KEGG   ORTHOLOGY: K05434Help
Entry
K05434                      KO                                     

Name
IL21
Definition
interleukin 21
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04630  JAK-STAT signaling pathway
ko04659  Th17 cell differentiation
ko05321  Inflammatory bowel disease (IBD)
Disease
H00088  Common variable immunodeficiency
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K05434  IL21; interleukin 21
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05434  IL21; interleukin 21
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K05434  IL21; interleukin 21
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    K05434  IL21; interleukin 21
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05434  IL21; interleukin 21
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05434  IL21; interleukin 21
BRITE hierarchy
Other DBs
GO: 0001531
Genes
HSA: 59067(IL21)
PTR: 471295(IL21)
PPS: 100984436(IL21)
GGO: 101133146(IL21)
PON: 100455621(IL21)
NLE: 100591664(IL21)
MCC: 708125(IL21)
MCF: 102130762(IL21)
CSAB: 103236210(IL21)
RRO: 104661749(IL21)
RBB: 108515583(IL21)
CJC: 100386141(IL21)
SBQ: 101029390(IL21)
MMU: 60505(Il21)
MCAL: 110291773(Il21)
MPAH: 110320935(Il21)
RNO: 365769(Il21)
MUN: 110545880(Il21)
CGE: 100755479(Il21)
NGI: 103746950(Il21)
HGL: 101720915(Il21)
CCAN: 109692012(Il21)
OCU: 100344172(IL21)
TUP: 102478178(IL21)
CFA: 442935(IL21)
VVP: 112933640(IL21)
AML: 100480614(IL21)
UMR: 103661805(IL21)
UAH: 113255465(IL21)
ORO: 101385902(IL21)
FCA: 101087399(IL21)
PTG: 102956388(IL21)
AJU: 106977093(IL21)
BTA: 378475(IL21)
BOM: 102285740(IL21)
BIU: 109571034(IL21)
BBUB: 102395107(IL21)
PHD: 102321488(IL21)
CHX: 100861248(IL21)
OAS: 100862657(IL21)
SSC: 403123(IL21)
CFR: 102515160(IL21)
CDK: 105093665(IL21)
BACU: 103017608(IL21)
LVE: 103084127
OOR: 101274894(IL21)
DLE: 111186103(IL21)
PCAD: 102990393(IL21)
ECB: 100063803(IL21)
EPZ: 103557875(IL21)
EAI: 106834089(IL21)
MYB: 102261365(IL21)
MYD: 102763101(IL21)
MNA: 107529740(IL21)
HAI: 109374209(IL21)
RSS: 109452458(IL21)
DRO: 112312207(IL21)
PALE: 102895772(IL21)
RAY: 107505384(IL21)
LAV: 100656684(IL21)
TMU: 101360445
SHR: 105751011(IL21)
PCW: 110222957(IL21)
OAA: 114815477(IL21)
GGA: 554218(IL21)
MGP: 100550694(IL21)
CJO: 107313576(IL21)
APLA: 101794729(IL21)
ACYG: 106042431(IL21)
TGU: 100223945(IL21)
SCAN: 103821433
GFR: 102035531(IL21)
FAB: 101807374(IL21)
CCW: 104693711(IL21)
ETL: 114061103(IL21)
CLV: 102091768(IL21)
NNI: 104019142(IL21)
ACUN: 113479458(IL21)
AAM: 106491934(IL21)
AMJ: 109284804(IL21)
PVT: 110072830(IL21)
XLA: 108696476
XTR: 100145684(il21)
DRE: 100150203(il21)
CCAR: 109093595
PHYP: 113530157
AMEX: 111191281(il21)
TRU: 654314(il-21)
MZE: 105940966
LCF: 108901512
SDU: 111232744(il21)
HCQ: 109529047
SASA: 106604597(IL21A) 106611666(il21)
PKI: 111832813(il15)
LCM: 102365373(IL21)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D
  Title
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
  Journal
Nature 408:57-63 (2000)
DOI:10.1038/35040504
  Sequence
[hsa:59067]
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