KEGG   ORTHOLOGY: K05460Help
Entry
K05460                      KO                                     

Name
HGF
Definition
hepatocyte growth factor
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko05144  Malaria
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05211  Renal cell carcinoma
ko05218  Melanoma
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00048  Hepatocellular carcinoma
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05460  HGF; hepatocyte growth factor
   04015 Rap1 signaling pathway
    K05460  HGF; hepatocyte growth factor
   04010 MAPK signaling pathway
    K05460  HGF; hepatocyte growth factor
   04151 PI3K-Akt signaling pathway
    K05460  HGF; hepatocyte growth factor
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05460  HGF; hepatocyte growth factor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05460  HGF; hepatocyte growth factor
   05205 Proteoglycans in cancer
    K05460  HGF; hepatocyte growth factor
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K05460  HGF; hepatocyte growth factor
   05226 Gastric cancer
    K05460  HGF; hepatocyte growth factor
   05218 Melanoma
    K05460  HGF; hepatocyte growth factor
   05211 Renal cell carcinoma
    K05460  HGF; hepatocyte growth factor
  09174 Infectious disease: parasitic
   05144 Malaria
    K05460  HGF; hepatocyte growth factor
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05460  HGF; hepatocyte growth factor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05460  HGF; hepatocyte growth factor
   00536 Glycosaminoglycan binding proteins
    K05460  HGF; hepatocyte growth factor
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K05460  HGF; hepatocyte growth factor
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Growth factors/receptors
   K05460  HGF; hepatocyte growth factor
BRITE hierarchy
Other DBs
GO: 0005171
Genes
HSA: 3082(HGF)
PTR: 463503(HGF)
PPS: 100983117(HGF)
GGO: 101127877(HGF)
PON: 100462115(HGF)
NLE: 100586296(HGF)
MCC: 708316(HGF)
MCF: 102133907(HGF)
CSAB: 103226643(HGF)
RRO: 104681576(HGF)
RBB: 108536940(HGF)
CJC: 100385966(HGF)
SBQ: 101045517(HGF)
MMU: 15234(Hgf)
MCAL: 110294216(Hgf)
MPAH: 110316234(Hgf)
RNO: 24446(Hgf)
MUN: 110565312(Hgf)
CGE: 100764472(Hgf)
NGI: 103730723(Hgf)
HGL: 101707056(Hgf)
OCU: 100316908(HGF)
TUP: 102483689(HGF)
CFA: 403441(HGF)
VVP: 112925397(HGF)
AML: 100463560(HGF)
UMR: 103658669(HGF)
UAH: 113259246(HGF)
ORO: 101373766(HGF)
FCA: 493705(HGF)
PTG: 102952318(HGF)
AJU: 106975661(HGF)
BTA: 282879(HGF)
BOM: 102267837(HGF)
BIU: 109557878(HGF)
BBUB: 102406209(HGF)
PHD: 102316675(HGF)
CHX: 102183288(HGF)
OAS: 443075(HGF)
SSC: 100525120(HGF)
CFR: 102515749(HGF)
BACU: 102997605
LVE: 103079072(HGF)
OOR: 101273491(HGF)
DLE: 111164604(HGF)
PCAD: 102992196(HGF)
ECB: 100049848(HGF)
EPZ: 103563173(HGF)
EAI: 106840178(HGF)
MYB: 102259449(HGF)
MYD: 102765945(HGF)
MNA: 107527167(HGF)
HAI: 109392334(HGF)
RSS: 109455385(HGF)
DRO: 112301961(HGF)
PALE: 102884470(HGF)
RAY: 107501285(HGF)
LAV: 100665493(HGF)
TMU: 101344799
MDO: 100016122(HGF)
SHR: 100915696(HGF)
PCW: 110206952(HGF)
OAA: 100074892(HGF)
GGA: 395941(HGF)
MGP: 100542153(HGF)
CJO: 107321440(HGF)
NMEL: 110392449(HGF)
APLA: 101793664(HGF)
ACYG: 106035566(HGF)
TGU: 100218784(HGF)
LSR: 110469773(HGF)
SCAN: 103813737(HGF)
GFR: 102042539(HGF)
FAB: 101810717(HGF)
PHI: 102106058(HGF)
PMAJ: 107205229(HGF)
CCAE: 111923284 111923285(HGF)
CCW: 104686934(HGF)
ETL: 114058724(HGF)
FPG: 101917184(HGF)
FCH: 102052167(HGF)
CLV: 102084988(HGF)
EGZ: 104132389(HGF)
NNI: 104010752(HGF)
ACUN: 113491250(HGF)
PADL: 103920599(HGF)
AAM: 106485602(HGF)
ASN: 102385607(HGF)
AMJ: 102564574(HGF)
PSS: 102451409(HGF)
CMY: 102929769(HGF)
CPIC: 101946945(HGF)
ACS: 100566618(hgf)
PVT: 110077194(HGF)
PBI: 103063662
GJA: 107110492(HGF)
XLA: 108711206(hgf.L) 108713062(hgf.S)
XTR: 100495840(hgf)
NPR: 108792728(HGF)
DRE: 100334116 493781(hgfa)
IPU: 108264660(HGF)
PHYP: 113534821(hgf)
LCO: 104918123(hgf) 104918795
NCC: 104952156(hgf) 104958230
MZE: 101470516(hgf) 101486965
OLA: 101156453 101167035(hgf)
XMA: 102226489(hgf) 102232629
XCO: 114136644(hgf) 114161125
PRET: 103459222 103466001(hgf)
NFU: 107385652 107388871(hgf)
KMR: 108229905(hgf) 108235047
AOCE: 111563989 111564882(hgf)
CSEM: 103380100(hgf) 103382777
POV: 109624365(hgf) 109632742
SDU: 111224573 111228480(hgf)
HCQ: 109523797 109526843(hgf)
MALB: 109959804 109967266(hgf)
SFM: 108921145(hgf) 108936428
PKI: 111833314 111846155(hgf)
LCM: 102354206(HGF)
CMK: 103177006(hgf)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2528952
  Authors
Miyazawa K, Tsubouchi H, Naka D, Takahashi K, Okigaki M, Arakaki N, Nakayama H, Hirono S, Sakiyama O, Takahashi K, et al.
  Title
Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor.
  Journal
Biochem Biophys Res Commun 163:967-73 (1989)
DOI:10.1016/0006-291X(89)92316-4
  Sequence
[hsa:3082]
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