il6st)
MUN: 110546647(Il6st)
CGE: 100767181(Il6st)
NGI: 103739911(Il6st)
HGL: 101703833(Il6st)
CCAN: 109700609(Il6st)
OCU: 100349330(IL6ST)
TUP: 102494199(IL6ST)
CFA: 403545(IL6ST)
VVP: 112935199(IL6ST)
AML: 100483131(IL6ST)
UMR: 103663669(IL6ST)
UAH: 113255323(IL6ST)
ORO: 101368221(IL6ST)
ELK: 111156948
FCA: 101089832(IL6ST)
PTG: 102968948(IL6ST)
PPAD: 109246341(IL6ST)
AJU: 106975253(IL6ST)
BTA: 522155(IL6ST)
BOM: 102280532(IL6ST)
BIU: 109574817(IL6ST)
BBUB: 102405590(IL6ST)
CHX: 102188086(IL6ST)
OAS: 101113174(IL6ST)
SSC: 100037294(IL6ST)
CFR: 102511873 102515275(IL6ST)
CDK: 105087138(IL6ST)
BACU: 103000073(IL6ST)
LVE: 103075698(IL6ST)
OOR: 101287401(IL6ST)
DLE: 111186578(IL6ST)
PCAD: 102982237(IL6ST)
ECB: 100051700(IL6ST)
EPZ: 103548204(IL6ST)
EAI: 106843367(IL6ST)
MYB: 102253606(IL6ST)
MYD: 102763204(IL6ST)
MNA: 107527134(IL6ST)
HAI: 109382150(IL6ST)
DRO: 112315251(IL6ST)
PALE: 102880415(IL6ST)
RAY: 107509633(IL6ST) 107518627
MJV: 108386768 108393228(IL6ST)
LAV: 100669556(IL6ST)
TMU: 101353064
MDO: 100017284(IL6ST)
SHR: 100913307(IL6ST) 100914111
PCW: 110215675(IL6ST)
OAA: 100073530(IL6ST)
GGA: 395684(IL6ST)
MGP: 100550313
CJO: 107305990(IL6ST)
NMEL: 110389606(IL6ST)
APLA: 101799928(IL6ST)
ACYG: 106035611(IL6ST)
TGU: 100226842(IL6ST)
LSR: 110472554(IL6ST)
SCAN: 103821034(IL6ST)
GFR: 102036418(IL6ST)
FAB: 101807050(IL6ST)
PHI: 102107918(IL6ST)
PMAJ: 107198202(IL6ST)
CCAE: 111941441(IL6ST)
CCW: 104686676(IL6ST)
ETL: 114065911(IL6ST)
FPG: 101911352(IL6ST)
FCH: 102051353(IL6ST)
CLV: 102094030(IL6ST)
EGZ: 104134682(IL6ST)
NNI: 104013731(IL6ST) 104014605
ACUN: 113489579(IL6ST)
PADL: 103919426(IL6ST)
ASN: 102376353(IL6ST)
AMJ: 102559273(IL6ST)
PSS: 102460174(IL6ST)
CMY: 102933394(IL6ST)
CPIC: 101932922(IL6ST) 101952357
ACS: 100562134(il6st)
PVT: 110079290 110085393(IL6ST)
PMUR: 107294972(IL6ST) 107300506
TSR: 106546253(IL6ST)
GJA: 107113291 107120496(IL6ST)
XLA: 100158347(il6st.L) 100174791(il6st.S)
XTR: 100489642(il6st)
NPR: 108792012(IL6ST)
DRE: 100006778(il6st)
PHYP: 113543547
TRU: 101064175(il6st)
NCC: 104952060
XMA: 102219847(il6st) 102226847
XCO: 114134540 114149108(il6st)
PRET: 103458450 103473124(il6st)
CVG: 107084616 107102482(il6st)
CSEM: 103381225 103389161(il6st)
POV: 109636341 109643155(il6st)
SDU: 111221084(il6st) 111238541
HCQ: 109530464(il6st)
MALB: 109957337 109960748(il6st)
ELS: 105013144 105021723(il6st)
SFM: 108921565 108929965(il6st)
PKI: 111834479(il6st) 111836578
LCM: 102356131 102357816(IL6ST)
CIN: 100135649(gp130-like)
MYI: 110463908
LAK: 106151265
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2261637
  Authors
Hibi M, Murakami M, Saito M, Hirano T, Taga T, Kishimoto T
  Title
Molecular cloning and expression of an IL-6 signal transducer, gp130.
  Journal
Cell 63:1149-57 (1990)
DOI:10.1016/0092-8674(90)90411-7
  Sequence
[hsa:3572]
LinkDB All DBs

DBGET integrated database retrieval system