KEGG   ORTHOLOGY: K05736
Entry
K05736                      KO                                     

Name
PAK5, PAK7
Definition
p21-activated kinase 5 [EC:2.7.11.1]
Pathway
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04660  T cell receptor signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05170  Human immunodeficiency virus 1 infection
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K05736  PAK5, PAK7; p21-activated kinase 5
   04014 Ras signaling pathway
    K05736  PAK5, PAK7; p21-activated kinase 5
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05736  PAK5, PAK7; p21-activated kinase 5
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05736  PAK5, PAK7; p21-activated kinase 5
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K05736  PAK5, PAK7; p21-activated kinase 5
  09158 Development and regeneration
   04360 Axon guidance
    K05736  PAK5, PAK7; p21-activated kinase 5
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K05736  PAK5, PAK7; p21-activated kinase 5
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05736  PAK5, PAK7; p21-activated kinase 5
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05736  PAK5, PAK7; p21-activated kinase 5
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05736  PAK5, PAK7; p21-activated kinase 5
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE20 family
   K05736  PAK5, PAK7; p21-activated kinase 5
Genes
HSA: 57144(PAK5)
PTR: 469876(PAK5)
PPS: 100979774(PAK5)
GGO: 101124352(PAK5)
PON: 100174593(PAK7)
NLE: 100579630(PAK5)
MCC: 719458(PAK5)
MCF: 101926721(PAK5)
CSAB: 103246560(PAK5)
RRO: 104655775(PAK5)
RBB: 108527563(PAK5)
CJC: 100411048(PAK5)
SBQ: 101045496(PAK7)
MMU: 241656(Pak5)
MCAL: 110289454(Pak5)
MPAH: 110317761(Pak5)
RNO: 311450(Pak7)
MUN: 110540522(Pak5)
CGE: 100770198(Pak5)
NGI: 103729196(Pak5)
HGL: 101697197(Pak5)
CCAN: 109688863(Pak5)
OCU: 100340742(PAK5)
TUP: 102474805(PAK5)
CFA: 485772(PAK5)
VVP: 112930051(PAK5)
AML: 100481254(PAK5)
UMR: 103674429(PAK5)
UAH: 113258241(PAK5)
ORO: 101362594(PAK7)
ELK: 111141714
FCA: 101091011(PAK5)
PTG: 102959873(PAK5)
PPAD: 109274718(PAK5)
AJU: 106976429(PAK5)
BTA: 513432(PAK5)
BOM: 102288324(PAK5)
BIU: 109567943(PAK5)
BBUB: 102414520(PAK5)
CHX: 102181217(PAK5)
OAS: 101107882(PAK5)
SSC: 100152316(PAK5)
CFR: 102512936(PAK5)
CDK: 105101260(PAK5)
BACU: 102999931(PAK5)
LVE: 103077706(PAK5)
OOR: 101271942(PAK7)
DLE: 111165611(PAK5)
PCAD: 102996458(PAK5)
ECB: 100051415(PAK5)
EPZ: 103559731(PAK5)
EAI: 106823207(PAK5)
MYB: 102240345(PAK5)
MYD: 102752532(PAK5)
MNA: 107536364(PAK7)
HAI: 109378999(PAK5)
DRO: 112303959(PAK5)
PALE: 102884535(PAK5)
RAY: 107497004(PAK7)
MJV: 108388552 108394258(PAK5)
LAV: 100666744(PAK5)
TMU: 101361889
MDO: 100033279(PAK5)
SHR: 100932749(PAK5)
PCW: 110208060(PAK5) 110210302
OAA: 100084350(PAK5)
GGA: 416734(PAK5)
MGP: 100547824(PAK5)
CJO: 107310935(PAK5)
NMEL: 110395539(PAK5)
APLA: 101789812(PAK5)
ACYG: 106036610(PAK7)
TGU: 100224879(PAK5)
LSR: 110475843(PAK5)
SCAN: 103819231(PAK5)
GFR: 102045516(PAK5)
FAB: 101810542(PAK5)
PHI: 102100245(PAK5)
PMAJ: 107201333(PAK5)
CCAE: 111926462(PAK5)
CCW: 104691523(PAK5)
ETL: 114057360(PAK5)
FPG: 101917292(PAK5)
FCH: 102054246(PAK5)
CLV: 102098855(PAK5)
EGZ: 104132996(PAK7)
NNI: 104022435(PAK7)
ACUN: 113478339(PAK5)
PADL: 103913122(PAK7)
AAM: 106490395(PAK5)
ASN: 102376998(PAK5)
AMJ: 102558433(PAK5)
PSS: 102456678(PAK5)
CMY: 102943132(PAK5)
CPIC: 101953291(PAK5)
ACS: 100560563(pak5)
PVT: 110090819(PAK5)
PBI: 103058150(PAK5)
PMUR: 107285367(PAK5)
TSR: 106542667(PAK7)
PMUA: 114593660(PAK5)
GJA: 107123895(PAK5)
XTR: 100145129(pak5)
NPR: 108795532(PAK5)
DRE: 405898(pak5)
SGH: 107557903 107564328(pak7)
CCAR: 109113709(pak5)
IPU: 108257526(pak5)
PHYP: 113545324(pak5)
AMEX: 103023523(pak5)
EEE: 113589839
TRU: 101065597(pak5)
LCO: 104919803(pak5)
NCC: 104949786(pak7)
MZE: 101463583(pak5)
ONL: 100697856(pak5)
OLA: 101159788(pak5)
XMA: 102223306(pak5)
XCO: 114158365(pak5)
PRET: 103457878(pak5)
CVG: 107097299(pak7)
NFU: 107378108(pak7)
KMR: 108231823(pak5)
ALIM: 106533843
AOCE: 111575575(pak5)
CSEM: 103381003(pak7)
POV: 109632382(pak5)
LCF: 108896930(pak5)
SDU: 111216376(pak5)
SLAL: 111672671(pak5)
HCQ: 109523359(pak5)
BPEC: 110168289(pak5)
MALB: 109962210(pak5)
ELS: 105017523(pak5)
SFM: 108929398(pak5)
PKI: 111837469(pak5)
LCM: 102347021(PAK5)
CMK: 103186430(pak5) 103187528(pak6)
RTP: 109935293(pak5)
CIN: 100175395
SPU: 587831
APLC: 110988957
SKO: 100378766
DME: Dmel_CG18582(mbt)
DER: 6549994
DSE: 6617959
DSI: Dsimw501_GD17288(Dsim_GD17288)
DAN: 6503937
DSR: 110181507
DPO: Dpse_GA15000(Dpse_mbt)
DPE: 6599117
DMN: 108161337
DWI: 6648869
MDE: 101893437
LCQ: 111674999
AAG: 5566181
AALB: 109401286
AME: 726405
BIM: 100744101
BTER: 100643434
CCAL: 108630317
OBB: 114873671
SOC: 105193946
MPHA: 105835041
AEC: 105147967
ACEP: 105623486
PBAR: 105430497
VEM: 105558584
HST: 105191062
DQU: 106741955
CFO: 105249243
LHU: 105676520
PGC: 109859795
OBO: 105277512
PCF: 106790017
NVI: 100115383
CSOL: 105365235
MDL: 103579745
FCD: 110844300
PVM: 113822797
TUT: 107371299
DPTE: 113792197
CSCU: 111621119
PTEP: 107451326
CRG: 105342389
MYI: 110466349
SHX: MS3_05477
AQU: 100639104
 » show all
Reference
  Authors
Wu X, Carr HS, Dan I, Ruvolo PP, Frost JA
  Title
p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.
  Journal
J Cell Biochem 105:167-75 (2008)
DOI:10.1002/jcb.21809
Reference
  Authors
Li X, Minden A
  Title
Targeted disruption of the gene for the PAK5 kinase in mice.
  Journal
Mol Cell Biol 23:7134-42 (2003)
DOI:10.1128/MCB.23.20.7134-7142.2003
  Sequence
[mmu:241656]
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