KEGG ORTHOLOGY: K05456

ORTHOLOGY: K05456

Entry

K05456 KO

Name

NRG2

Definition

neuregulin 2

Pathway

ko01521

EGFR tyrosine kinase inhibitor resistance

ko04012

ErbB signaling pathway

ko05014

Amyotrophic lateral sclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K05456  NRG2; neuregulin 2
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K05456  NRG2; neuregulin 2
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05456  NRG2; neuregulin 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05456  NRG2; neuregulin 2
Cytokines and growth factors [BR:ko04052]
Growth factors
  Growth factors (RTK binding)
   K05456  NRG2; neuregulin 2

Genes

HSA:	9542(NRG2)

PTR:	100613749(NRG2)

PPS:	100983169(NRG2)

GGO:	101152152(NRG2)

PON:	100432995(NRG2)

NLE:	100582376(NRG2)

MCC:	694995(NRG2)

MCF:	102115529(NRG2)

CSAB:

103244652(NRG2)

RRO:	104681858(NRG2)

RBB:	108530822(NRG2)

CJC:	100391893(NRG2)

SBQ:	101034338(NRG2)

MMU:	100042150(Nrg2)

MCAL:

110284594(Nrg2)

MPAH:

110333131(Nrg2)

RNO:	432361(Nrg2)

MUN:	110564250(Nrg2)

CGE:	100759245(Nrg2)

NGI:	103743077(Nrg2)

HGL:	101696461(Nrg2)

CCAN:

109689170(Nrg2)

OCU:	100345149(NRG2)

TUP:	102480748(NRG2)

CFA:	487158(NRG2)

VVP:	112907923(NRG2)

AML:	100468215(NRG2)

UMR:	103663941(NRG2)

UAH:	113261814(NRG2)

ORO:	101382220(NRG2)

ELK:

111141189

FCA:	101090986(NRG2)

PTG:	102950253(NRG2)

PPAD:

109252159(NRG2)

AJU:	106968457(NRG2)

BTA:	783452(NRG2)

BOM:	102269655(NRG2)

BIU:	109562087(NRG2)

BBUB:

102408146(NRG2)

CHX:	102185177(NRG2)

OAS:	101121348(NRG2)

SSC:	100625643(NRG2)

CFR:	102510636(NRG2)

CDK:	105098149(NRG2)

BACU:

103005049(NRG2)

LVE:	103069299(NRG2)

OOR:	101274058(NRG2)

DLE:	111182522(NRG2)

PCAD:

102979225(NRG2)

ECB:	100072444(NRG2)

EPZ:	103548027(NRG2)

EAI:	106834540(NRG2)

MYB:	102263775(NRG2)

MYD:	102769251(NRG2)

MNA:	107537999(NRG2)

HAI:	109393067(NRG2)

DRO:	112318032(NRG2)

PALE:

102893043(NRG2)

RAY:	107521551(NRG2)

MJV:	108394742(NRG2)

LAV:	100670957(NRG2)

TMU:

101343709

MDO:	100020721(NRG2)

SHR:	100932924(NRG2)

PCW:	110220878(NRG2)

OAA:	100084685(NRG2)

GGA:	427606(NRG2)

MGP:	100548763(NRG2)

CJO:	107320425(NRG2)

NMEL:

110405232(NRG2)

APLA:

101799535(NRG2)

ACYG:

106042742(NRG2)

TGU:	100219062(NRG2)

LSR:	110471318(NRG2)

SCAN:

103817451(NRG2)

GFR:	102032122(NRG2)

FAB:	101815225(NRG2)

PHI:	102107111(NRG2)

PMAJ:

107210770(NRG2)

CCAE:

111935665(NRG2)

CCW:	104693519(NRG2)

ETL:	114059777(NRG2)

FPG:	101922897(NRG2)

FCH:	102053051(NRG2)

CLV:	102095137(NRG2)

EGZ:	104135799(NRG2)

NNI:	104008914(NRG2)

ACUN:

113485128(NRG2)

PADL:

103915465(NRG2)

AAM:	106494304(NRG2)

ASN:	102372853(NRG2)

AMJ:	102574595(NRG2)

PSS:	102453280(NRG2)

CMY:	102931907(NRG2)

ACS:	100567258(nrg2)

PVT:	110082124(NRG2)

PBI:	103067704(NRG2)

PMUR:

107284140(NRG2)

TSR:

106553384

PMUA:

114601165(NRG2)

GJA:	107117577(NRG2)

DRE:	100006951(nrg2a) 100270726(nrg2b)

SRX:	107715407 107718490 107733500 107758519

SANH:

107660158 107660787 107684713 107693753

SGH:	107557058 107559265 107560662 107589101

CCAR:

109050150 109070412

IPU:	108268830 108278884(nrg2)

PHYP:

113529238 113541544(nrg2)

AMEX:

103028723(nrg2) 103042778

EEE:	113573372 113585259

TRU:	101064785(nrg2) 101075752

TNG:	GSTEN00008062G001 GSTEN00019001G001

LCO:	104920612 104936498

NCC:	104942308 104961721

MZE:	101470250 101480242

ONL:	100698076 100711745

OLA:	101159516 101164582

XMA:	102218549 102236685

XCO:	114139377 114152930(nrg2)

PRET:

103471045(nrg2) 103475452

CVG:	107089813 107090144

NFU:	107380938 107386388(nrg2)

KMR:	108236992(nrg2a) 108238002(nrg2b)

ALIM:

106514056(nrg2) 106530431

AOCE:

111567122 111567601

CSEM:

103391295 103395784(nrg2)

POV:	109627165 109628676

LCF:	108878723 108893435

SDU:	111226777(nrg2) 111234371

SLAL:

111646448 111666218

HCQ:	109517841(nrg2) 109524274

BPEC:

110153941 110158626

MALB:

109957536 109959444

SASA:

106563662 106602814 106603019 106604398 106612118(nrg2)

OTW:	112221178 112228970 112231183

SALP:

111950969 111964335 111965963 111967248

ELS:	105010904(nrg2) 105026741

SFM:	108922971 108934070

PKI:	111836369 111853009(nrg2)

LCM:	102365318(NRG2)

CMK:	103186464(nrg2)

RTP:

109912652

BFO:

118412562

CIN:

100182295

HRO:	HELRODRAFT_167059

CRG:

OBI:

LAK:

Reference

PMID:9348101

Authors

Higashiyama S, Horikawa M, Yamada K, Ichino N, Nakano N, Nakagawa T, Miyagawa J, Matsushita N, Nagatsu T, Taniguchi N, Ishiguro H

Title

A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4.

Journal

J Biochem 122:675-80 (1997)
DOI:10.1093/oxfordjournals.jbchem.a021806

Sequence

[hsa:9542]

LinkDB

DBGET integrated database retrieval system