KEGG   ORTHOLOGY: K05733Help
Entry
K05733                      KO                                     

Name
PAK3, MRX30
Definition
p21-activated kinase 3 [EC:2.7.11.1]
Pathway
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04660  T cell receptor signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05170  Human immunodeficiency virus 1 infection
ko05211  Renal cell carcinoma
Disease
H00480  X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05733  PAK3, MRX30; p21-activated kinase 3
   04012 ErbB signaling pathway
    K05733  PAK3, MRX30; p21-activated kinase 3
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05733  PAK3, MRX30; p21-activated kinase 3
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05733  PAK3, MRX30; p21-activated kinase 3
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K05733  PAK3, MRX30; p21-activated kinase 3
  09158 Development and regeneration
   04360 Axon guidance
    K05733  PAK3, MRX30; p21-activated kinase 3
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K05733  PAK3, MRX30; p21-activated kinase 3
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05733  PAK3, MRX30; p21-activated kinase 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05733  PAK3, MRX30; p21-activated kinase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05733  PAK3, MRX30; p21-activated kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05733  PAK3, MRX30; p21-activated kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE20 family
   K05733  PAK3, MRX30; p21-activated kinase 3
BRITE hierarchy
Genes
HSA: 5063(PAK3)
PTR: 450118(PAK3)
PPS: 100988375(PAK3)
GGO: 101141425(PAK3)
PON: 100294571(PAK3)
NLE: 100592637(PAK3)
MCC: 706217(PAK3)
MCF: 101866329(PAK3)
CSAB: 103232488(PAK3)
RRO: 104658196 104668306
CJC: 100413676(PAK3)
SBQ: 101030350(PAK3)
MMU: 18481(Pak3)
MCAL: 110286479(Pak3)
MPAH: 110314031(Pak3)
RNO: 29433(Pak3)
CGE: 100774215(Pak3)
NGI: 103750017(Pak3)
HGL: 101712811(Pak3)
CCAN: 109683839
OCU: 100347273(PAK3)
TUP: 102500036(PAK3)
CFA: 492067(PAK3)
VVP: 112932007(PAK3)
AML: 100481001(PAK3)
UMR: 103679739(PAK3)
UAH: 113241242(PAK3)
ORO: 101367940(PAK3)
FCA: 101092248(PAK3)
PTG: 102960506(PAK3)
AJU: 106985609(PAK3)
BTA: 534526(PAK3)
BOM: 102274792(PAK3)
BIU: 109555415(PAK3)
BBUB: 102391225(PAK3)
PHD: 102330386(PAK3)
CHX: 102183402(PAK3)
OAS: 101110391(PAK3)
SSC: 100624533(PAK3)
CFR: 102517603(PAK3)
CDK: 105102082(PAK3)
BACU: 103011843(PAK3)
LVE: 103077310(PAK3)
OOR: 101272214(PAK3)
DLE: 111165746(PAK3)
PCAD: 102978462(PAK3)
ECB: 100054315(PAK3)
EPZ: 103566208(PAK3)
EAI: 106839173(PAK3)
MYB: 102250915(PAK3)
MYD: 102755275(PAK3)
MNA: 107525908(PAK3)
HAI: 109392102(PAK3)
DRO: 112296895(PAK3)
PALE: 102886090(PAK3)
RAY: 107502306(PAK3) 107504604
LAV: 100668837(PAK3)
TMU: 101352984
MDO: 100012727(PAK3)
SHR: 100926699
PCW: 110203451(PAK3)
OAA: 100073584(PAK3)
GGA: 422342(PAK3)
MGP: 100539360(PAK3)
CJO: 107312836(PAK3)
NMEL: 110403309(PAK3)
APLA: 101796600(PAK3)
ACYG: 106038527(PAK3)
TGU: 100218271 100220716(PAK3)
GFR: 102042620(PAK3)
FPG: 101915790(PAK3)
FCH: 102049349(PAK3)
CLV: 102088276(PAK3)
EGZ: 104135693(PAK3)
NNI: 104023254(PAK3)
ACUN: 113479919(PAK3)
PADL: 103920160(PAK3)
AAM: 106494786(PAK3)
ASN: 102383228(PAK3)
AMJ: 102571123(PAK3)
PSS: 102455282(PAK3)
CMY: 102944295(PAK3)
CPIC: 101948199(PAK3)
ACS: 100552681(pak3)
PVT: 110074346(PAK3)
PBI: 103051014(PAK3)
PMUR: 107295917
GJA: 107106346(PAK3)
XLA: 108700104 378493(pak3.L)
XTR: 100495025(pak3)
NPR: 108796965
SRX: 107712492
SGH: 107566210
CCAR: 109078806
IPU: 108260344
PHYP: 113531410
AMEX: 103043289
EEE: 113586857
TRU: 101070991
LCO: 104935297
MZE: 101484450
OLA: 101162700
XMA: 102230909
XCO: 114152839
PRET: 103475835
NFU: 107386444
KMR: 108245238
AOCE: 111574262
CSEM: 103395561(pak3)
POV: 109628598
LCF: 108893764
SDU: 111234276
HCQ: 109517832
BPEC: 110158383
MALB: 109959578
OTW: 112228863
ELS: 105030442
LCM: 102350692 102367518(PAK3)
CMK: 103178926(pak3)
SPU: 576091
CRG: 105329587
PDAM: 113665712
SPIS: 111342446
HMG: 100205313
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9731525
  Authors
Allen KM, Gleeson JG, Bagrodia S, Partington MW, MacMillan JC, Cerione RA, Mulley JC, Walsh CA
  Title
PAK3 mutation in nonsyndromic X-linked mental retardation.
  Journal
Nat Genet 20:25-30 (1998)
DOI:10.1038/1675
  Sequence
[hsa:5063]
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