KEGG   ORTHOLOGY: K05460
Entry
K05460                      KO                                     

Name
HGF
Definition
hepatocyte growth factor
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko05144  Malaria
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05211  Renal cell carcinoma
ko05218  Melanoma
ko05223  Non-small cell lung cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00048  Hepatocellular carcinoma
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05460  HGF; hepatocyte growth factor
   04014 Ras signaling pathway
    K05460  HGF; hepatocyte growth factor
   04015 Rap1 signaling pathway
    K05460  HGF; hepatocyte growth factor
   04020 Calcium signaling pathway
    K05460  HGF; hepatocyte growth factor
   04151 PI3K-Akt signaling pathway
    K05460  HGF; hepatocyte growth factor
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05460  HGF; hepatocyte growth factor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05460  HGF; hepatocyte growth factor
   05205 Proteoglycans in cancer
    K05460  HGF; hepatocyte growth factor
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K05460  HGF; hepatocyte growth factor
   05226 Gastric cancer
    K05460  HGF; hepatocyte growth factor
   05218 Melanoma
    K05460  HGF; hepatocyte growth factor
   05211 Renal cell carcinoma
    K05460  HGF; hepatocyte growth factor
   05223 Non-small cell lung cancer
    K05460  HGF; hepatocyte growth factor
  09174 Infectious disease: parasitic
   05144 Malaria
    K05460  HGF; hepatocyte growth factor
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05460  HGF; hepatocyte growth factor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05460  HGF; hepatocyte growth factor
   00536 Glycosaminoglycan binding proteins
    K05460  HGF; hepatocyte growth factor
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K05460  HGF; hepatocyte growth factor
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K05460  HGF; hepatocyte growth factor
Other DBs
GO: 0005171
Genes
HSA: 3082(HGF)
PTR: 463503(HGF)
PPS: 100983117(HGF)
GGO: 101127877(HGF)
PON: 100462115(HGF)
NLE: 100586296(HGF)
MCC: 708316(HGF)
MCF: 102133907(HGF)
CSAB: 103226643(HGF)
RRO: 104681576(HGF)
RBB: 108536940(HGF)
CJC: 100385966(HGF)
SBQ: 101045517(HGF)
MMU: 15234(Hgf)
MCAL: 110294216(Hgf)
MPAH: 110316234(Hgf)
RNO: 24446(Hgf)
MUN: 110565312(Hgf)
CGE: 100764472(Hgf)
NGI: 103730723(Hgf)
HGL: 101707056(Hgf)
OCU: 100316908(HGF)
TUP: 102483689(HGF)
CFA: 403441(HGF)
VVP: 112925397(HGF)
AML: 100463560(HGF)
UMR: 103658669(HGF)
UAH: 113259246(HGF)
ORO: 101373766(HGF)
ELK: 111155271
FCA: 493705(HGF)
PTG: 102952318(HGF)
PPAD: 109268152(HGF)
AJU: 106975661(HGF)
BTA: 282879(HGF)
BOM: 102267837(HGF)
BIU: 109557878(HGF)
BBUB: 102406209(HGF)
CHX: 102183288(HGF)
OAS: 443075(HGF)
SSC: 100525120(HGF)
CFR: 102515749(HGF)
CDK: 105100369(HGF)
BACU: 102997605
LVE: 103079072(HGF)
OOR: 101273491(HGF)
DLE: 111164604(HGF)
PCAD: 102992196(HGF)
ECB: 100049848(HGF)
EPZ: 103563173(HGF)
EAI: 106840178(HGF)
MYB: 102259449(HGF)
MYD: 102765945(HGF)
MNA: 107527167(HGF)
HAI: 109392334(HGF)
DRO: 112301961(HGF)
PALE: 102884470(HGF)
RAY: 107501285(HGF)
MJV: 108399212(HGF)
LAV: 100665493(HGF)
TMU: 101344799
MDO: 100016122(HGF)
SHR: 100915696(HGF)
PCW: 110206952(HGF)
OAA: 100074892(HGF)
GGA: 395941(HGF)
MGP: 100542153(HGF)
CJO: 107321440(HGF)
NMEL: 110392449(HGF)
APLA: 101793664(HGF)
ACYG: 106035566(HGF)
TGU: 100218784(HGF)
LSR: 110469773(HGF)
SCAN: 103813737(HGF)
GFR: 102042539(HGF)
FAB: 101810717(HGF)
PHI: 102106058(HGF)
PMAJ: 107205229(HGF)
CCAE: 111923284 111923285(HGF)
CCW: 104686934(HGF)
ETL: 114058724(HGF)
FPG: 101917184(HGF)
FCH: 102052167(HGF)
CLV: 102084988(HGF)
EGZ: 104132389(HGF)
NNI: 104010752(HGF)
ACUN: 113491250(HGF)
PADL: 103920599(HGF)
AAM: 106485602(HGF)
ASN: 102385607(HGF)
AMJ: 102564574(HGF)
PSS: 102451409(HGF)
CMY: 102929769(HGF)
CPIC: 101946945(HGF)
ACS: 100566618(hgf)
PVT: 110077194(HGF)
PBI: 103063662
PMUR: 107297173
TSR: 106554702
PMUA: 114605154(HGF)
GJA: 107110492(HGF)
XLA: 108711206(hgf.L) 108713062(hgf.S)
XTR: 100495840(hgf)
NPR: 108792728(HGF)
DRE: 100334116 493781(hgfa)
SRX: 107723941 107732993 107738418 107738831
SANH: 107672595 107673134 107695871 107699067
SGH: 107557293 107559839 107563412 107591310
CCAR: 109081813 109108309 109108837
IPU: 108264660(HGF)
PHYP: 113534821(hgf)
AMEX: 103033838 103045938
EEE: 113577168 113588284
TRU: 101064315 101078862
TNG: GSTEN00020823G001 GSTEN00035532G001
LCO: 104918123(hgf) 104918795
NCC: 104952156(hgf) 104958230
MZE: 101470516(hgf) 101486965
ONL: 100704765(hgf) 100704875
OLA: 101156453 101167035(hgf)
XMA: 102226489(hgf) 102232629
XCO: 114136644(hgf) 114161125
PRET: 103459222 103466001(hgf)
CVG: 107085972 107089218
NFU: 107385652 107388871(hgf)
KMR: 108229905 108235047(hgfa)
ALIM: 106514764 106520334(hgf)
AOCE: 111563989 111564882(hgf)
CSEM: 103380100(hgf) 103382777
POV: 109624365(hgf) 109632742
LCF: 108875155 108879648
SDU: 111224573 111228480(hgf)
SLAL: 111653388(hgf) 111671911
HCQ: 109523797 109526843(hgf)
BPEC: 110161457 110166846
MALB: 109959804 109967266(hgf)
SASA: 106561209 106573447 106576483 106609646
OTW: 112245248 112252444
SALP: 111962524 112075847
ELS: 105018431 105020379
SFM: 108921145(hgf) 108936428
PKI: 111833314 111846155(hgf)
LCM: 102354206(HGF)
CMK: 103177006(hgf)
RTP: 109921451(hgf)
 » show all
Reference
PMID:2528952
  Authors
Miyazawa K, Tsubouchi H, Naka D, Takahashi K, Okigaki M, Arakaki N, Nakayama H, Hirono S, Sakiyama O, Takahashi K, et al.
  Title
Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor.
  Journal
Biochem Biophys Res Commun 163:967-73 (1989)
DOI:10.1016/0006-291X(89)92316-4
  Sequence
[hsa:3082]
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