KEGG   ORTHOLOGY: K06493Help
Entry
K06493                      KO                                     

Name
ITGB3, CD61
Definition
integrin beta 3
Pathway
ko04015  Rap1 signaling pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04380  Osteoclast differentiation
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04611  Platelet activation
ko04640  Hematopoietic cell lineage
ko04810  Regulation of actin cytoskeleton
ko04919  Thyroid hormone signaling pathway
ko05163  Human cytomegalovirus infection
ko05165  Human papillomavirus infection
ko05168  Herpes simplex virus 1 infection
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
ko05418  Fluid shear stress and atherosclerosis
Disease
H00083  Allograft rejection
H00226  Glanzmann thrombasthenia
H01740  Macrothrombocytopenia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
   04151 PI3K-Akt signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06493  ITGB3, CD61; integrin beta 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06493  ITGB3, CD61; integrin beta 3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06493  ITGB3, CD61; integrin beta 3
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K06493  ITGB3, CD61; integrin beta 3
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06493  ITGB3, CD61; integrin beta 3
   04611 Platelet activation
    K06493  ITGB3, CD61; integrin beta 3
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06493  ITGB3, CD61; integrin beta 3
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K06493  ITGB3, CD61; integrin beta 3
   05205 Proteoglycans in cancer
    K06493  ITGB3, CD61; integrin beta 3
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K06493  ITGB3, CD61; integrin beta 3
   05410 Hypertrophic cardiomyopathy (HCM)
    K06493  ITGB3, CD61; integrin beta 3
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06493  ITGB3, CD61; integrin beta 3
   05414 Dilated cardiomyopathy (DCM)
    K06493  ITGB3, CD61; integrin beta 3
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K06493  ITGB3, CD61; integrin beta 3
   05163 Human cytomegalovirus infection
    K06493  ITGB3, CD61; integrin beta 3
   05165 Human papillomavirus infection
    K06493  ITGB3, CD61; integrin beta 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06493  ITGB3, CD61; integrin beta 3
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06493  ITGB3, CD61; integrin beta 3
   04515 Cell adhesion molecules
    K06493  ITGB3, CD61; integrin beta 3
   04090 CD molecules
    K06493  ITGB3, CD61; integrin beta 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K06493  ITGB3, CD61; integrin beta 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06493  ITGB3, CD61; integrin beta 3
Cell adhesion molecules [BR:ko04515]
 Integrins
  Integrin beta subunits
   K06493  ITGB3, CD61; integrin beta 3
CD molecules [BR:ko04090]
 Proteins
  K06493  CD61, ITGB3; integrin, beta 3
BRITE hierarchy
Genes
HSA: 3690(ITGB3)
PTR: 468295(ITGB3)
PPS: 100974497(ITGB3)
GGO: 101149719(ITGB3)
PON: 100445345(ITGB3)
NLE: 100593791(ITGB3)
MCC: 717379(ITGB3)
MCF: 102117791(ITGB3)
CSAB: 103243277(ITGB3)
RRO: 104662513(ITGB3)
RBB: 108536294(ITGB3)
CJC: 100386042(ITGB3)
SBQ: 101049562(ITGB3)
MMU: 16416(Itgb3)
MCAL: 110305072(Itgb3)
MPAH: 110331915(Itgb3)
RNO: 29302(Itgb3)
MUN: 110545659(Itgb3)
CGE: 100775048(Itgb3)
NGI: 103724762(Itgb3)
HGL: 101715910(Itgb3)
CCAN: 109696588(Itgb3)
OCU: 100008735(ITGB3)
TUP: 102486101(ITGB3)
CFA: 403788(ITGB3)
VVP: 112920636(ITGB3)
AML: 100476256(ITGB3)
UMR: 103665892(ITGB3)
UAH: 113265309(ITGB3)
ORO: 101369957(ITGB3)
FCA: 101092159(ITGB3)
PTG: 102963673(ITGB3)
AJU: 106988847(ITGB3)
BTA: 282642(ITGB3)
BOM: 102268918(ITGB3)
BIU: 109574140(ITGB3)
BBUB: 102391335(ITGB3)
PHD: 102334258(ITGB3)
CHX: 102169417(ITGB3)
OAS: 100423047(ITGB3)
SSC: 397063(ITGB3)
CFR: 102512014(ITGB3)
CDK: 105090426(ITGB3)
BACU: 103005345(ITGB3)
LVE: 103070292(ITGB3)
OOR: 101275188(ITGB3)
DLE: 111182589(ITGB3)
PCAD: 102988740(ITGB3)
ECB: 100009709(ITGB3)
EPZ: 103560746(ITGB3)
EAI: 106843793(ITGB3)
MYB: 102242014(ITGB3)
MYD: 102761706(ITGB3)
MNA: 107530883(ITGB3)
HAI: 109380323(ITGB3)
RSS: 109448085(ITGB3)
DRO: 112316322(ITGB3)
PALE: 102881894(ITGB3)
RAY: 107501647
LAV: 100660405(ITGB3)
TMU: 101359355
MDO: 100025359(ITGB3)
SHR: 100920734(ITGB3)
PCW: 110215904(ITGB3)
OAA: 100087119(ITGB3)
GGA: 374209(ITGB3)
MGP: 100540307(ITGB3)
CJO: 107325258(ITGB3)
NMEL: 110388544(ITGB3)
APLA: 101803666(ITGB3)
ACYG: 106045987(ITGB3)
TGU: 100226539(ITGB3)
LSR: 110476970(ITGB3)
SCAN: 103821681(ITGB3)
GFR: 102043377(ITGB3)
FAB: 101806454(ITGB3)
PHI: 102114571(ITGB3)
PMAJ: 107215302(ITGB3)
CCAE: 111940101(ITGB3)
CCW: 104698490(ITGB3)
ETL: 114066945(ITGB3)
FPG: 101924792(ITGB3)
FCH: 102048772(ITGB3)
CLV: 102089259(ITGB3)
EGZ: 104134605(ITGB3)
NNI: 104009899(ITGB3)
ACUN: 113489245(ITGB3)
PADL: 103926075(ITGB3)
AAM: 106485378 106485578
ASN: 102372699(ITGB3)
AMJ: 102570288(ITGB3)
PSS: 102444998
CMY: 102930769 102933265(ITGB3)
CPIC: 101953490(ITGB3)
ACS: 100560980(itgb3) 103282820
PVT: 110081384(ITGB3)
PBI: 103060352(ITGB3)
PMUR: 107303035(ITGB3)
GJA: 107109989 107112937
XLA: 397699(itgb3.L)
XTR: 100498495(itgb3)
NPR: 108797421(ITGB3)
DRE: 100001836(itgb3b)
SRX: 107706862 107727289 107754700
SANH: 107660728 107698806 107700113
SGH: 107552441 107552749(itgb3) 107568162 107578913 107579941
CCAR: 109099440 109100178 109113681
IPU: 108274212(itgb3) 108279461(Itgb3)
PHYP: 113527252 113528642
AMEX: 103028095 103043996
EEE: 113572826(itgb3) 113573277
TRU: 101069582 101075584
TNG: GSTEN00013326G001 GSTEN00021802G001 GSTEN00022070G001
LCO: 104926218 104930968(itgb3)
NCC: 104949146(itgb3) 104953334 104967625
MZE: 101467289 101471236(itgb3)
OLA: 101161193(itgb3) 101168465
XMA: 102221802 102227385(itgb3)
XCO: 114151891(itgb3) 114160108
PRET: 103469372 103481277(itgb3)
NFU: 107378581 107387874
KMR: 108243758 108248812
AOCE: 111567286(itgb3) 111584896
CSEM: 103381463(itgb3) 103393124
POV: 109627018(itgb3) 109634031
LCF: 108872765 108898731
SDU: 111217494 111219935(itgb3)
HCQ: 109508858 109523958 109532691
BPEC: 110154280(itgb3) 110161461
MALB: 109963088 109964262
SASA: 106579149 106600998 106607266
OTW: 112223770 112258603
SALP: 112068256 112068719
ELS: 105006835 105013321
SFM: 108919139(itgb3) 108941817
PKI: 111856058 111856113(itgb3)
LCM: 102349935(ITGB3)
CMK: 103187732(itgb3)
CRG: 105328932 105346726
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3494014
  Authors
Fitzgerald LA, Steiner B, Rall SC Jr, Lo SS, Phillips DR
  Title
Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin".
  Journal
J Biol Chem 262:3936-9 (1987)
  Sequence
[hsa:3690]
Reference
PMID:9195946
  Authors
Kumar CS, James IE, Wong A, Mwangi V, Feild JA, Nuthulaganti P, Connor JR, Eichman C, Ali F, Hwang SM, Rieman DJ, Drake FH, Gowen M
  Title
Cloning and characterization of a novel integrin beta3 subunit.
  Journal
J Biol Chem 272:16390-7 (1997)
DOI:10.1074/jbc.272.26.16390
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