KEGG   ORTHOLOGY: K05640Help
Entry
K05640                      KO                                     

Name
GFAP
Definition
glial fibrillary acidic protein
Pathway
ko04630  JAK-STAT signaling pathway
Disease
H00065  Alexander disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K05640  GFAP; glial fibrillary acidic protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05640  GFAP; glial fibrillary acidic protein
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05640  GFAP; glial fibrillary acidic protein
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Other CMA associated proteins
    K05640  GFAP; glial fibrillary acidic protein
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type III
     K05640  GFAP; glial fibrillary acidic protein
BRITE hierarchy
Genes
HSA: 2670(GFAP)
PTR: 454741(GFAP)
PPS: 100978176(GFAP)
GGO: 101139543(GFAP)
PON: 100172719(GFAP)
NLE: 100605452(GFAP)
MCC: 712941(GFAP)
MCF: 101926850(GFAP)
CSAB: 103243304(GFAP)
RRO: 104654731(GFAP)
RBB: 108532203(GFAP)
CJC: 100393644(GFAP)
SBQ: 101048514(GFAP)
MMU: 14580(Gfap)
MCAL: 110305792(Gfap)
MPAH: 110331730(Gfap)
RNO: 24387(Gfap)
MUN: 110545655(Gfap)
CGE: 100758767(Gfap)
NGI: 103738305(Gfap)
HGL: 101707892(Gfap)
CCAN: 109691423(Gfap)
OCU: 100352532(GFAP)
TUP: 102503416(GFAP)
CFA: 480495(GFAP)
VVP: 112910631(GFAP)
AML: 100464741(GFAP)
UMR: 103665875(GFAP)
UAH: 113265338(GFAP)
ORO: 101365936(GFAP)
FCA: 101081938(GFAP)
PTG: 102954891(GFAP)
AJU: 106988141(GFAP)
BTA: 281189(GFAP)
BOM: 102274398(GFAP)
BIU: 109574014(GFAP)
BBUB: 102409328(GFAP)
PHD: 102323325(GFAP)
CHX: 102190069(GFAP)
OAS: 443220(GFAP)
SSC: 396562(GFAP)
CFR: 102524034(GFAP)
CDK: 105094414(GFAP)
BACU: 103018855(GFAP)
LVE: 103079395(GFAP)
OOR: 101272327(GFAP)
DLE: 111170230(GFAP)
PCAD: 102986439(GFAP)
ECB: 100033970(GFAP)
EPZ: 103551220(GFAP)
EAI: 106836467(GFAP)
MYB: 102257790(GFAP)
MYD: 102758796(GFAP)
MNA: 107528850(GFAP)
HAI: 109394949(GFAP)
RSS: 109458535(GFAP)
DRO: 112298604(GFAP)
PALE: 102895484(GFAP)
RAY: 107508155(GFAP)
LAV: 100660211(GFAP) 104846295
TMU: 101345443
MDO: 100020340(GFAP)
SHR: 100933739(GFAP)
PCW: 110215851(GFAP)
GGA: 419969(GFAP)
MGP: 100550976(GFAP)
CJO: 107325021(GFAP)
NMEL: 110388574(GFAP)
APLA: 101797424(GFAP)
ACYG: 106046917(GFAP)
LSR: 110475598(GFAP)
SCAN: 103821780(GFAP)
FAB: 101818343(GFAP)
PHI: 102100154(GFAP)
PMAJ: 107215059(GFAP)
CCAE: 111940038(GFAP)
CCW: 104698521(GFAP)
ETL: 114071353(GFAP)
FPG: 101911447(GFAP)
FCH: 102050376(GFAP)
CLV: 102089384(GFAP)
EGZ: 104126003(GFAP)
NNI: 104018906(GFAP)
PADL: 103920633(GFAP)
AAM: 106481993(GFAP)
ASN: 102384862(GFAP)
AMJ: 102564977(GFAP)
CMY: 102940278(GFAP)
CPIC: 101934830(GFAP)
ACS: 100560464(gfap)
PVT: 110081395(GFAP)
PBI: 103054065(GFAP)
PMUR: 107286291(GFAP)
GJA: 107122503(GFAP)
DRE: 30646(gfap)
SANH: 107658466
IPU: 108274370(gfap)
PHYP: 113528593(gfap)
AMEX: 103035120(gfap)
EEE: 113580201(gfap)
TRU: 101072320
LCO: 104930223
NCC: 104943597(gfap)
MZE: 101468392
OLA: 101173548
XMA: 102235379
XCO: 114160222
PRET: 103468924
NFU: 107378535
KMR: 108237771
AOCE: 111588886
CSEM: 103392664
POV: 109634259
LCF: 108880565
SDU: 111217500
BPEC: 110164430
MALB: 109963200
OTW: 112258958
SALP: 111981350
ELS: 105012973
PKI: 111837635
LCM: 102348420(GFAP)
CMK: 103189656
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chen MH, Hagemann TL, Quinlan RA, Messing A, Perng MD
  Title
Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation.
  Journal
ASN Neuro 5:e00125 (2013)
DOI:10.1042/AN20130032
  Sequence
[hsa:2670]
LinkDB All DBs

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