KEGG   ORTHOLOGY: K05072Help
Entry
K05072                      KO                                     

Name
IL7R, CD127
Definition
interleukin 7 receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04068  FoxO signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
ko05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04068 FoxO signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04151 PI3K-Akt signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05072  IL7R, CD127; interleukin 7 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05072  IL7R, CD127; interleukin 7 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05072  IL7R, CD127; interleukin 7 receptor
  09163 Immune disease
   05340 Primary immunodeficiency
    K05072  IL7R, CD127; interleukin 7 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05072  IL7R, CD127; interleukin 7 receptor
   04090 CD molecules
    K05072  IL7R, CD127; interleukin 7 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05072  IL7R, CD127; interleukin 7 receptor
CD molecules [BR:ko04090]
 Proteins
  K05072  CD127, IL7R; interleukin 7 receptor
BRITE hierarchy
Other DBs
GO: 0004917
Genes
HSA: 3575(IL7R)
PTR: 461922(IL7R)
PPS: 100981232(IL7R)
GGO: 101140372(IL7R)
PON: 100461835(IL7R)
NLE: 100583768(IL7R)
MCC: 699869(IL7R)
MCF: 102143679(IL7R)
CSAB: 103215123(IL7R)
RRO: 104662030(IL7R)
RBB: 108533533(IL7R)
CJC: 100397720(IL7R)
SBQ: 101044161(IL7R)
MMU: 16197(Il7r)
MCAL: 110310926(Il7r)
MPAH: 110329173(Il7r)
RNO: 294797(Il7r)
MUN: 110542896(Il7r)
CGE: 100757700(Il7r)
NGI: 103741311(Il7r)
HGL: 101710077(Il7r)
CCAN: 109698833(Il7r)
OCU: 100343726(IL7R)
TUP: 102499643(IL7R)
CFA: 612582(IL7R)
VVP: 112933551(IL7R)
AML: 100477617(IL7R)
UMR: 103664716(IL7R)
UAH: 113260884(IL7R)
ORO: 101385299(IL7R)
ELK: 111141253
FCA: 101100697(IL7R)
PTG: 102953956(IL7R)
PPAD: 109267711(IL7R)
AJU: 106979009(IL7R)
BTA: 521554(IL7R)
BOM: 102284629(IL7R)
BIU: 109575020(IL7R)
BBUB: 102400952(IL7R)
CHX: 102175248(IL7R)
OAS: 101111126(IL7R)
SSC: 100271930(IL7R)
CFR: 102515501(IL7R)
CDK: 105087002(IL7R)
BACU: 103010049(IL7R)
LVE: 103089375(IL7R)
OOR: 101275057(IL7R)
DLE: 111187554(IL7R)
PCAD: 102992873(IL7R)
ECB: 100034169(IL7R)
EPZ: 103545416(IL7R)
EAI: 106824753(IL7R)
MYB: 102264253(IL7R)
MYD: 102772772(IL7R)
MNA: 107546370(IL7R)
HAI: 109376825(IL7R)
DRO: 112321141(IL7R)
PALE: 102889092(IL7R)
RAY: 107509706(IL7R)
MJV: 108406858(IL7R)
LAV: 100671266(IL7R)
TMU: 101351100
MDO: 100020565(IL7R)
SHR: 100915478(IL7R)
PCW: 110214720(IL7R)
OAA: 100078445(IL7R)
GGA: 426054(IL7R)
MGP: 100542453(IL7R)
CJO: 107305872(IL7R)
NMEL: 110389974(IL7R)
APLA: 101800042(IL7R)
ACYG: 106036382(IL7R)
TGU: 100226205(IL7R)
LSR: 110482656(IL7R)
SCAN: 103821063(IL7R)
GFR: 102033898(IL7R)
FAB: 101816330(IL7R)
PHI: 102109259(IL7R)
PMAJ: 107216341(IL7R)
CCAE: 111940971(IL7R)
CCW: 104686602(IL7R)
ETL: 114066153(IL7R)
FPG: 101911430(IL7R)
FCH: 102052979(IL7R)
CLV: 102085807(IL7R)
EGZ: 104133924(IL7R)
NNI: 104018643(IL7R)
ACUN: 113489797(IL7R)
PADL: 103921479(IL7R)
AAM: 106499523(IL7R)
ASN: 102368640(IL7R)
AMJ: 102558184(IL7R)
PSS: 102449770(IL7R)
CMY: 102932302(IL7R)
CPIC: 101937386(IL7R)
ACS: 103279695(il7r)
PVT: 110080088(IL7R)
PBI: 103058565(IL7R)
PMUR: 107297967(IL7R)
TSR: 106551942(IL7R)
PMUA: 114606663(IL7R)
GJA: 107108287(IL7R)
DRE: 100134973(il7r)
IPU: 108279371(il7r)
PHYP: 113541790(il7r)
AMEX: 103047579(il7r)
EEE: 113573243(il7r)
TRU: 101078727(il7r)
LCO: 104936386(il7r)
MZE: 101477974(il7r)
ONL: 102082329(il7r)
OLA: 110013505(il7r)
XMA: 102218066(il7r)
XCO: 114150235(il7r)
PRET: 103474046
CVG: 107095097(il7r)
NFU: 107374989(il7r)
KMR: 108245570(il7r)
ALIM: 106527579
CSEM: 103390387
SDU: 111238700(il7r)
SLAL: 111652916(il7r)
HCQ: 109523342(il7r)
BPEC: 110161723(il7r)
MALB: 109973109(il7r)
OTW: 112219510 112257526(il7r)
SALP: 111961414 111982155(il7r)
ELS: 105014762(il7r)
SFM: 108932322(il7r)
PKI: 111842105
RTP: 109926598(il7r)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2317865
  Authors
Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al.
  Title
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
  Journal
Cell 60:941-51 (1990)
DOI:10.1016/0092-8674(90)90342-C
  Sequence
[hsa:3575]
Reference
PMID:8266077
  Authors
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ
  Title
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.
  Journal
Science 262:1877-80 (1993)
DOI:10.1126/science.8266077
LinkDB All DBs

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