KEGG   ORTHOLOGY: K05767
Entry
K05767                      KO                                     

Name
IQGAP2_3
Definition
Ras GTPase-activating-like protein IQGAP2/3
Pathway
ko04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
   04147 Exosome
    K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
  Exosomal proteins of colorectal cancer cells
   K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
Genes
HSA: 10788(IQGAP2) 128239(IQGAP3)
PTR: 457397(IQGAP3) 461801(IQGAP2)
PPS: 100974131(IQGAP3) 100974171(IQGAP2)
GGO: 101144088(IQGAP2) 101150753(IQGAP3)
PON: 100446817(IQGAP2) 100458843(IQGAP3)
NLE: 100583673(IQGAP3) 100606982(IQGAP2)
MCC: 712026(IQGAP2) 719575(IQGAP3)
MCF: 101926387(IQGAP2) 102141491(IQGAP3)
CSAB: 103223348(IQGAP2) 103223856(IQGAP3)
RRO: 104653745(IQGAP2) 104656734(IQGAP3)
RBB: 108513073(IQGAP2) 108515569(IQGAP3)
CJC: 100400958(IQGAP2) 100407513(IQGAP3)
SBQ: 101042420(IQGAP3) 101048366(IQGAP2)
MMU: 404710(Iqgap3) 544963(Iqgap2)
MCAL: 110290953(Iqgap3) 110308367(Iqgap2)
MPAH: 110319828(Iqgap3) 110329290(Iqgap2)
RNO: 100360623(Iqgap2) 310621(Iqgap3)
MUN: 110548964(Iqgap3) 110551087(Iqgap2)
CGE: 100754110(Iqgap3) 100761545(Iqgap2)
NGI: 103750454(Iqgap3) 103752272(Iqgap2)
HGL: 101707718(Iqgap2) 101716052(Iqgap3)
CCAN: 109683300 109686196(Iqgap3) 109701101(Iqgap2)
OCU: 100008918(IQGAP2) 100338069(IQGAP3)
TUP: 102482276(IQGAP3) 102486325(IQGAP2)
CFA: 479177(IQGAP2) 490412(IQGAP3)
VVP: 112918953(IQGAP3) 112919744(IQGAP2)
AML: 100467617(IQGAP3) 100482957(IQGAP2)
UMR: 103663860(IQGAP2) 103668684(IQGAP3)
UAH: 113245228(IQGAP3) 113255190(IQGAP2)
ORO: 101365302(IQGAP3) 101368777(IQGAP2)
FCA: 101082373(IQGAP2) 101082799(IQGAP3)
PTG: 102960907(IQGAP2) 102965815(IQGAP3)
PPAD: 109256337(IQGAP3) 109274975(IQGAP2)
AJU: 106974826(IQGAP2) 106981500(IQGAP3)
BTA: 505886(IQGAP3) 782315(IQGAP2)
BOM: 102272634(IQGAP2) 102285260(IQGAP3)
BIU: 109553189(IQGAP3) 109564647(IQGAP2)
BBUB: 102396036(IQGAP2) 102410027(IQGAP3)
CHX: 102171711(IQGAP2) 102175345(IQGAP3)
OAS: 101105506(IQGAP2) 101108447(IQGAP3)
SSC: 100515079(IQGAP3) 100521253(IQGAP2)
CFR: 102510258(IQGAP3) 102520205(IQGAP2)
CDK: 105084809(IQGAP2) 105105642(IQGAP3)
BACU: 103001626(IQGAP3) 103006862(IQGAP2)
LVE: 103076279(IQGAP3) 103078775(IQGAP2)
OOR: 101277833(IQGAP2) 101278534(IQGAP3)
DLE: 111167143(IQGAP3) 111185193(IQGAP2)
PCAD: 102983135(IQGAP2) 102995192(IQGAP3)
ECB: 100064268(IQGAP3) 100073279(IQGAP2)
EPZ: 103548855(IQGAP3)
EAI: 106824014(IQGAP2) 106828460(IQGAP3)
MYB: 102239639(IQGAP2) 102243841(IQGAP3)
MYD: 102754963(IQGAP2) 102774244(IQGAP3)
MNA: 107531210(IQGAP2) 107543865(IQGAP3)
HAI: 109381897(IQGAP2) 109393367(IQGAP3)
DRO: 112307546(IQGAP2) 112314473(IQGAP3)
PALE: 102882352(IQGAP3) 102892349(IQGAP2)
RAY: 107501528 107521519(IQGAP3)
MJV: 108383340(IQGAP3) 108383643(IQGAP2)
LAV: 100665906(IQGAP3) 100668714(IQGAP2)
SHR: 100920110(IQGAP2) 100924928(IQGAP3)
PCW: 110212120(IQGAP3) 110216638(IQGAP2)
OAA: 100083169(IQGAP2) 103168426(IQGAP3)
GGA: 101749531(RGI3L1) 427211(IQGAP2)
MGP: 100543341(IQGAP2)
CJO: 107306056(IQGAP2)
NMEL: 110389338(IQGAP2)
APLA: 101791572(IQGAP2) 101799307(IQGAP3)
ACYG: 106042102(IQGAP2) 106048962
TGU: 100218311(IQGAP3) 100230235(IQGAP2)
LSR: 110471291(IQGAP2) 110471506(IQGAP3)
SCAN: 103819493(IQGAP2) 103824066(IQGAP3)
GFR: 102031406(IQGAP2) 102035941(IQGAP3)
FAB: 101810013(IQGAP2) 101812599(IQGAP3)
PHI: 102100569(IQGAP3) 102109090(IQGAP2)
PMAJ: 107214597(IQGAP3) 107216413(IQGAP2)
CCAE: 111939451(IQGAP3) 111940722(IQGAP2)
ETL: 114057035(IQGAP2) 114069938(IQGAP3)
FPG: 101916578(IQGAP2) 101922356(IQGAP3)
FCH: 102048006(IQGAP3) 102051089(IQGAP2)
CLV: 102089748(IQGAP2) 102093287
EGZ: 104124865(IQGAP2) 104132644
NNI: 104011886(IQGAP3) 104013344(IQGAP2)
ACUN: 113489569(IQGAP2) 113490526
PADL: 103913905(IQGAP3) 103919755(IQGAP2)
AAM: 106492289(IQGAP3)
ASN: 102370483(IQGAP2) 102385543(IQGAP3)
AMJ: 102559625(IQGAP3) 102565155(IQGAP2)
PSS: 102458413(IQGAP3) 102461710
CMY: 102930365(IQGAP2) 102937736(IQGAP3)
CPIC: 101932819(IQGAP3) 101934758(IQGAP2)
ACS: 100566858(iqgap2)
PVT: 110084593(IQGAP2) 110090223(IQGAP3)
PBI: 103064146(IQGAP2) 103067498(IQGAP3)
PMUR: 107290910(IQGAP3) 107293561(IQGAP2)
TSR: 106539009(IQGAP2) 106557195(IQGAP3)
PMUA: 114586384(IQGAP3) 114606150(IQGAP2)
GJA: 107118046(IQGAP3) 107123149(IQGAP2)
XLA: 108699395(iqgap3.L) 108717898 398588(iqgap2.S)
XTR: 100124996(iqgap2) 100488901(iqgap3)
NPR: 108794907 108795384(IQGAP2)
DRE: 100537977(iqgap3) 563030(iqgap2)
IPU: 108255686(iqgap2) 108270714(iqgap3)
PHYP: 113536960(iqgap2) 113542330
AMEX: 103027753(iqgap2) 103038102
EEE: 113571234(iqgap3) 113580494(iqgap2)
TRU: 101071761(iqgap2) 101076722
NCC: 104963556
MZE: 101479965(iqgap2) 101481140
ONL: 100705988(iqgap2) 100712425(iqgap3)
OLA: 101157782(iqgap2)
XMA: 102229602(iqgap2) 102238089
XCO: 114142050 114155036(iqgap2)
PRET: 103470429(iqgap2) 103477456(iqgap3)
NFU: 107379231(iqgap3) 107393890(iqgap2)
KMR: 108234580(iqgap2) 108250194(iqgap3)
ALIM: 106510950 106517520(iqgap2)
AOCE: 111576004(iqgap2) 111587884
CSEM: 103388046(iqgap3) 103398128(iqgap2)
POV: 109638153(iqgap2)
LCF: 108878179(iqgap2) 108884708
SDU: 111228359(iqgap2) 111234089
SLAL: 111644710 111660315(iqgap2)
BPEC: 110156677(iqgap2) 110157879
MALB: 109956885(iqgap2)
ELS: 105014330(iqgap2) 105031059
SFM: 108938090 108941879(iqgap3)
PKI: 111836075 111838398(iqgap3)
LCM: 102349627(IQGAP2)
CMK: 103186381(iqgap2)
RTP: 109914159
CEL: CELE_F09C3.1(pes-7)
CBR: CBG18782(Cbr-pes-7)
NVE: 5512688
EPA: 110242009
AMIL: 114954401
PDAM: 113685102
SPIS: 111330587
DGT: 114528067
HMG: 100198420
AQU: 100632534
SCE: YPL242C(IQG1)
ERC: Ecym_2146
KMX: KLMA_50342(IQG1)
NCS: NCAS_0G01170(NCAS0G01170)
NDI: NDAI_0F01300(NDAI0F01300)
TPF: TPHA_0D03530(TPHA0D03530)
TBL: TBLA_0A02270(TBLA0A02270)
TDL: TDEL_0A06820(TDEL0A06820)
KAF: KAFR_0F01110(KAFR0F01110)
CAL: CAALFM_C701840WA(IQG1)
SLB: AWJ20_3527(IQG1) AWJ20_826(IRA1)
NTE: NEUTE1DRAFT133299(NEUTE1DRAFT_133299)
ANG: ANI_1_1012064(An07g08210) ANI_1_500144(An16g03580)
PNO: SNOG_00420 SNOG_03102(SNOG_03101)
SPO: SPAC4F8.13c(rng2) SPBC646.12c(gap1)
CNE: CNB02580
ABP: AGABI1DRAFT120329(AGABI1DRAFT_120329) AGABI1DRAFT59753(AGABI1DRAFT_59753)
ABV: AGABI2DRAFT202767(AGABI2DRAFT_202767) AGABI2DRAFT218479(AGABI2DRAFT_218479)
DFA: DFA_04018(gapA)
EHI: EHI_035800(17.t00065)
 » show all
Reference
PMID:8756646
  Authors
Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ
  Title
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.
  Journal
Mol Cell Biol 16:4869-78 (1996)
DOI:10.1128/MCB.16.9.4869
  Sequence
[hsa:10788]
Reference
  Authors
Wang S, Watanabe T, Noritake J, Fukata M, Yoshimura T, Itoh N, Harada T, Nakagawa M, Matsuura Y, Arimura N, Kaibuchi K
  Title
IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth.
  Journal
J Cell Sci 120:567-77 (2007)
DOI:10.1242/jcs.03356
  Sequence
[hsa:128239] [rno:310621]
Reference
PMID:9382845
  Authors
Epp JA, Chant J
  Title
An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast.
  Journal
Curr Biol 7:921-9 (1997)
DOI:10.1016/S0960-9822(06)00411-8
  Sequence
[sce:YPL242C]
LinkDB

DBGET integrated database retrieval system