KEGG ORTHOLOGY: K05097

ORTHOLOGY: K05097

Entry

K05097 KO

Name

FLT4, VEGFR3

Definition

FMS-like tyrosine kinase 4 [EC:2.7.10.1]

Pathway

ko04010

MAPK signaling pathway

ko04014

Ras signaling pathway

ko04015

Rap1 signaling pathway

ko04020

Calcium signaling pathway

ko04151

PI3K-Akt signaling pathway

ko04510

Focal adhesion

ko05200

Pathways in cancer

ko05224

Breast cancer

Disease

H00535

Hereditary lymphedema

H01471

Lymphangioma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
   04014 Ras signaling pathway
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
   04015 Rap1 signaling pathway
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
   04020 Calcium signaling pathway
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
   04151 PI3K-Akt signaling pathway
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
  09162 Cancer: specific types
   05224 Breast cancer
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4
Protein kinases [BR:ko01001]
Receptor tyrosine kinases (RTK)
  VEGFR family [OT]
   K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4

Genes

HSA:	2324(FLT4)

PTR:	462339(FLT4)

PPS:	100969442(FLT4)

GGO:	101130379(FLT4)

PON:	100462098(FLT4)

NLE:	100582920(FLT4)

MCC:	716412(FLT4)

MCF:	102123168(FLT4)

CSAB:

103245125(FLT4)

RRO:	104671523(FLT4)

RBB:	108514173(FLT4)

CJC:	100388404(FLT4)

SBQ:	101033672(FLT4)

MMU:	14257(Flt4)

MCAL:

110304471(Flt4)

MPAH:

110331550(Flt4)

RNO:	114110(Flt4)

MUN:	110547372(Flt4)

CGE:	100766609(Flt4)

NGI:	103749361(Flt4)

HGL:	101702013(Flt4)

CCAN:

109700252(Flt4)

OCU:	100008829(FLT4)

TUP:	102482918(FLT4)

CFA:	481464(FLT4)

VVP:	112911875(FLT4)

AML:	100478767(FLT4)

UMR:	103680018(FLT4)

UAH:	113261544(FLT4)

ORO:	101382368(FLT4)

ELK:

111158898

FCA:	101094727(FLT4)

PTG:	102960922(FLT4)

PPAD:

109278978(FLT4)

AJU:	106970218(FLT4)

BTA:	338031(FLT4)

BOM:	102267985(FLT4)

BIU:	109561327(FLT4)

BBUB:

102402057(FLT4)

CHX:	102180480(FLT4)

OAS:	101117247(FLT4)

SSC:	100518179(FLT4)

CFR:	102504702(FLT4)

CDK:	105100622(FLT4)

BACU:

103004554(FLT4)

LVE:	103074358(FLT4)

OOR:	101272910(FLT4)

DLE:	111170902(FLT4)

PCAD:

102988868(FLT4)

ECB:	100066773(FLT4)

EPZ:	103566205(FLT4)

EAI:	106843734(FLT4)

MYB:	102244912(FLT4)

MYD:	102756633(FLT4)

MNA:	107528437(FLT4)

HAI:	109392740(FLT4)

DRO:	112296393(FLT4)

PALE:

102889771(FLT4)

RAY:	107512332(FLT4)

MJV:	108408755(FLT4)

LAV:	100677038(FLT4)

TMU:

101340931

MDO:	100032078(FLT4)

SHR:	100932306(FLT4)

PCW:	110216702(FLT4)

OAA:	100087557(FLT4)

GGA:	395742(FLT4)

MGP:	100543111(FLT4)

CJO:	107320206(FLT4)

NMEL:

110405266(FLT4)

APLA:

101790164(FLT4)

ACYG:

106032675(FLT4)

TGU:	100218470(FLT4)

LSR:	110482723(FLT4)

SCAN:

103817296(FLT4)

GFR:	102039974(FLT4)

FAB:	101808166(FLT4)

PHI:	102110772(FLT4)

PMAJ:

107210757(FLT4)

CCAE:

111935550(FLT4)

CCW:	104689586(FLT4)

ETL:	114063191(FLT4)

FPG:	101918084(FLT4)

FCH:	102053583(FLT4)

CLV:	102090209(FLT4)

EGZ:	104123344(FLT4)

NNI:	104014191(FLT4)

ACUN:

113485325(FLT4)

PADL:

103915749(FLT4)

AAM:	106493463(FLT4)

ASN:	102373975(FLT4)

AMJ:	102567838(FLT4)

PSS:	102459372(FLT4)

CMY:	102944420(FLT4)

CPIC:

101942381(FLT4)

ACS:	100556373(flt4)

PVT:	110073488(FLT4)

PBI:

103068185

PMUR:

107296517(FLT4)

TSR:	106538654(FLT4)

PMUA:

114591336(FLT4)

GJA:	107110308(FLT4)

XLA:	108710830 108712628

XTR:	100493801(flt4)

NPR:	108785383(FLT4)

DRE:	30121(flt4)

SRX:	107706735 107712307

SANH:

107660442 107679111

SGH:	107550990 107558038

CCAR:

109063756 109102888

IPU:	108268674(flt4)

PHYP:

113542868(flt4)

AMEX:

103037902

EEE:	113576525(flt4)

TRU:	101079004(flt4)

TNG:	GSTEN00017100G001

LCO:	104930066(flt4)

NCC:

104959310

MZE:	101463681(flt4)

ONL:	100711033(flt4)

OLA:	100335137(flt4)

XMA:	102233039(flt4)

XCO:	114139113(flt4)

PRET:

103471109(flt4)

CVG:	107093459(flt4)

NFU:	107385122(flt4)

KMR:	108242065(flt4)

ALIM:

106515980(flt4)

AOCE:

111578770(flt4)

CSEM:

103391112(flt4)

POV:	109624596(flt4)

LCF:	108882862(flt4)

SDU:	111226519(flt4)

SLAL:

111652030(flt4)

HCQ:	109515935(flt4)

BPEC:

110163041(flt4)

MALB:

109968381

SASA:

106612321

ELS:	105026780(flt4)

SFM:	108930359(flt4)

PKI:	111857710(flt4)

LCM:	102359993(FLT4)

CMK:	103188224(flt4)

RTP:	109927679(flt4)

OBB:

AEC:

SPIS:

Reference

PMID:1319394

Authors

Galland F, Karamysheva A, Mattei MG, Rosnet O, Marchetto S, Birnbaum D

Title

Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene.

Journal

Genomics 13:475-8 (1992)
DOI:10.1016/0888-7543(92)90277-Y

Sequence

[hsa:2324]

LinkDB

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