KEGG   ORTHOLOGY: K06268Help
Entry
K06268                      KO                                     

Name
PPP3R, CNB
Definition
serine/threonine-protein phosphatase 2B regulatory subunit
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04114  Oocyte meiosis
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04370  VEGF signaling pathway
ko04380  Osteoclast differentiation
ko04625  C-type lectin receptor signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05031  Amphetamine addiction
ko05152  Tuberculosis
ko05163  Human cytomegalovirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04310 Wnt signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04370 VEGF signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04020 Calcium signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04022 cGMP-PKG signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04218 Cellular senescence
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04650 Natural killer cell mediated cytotoxicity
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04660 T cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04658 Th1 and Th2 cell differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04659 Th17 cell differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04662 B cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04921 Oxytocin signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04924 Renin secretion
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09156 Nervous system
   04724 Glutamatergic synapse
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04720 Long-term potentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09158 Development and regeneration
   04360 Axon guidance
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04380 Osteoclast differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05014 Amyotrophic lateral sclerosis (ALS)
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09165 Substance dependence
   05031 Amphetamine addiction
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05170 Human immunodeficiency virus 1 infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05163 Human cytomegalovirus infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05167 Kaposi sarcoma-associated herpesvirus infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
BRITE hierarchy
Other DBs
COG: COG5126
GO: 0004723
Genes
HSA: 5534(PPP3R1) 5535(PPP3R2)
PTR: 100613118(PPP3R1) 736325(PPP3R2)
PPS: 100995767(PPP3R2)
GGO: 101144871(PPP3R2)
PON: 100461146(PPP3R2) 103889825(PPP3R1)
NLE: 100593195(PPP3R1) 100600788(PPP3R2)
MCC: 100428682(PPP3R1) 574258(PPP3R2)
MCF: 101866439(PPP3R2) 102137250(PPP3R1)
CSAB: 103219106(PPP3R2) 103220127(PPP3R1)
RRO: 104670806(PPP3R2) 104675975(PPP3R1)
RBB: 108537161(PPP3R2)
CJC: 100388148(PPP3R1) 100392986(PPP3R2)
SBQ: 101039659(PPP3R2) 104650539(PPP3R1)
MMU: 19058(Ppp3r1) 19059(Ppp3r2)
MCAL: 110293037(Ppp3r2) 110304839(Ppp3r1)
MPAH: 110322987(Ppp3r2) 110330477(Ppp3r1)
RNO: 29748(Ppp3r1) 29749(Ppp3r2)
MUN: 110558957(Ppp3r1) 110561325
CGE: 100754314(Ppp3r2) 100773706(Ppp3r1)
NGI: 103734750(Ppp3r1) 103749104(Ppp3r2)
HGL: 101706255(Ppp3r1) 101710684(Ppp3r2)
CCAN: 109693705(Ppp3r1) 109696247(Ppp3r2)
OCU: 100344533(PPP3R2)
TUP: 102474096(PPP3R1) 102478386(PPP3R2)
CFA: 610453(PPP3R2) 612559(PPP3R1)
VVP: 112930770(PPP3R2) 112934379(PPP3R1)
AML: 100467683(PPP3R1) 100474742(PPP3R2)
UMR: 103671340(PPP3R1) 103678534(PPP3R2)
UAH: 113244743(PPP3R1) 113260378(PPP3R2)
ORO: 101368686(PPP3R2) 101386271(PPP3R1)
FCA: 101090344(PPP3R1) 101097765(PPP3R2)
PTG: 102965200(PPP3R1) 102967427(PPP3R2)
AJU: 106967692(PPP3R1) 106972076(PPP3R2)
BTA: 282321(PPP3R1) 617585(PPP3R2)
BOM: 102272271(PPP3R1) 102277736(PPP3R2)
BIU: 109563306(PPP3R2) 109566227(PPP3R1)
BBUB: 102400804(PPP3R2) 102406798(PPP3R1)
PHD: 102325503(PPP3R2) 102332014(PPP3R1)
CHX: 102177339(PPP3R2) 102182602(PPP3R1)
OAS: 101120802(PPP3R2) 114108765(PPP3R1)
SSC: 100625117(PPP3R2) 100627903(PPP3R1)
CFR: 106729683(PPP3R2)
BACU: 103009602(PPP3R2)
LVE: 103068473(PPP3R1) 103078845(PPP3R2)
OOR: 101272877(PPP3R1) 105748080(PPP3R2)
DLE: 111186607(PPP3R1) 111188120(PPP3R2)
PCAD: 112065477(PPP3R2) 112067521(PPP3R1)
ECB: 100061874(PPP3R1) 102148270(PPP3R2)
EPZ: 103548960(PPP3R1) 103552460(PPP3R2)
EAI: 106828340(PPP3R1) 106831788(PPP3R2)
MYB: 102247129(PPP3R2) 102250711(PPP3R1)
MYD: 102760712(PPP3R2) 102774846(PPP3R1)
MNA: 107545969(PPP3R1)
HAI: 109379237(PPP3R1)
DRO: 112297858(PPP3R1) 112304508(PPP3R2)
PALE: 102894471(PPP3R1) 102895490(PPP3R2)
RAY: 107499586(PPP3R2) 107506933(PPP3R1)
LAV: 100668807(PPP3R2) 111751572(PPP3R1)
MDO: 100033302(PPP3R1)
SHR: 100918689(PPP3R1)
PCW: 110207663(PPP3R1)
OAA: 100083665(PPP3R1)
GGA: 378804(PPP3R1)
MGP: 100549150(PPP3R1)
CJO: 107310666(PPP3R1)
NMEL: 110396552(PPP3R1)
APLA: 101791746(PPP3R1)
ACYG: 106044692(PPP3R1)
TGU: 100229058(PPP3R1)
LSR: 110484892(PPP3R1)
SCAN: 103821361(PPP3R1)
GFR: 102034017(PPP3R1)
FAB: 101820532(PPP3R1)
PHI: 102111343(PPP3R1)
PMAJ: 107201468(PPP3R1)
CCAE: 111926640(PPP3R1)
CCW: 104696602(PPP3R1)
ETL: 114054864(PPP3R1)
FPG: 101923629(PPP3R1)
FCH: 102050745(PPP3R1)
CLV: 102095954(PPP3R1)
EGZ: 104129247(PPP3R1)
NNI: 104018925(PPP3R1)
ACUN: 113478143(PPP3R1)
PADL: 103917815(PPP3R1)
AAM: 106495909(PPP3R1)
ASN: 102377091(PPP3R1)
AMJ: 106737480(PPP3R1)
PSS: 102448775(PPP3R1)
ACS: 100561213(ppp3r1)
PVT: 110091682(PPP3R1)
PBI: 107326860(PPP3R1)
GJA: 107114939(PPP3R1)
XLA: 108716580(ppp3r1.L) 399215(ppp3r1.S)
XTR: 395037(ppp3r1)
NPR: 108795656(PPP3R1)
DRE: 447814(ppp3r1b) 564337(ppp3r1a)
IPU: 108258530 108263224(ppp3r1)
PHYP: 113537343 113541892(ppp3r1)
EEE: 113579658 113585612(ppp3r1)
TRU: 101071292 101074110(ppp3r1)
LCO: 104918540 104930901(ppp3r1)
NCC: 104954071(ppp3r1)
MZE: 101465581 101487274(ppp3r1)
OLA: 101161991(ppp3r1) 101168674
XMA: 102218918(ppp3r1)
XCO: 114137969(ppp3r1)
PRET: 103472014 103476469(ppp3r1)
NFU: 107376079(ppp3r1)
KMR: 108247263(ppp3r1)
AOCE: 111570968(ppp3r1)
CSEM: 103386871(ppp3r1)
POV: 109634942(ppp3r1) 109645661
LCF: 108873404(ppp3r1) 108888732
SDU: 111227385(ppp3r1) 111237590
HCQ: 109508548 109526689(ppp3r1)
BPEC: 110157106(ppp3r1) 110173890
MALB: 109961064(ppp3r1)
ELS: 105021516 106024317(ppp3r1)
PKI: 111850760(ppp3r1) 111859769
LCM: 102367157(PPP3R1)
CMK: 103177901(ppp3r1)
DME: Dmel_CG11217(CanB2) Dmel_CG4209(CanB)
DSI: Dsimw501_GD15356(Dsim_GD15356) Dsimw501_GD29162(Dsim_GD29162)
MDE: 101894267
LCQ: 111676949
AAG: 5573370
AME: 551313
BIM: 100749634
BTER: 100650453
SOC: 105201645
MPHA: 105835317
AEC: 105144936
ACEP: 105624663
PBAR: 105422521
HST: 105182789
DQU: 106747742
CFO: 105250886
LHU: 105678532
PGC: 109851930
OBO: 105276504
PCF: 106788783
NVI: 100121135
MDL: 103579881
TCA: 664163
DPA: 109542598
NVL: 108556329
BMOR: 692578(Cnb)
PMAC: 106708445
PRAP: 110991898
HAW: 110369812
TNL: 113496220
PXY: 105380958
API: 100162564
DNX: 107163945
BTAB: 109033461
CLEC: 106673033
ZNE: 110826606
FCD: 110842725
TUT: 107372011
DPTE: 113793164
CEL: CELE_F55C10.1(cnb-1)
CBR: CBG23183(Cbr-cnb-1)
BMY: Bm1_50880
TSP: Tsp_02876
PCAN: 112570556
MYI: 110459429
OBI: 106878873
SHX: MS3_08636
EGL: EGR_02530
HMG: 100213359
AQU: 100640962
ATH: AT1G64480(CBL8) AT3G18430 AT4G01420(CBL5) AT4G16350(CBL6) AT4G17615(CBL1) AT4G26560(CBL7) AT4G26570(CBL3) AT4G33000(CBL10) AT5G24270(SOS3) AT5G47100(CBL9) AT5G55990(CBL2)
LJA: Lj0g3v0205869.1(Lj0g3v0205869.1) Lj1g3v0984330.1(Lj1g3v0984330.1) Lj1g3v0984330.2(Lj1g3v0984330.2) Lj1g3v0984330.3(Lj1g3v0984330.3) Lj2g3v1988900.1(Lj2g3v1988900.1) Lj2g3v3318760.1(Lj2g3v3318760.1) Lj3g3v0044110.1(Lj3g3v0044110.1) Lj3g3v0044110.2(Lj3g3v0044110.2) Lj3g3v2442020.1(Lj3g3v2442020.1) Lj3g3v2442020.2(Lj3g3v2442020.2) Lj3g3v2693160.2(Lj3g3v2693160.2) Lj4g3v0095240.2(Lj4g3v0095240.2) Lj4g3v1202210.1(Lj4g3v1202210.1) Lj4g3v2002950.1(Lj4g3v2002950.1) Lj4g3v3014180.1(Lj4g3v3014180.1) Lj4g3v3014180.2(Lj4g3v3014180.2) Lj5g3v0391490.1(Lj5g3v0391490.1) Lj6g3v0704520.1(Lj6g3v0704520.1) Lj6g3v1707200.1(Lj6g3v1707200.1)
VVI: 100243294(CBL01) 100244675 100246874(CBL04) 100249564(CBL05) 100254259(CBL07) 100254683(CBL08) 100259377(CBL06) 100260894(CBL01) 100262221(CBL03) 100263924 100266945(CBL02) 104878144
DOSA: Os01t0579600-01(Os01g0579600) Os01t0598200-01(Os01g0598200) Os01t0711500-00(Os01g0711500) Os02t0291000-00(Os02g0291000) Os02t0291400-00(Os02g0291400) Os02t0480800-00(Os02g0480800) Os02t0802400-01(Os02g0802400) Os03t0448500-01(Os03g0448500) Os03t0626800-01(Os03g0626800) Os05t0534400-01(Os05g0534400) Os08t0442300-01(Os08g0442300) Os08t0442350-01(Os08g0442350) Os10t0564800-01(Os10g0564800) Os12t0162400-01(Os12g0162400) Os12t0597000-01(Os12g0597000)
ATS: 109732811(LOC109732811) 109733825(LOC109733825) 109739617(LOC109739617) 109740273 109742945(LOC109742945) 109744414(LOC109744414) 109748696(LOC109748696) 109756485(LOC109756485) 109761304(LOC109761304) 109762527(LOC109762527) 109763262(LOC109763262) 109763576(LOC109763576) 109770914(LOC109770914) 109780615(LOC109780615) 109787363(LOC109787363)
SCE: YKL190W(CNB1)
ERC: Ecym_7012
KMX: KLMA_10636(CNB1)
NCS: NCAS_0A02710(NCAS0A02710)
NDI: NDAI_0D04640(NDAI0D04640)
TPF: TPHA_0B01930(TPHA0B01930)
TBL: TBLA_0I03160(TBLA0I03160)
TDL: TDEL_0H01410(TDEL0H01410)
KAF: KAFR_0A05790(KAFR0A05790)
CAL: CAALFM_C505160CA(CNB1)
SLB: AWJ20_4204(CNB1)
NCR: NCU03833(cnb-1)
NTE: NEUTE1DRAFT144368(NEUTE1DRAFT_144368)
MGR: MGG_06933
SSCK: SPSK_05470
TRE: TRIREDRAFT_52130(calb)
MAW: MAC_00460
MAJ: MAA_07344
CMT: CCM_03871
BFU: BCIN_03g05990(Bccnb1)
MBE: MBM_08246
ANI: AN6566.2
ANG: ANI_1_152134(An15g00870)
ABE: ARB_04150
TVE: TRV_03941
PTE: PTT_18349
ZTR: MYCGRDRAFT_68731(CANB)
CNE: CND00260
CNB: CNBD5950
PPL: POSPLDRAFT_109275(CAR1)
ABP: AGABI1DRAFT116228(AGABI1DRAFT_116228)
ABV: AGABI2DRAFT135141(AGABI2DRAFT_135141)
MGL: MGL_1603
DDI: DDB_G0267446(cnbA) DDB_G0285999(cnbB)
DFA: DFA_07623(cnbA)
EHI: EHI_106670(217.t00005)
PYO: PY17X_1319200(PY01623)
PCB: PCHAS_131870(PC001255.02.0)
CPV: cgd1_1370
SMIN: v1.2.028178.t1(symbB.v1.2.028178.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2558868
  Authors
Guerini D, Krinks MH, Sikela JM, Hahn WE, Klee CB
  Title
Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.
  Journal
DNA 8:675-82 (1989)
DOI:10.1089/dna.1.1989.8.675
  Sequence
[hsa:5534]
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