KEGG   ORTHOLOGY: K06590Help
Entry
K06590                      KO                                     

Name
ITGB7
Definition
integrin beta 7
Pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04514  Cell adhesion molecules (CAMs)
ko04672  Intestinal immune network for IgA production
ko04810  Regulation of actin cytoskeleton
ko05165  Human papillomavirus infection
ko05202  Transcriptional misregulation in cancer
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K06590  ITGB7; integrin beta 7
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06590  ITGB7; integrin beta 7
   04514 Cell adhesion molecules (CAMs)
    K06590  ITGB7; integrin beta 7
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06590  ITGB7; integrin beta 7
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K06590  ITGB7; integrin beta 7
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    K06590  ITGB7; integrin beta 7
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K06590  ITGB7; integrin beta 7
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K06590  ITGB7; integrin beta 7
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06590  ITGB7; integrin beta 7
   05414 Dilated cardiomyopathy (DCM)
    K06590  ITGB7; integrin beta 7
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K06590  ITGB7; integrin beta 7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06590  ITGB7; integrin beta 7
   04515 Cell adhesion molecules
    K06590  ITGB7; integrin beta 7
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06590  ITGB7; integrin beta 7
Cell adhesion molecules [BR:ko04515]
 Integrins
  Integrin beta subunits
   K06590  ITGB7; integrin beta 7
BRITE hierarchy
Genes
HSA: 3695(ITGB7)
PTR: 451934(ITGB7)
PPS: 100989804(ITGB7)
GGO: 101145271(ITGB7)
PON: 100440010(ITGB7)
NLE: 100590097(ITGB7)
MCC: 699405(ITGB7)
MCF: 102137082(ITGB7)
CSAB: 103238384(ITGB7)
RRO: 104670606(ITGB7)
RBB: 108521588(ITGB7)
CJC: 100402863(ITGB7)
SBQ: 101028462(ITGB7)
MMU: 16421(Itgb7)
MCAL: 110310547(Itgb7)
MPAH: 110334491(Itgb7)
RNO: 25713(Itgb7)
MUN: 110552301(Itgb7)
CGE: 100770075(Itgb7)
NGI: 103738472(Itgb7)
HGL: 101719620(Itgb7)
CCAN: 109684070(Itgb7)
OCU: 100350557(ITGB7)
TUP: 102469446(ITGB7)
CFA: 477598(ITGB7)
VVP: 112921264(ITGB7)
AML: 100474212(ITGB7)
UMR: 103675667(ITGB7)
UAH: 113257564(ITGB7)
ORO: 101371307(ITGB7)
FCA: 101099982(ITGB7)
PTG: 102956549(ITGB7)
AJU: 106986437(ITGB7)
BTA: 514031(ITGB7)
BOM: 102285452(ITGB7)
BIU: 109559043(ITGB7)
BBUB: 102396110(ITGB7)
PHD: 102343070(ITGB7)
CHX: 102180190(ITGB7)
OAS: 101109956(ITGB7)
CFR: 102509667(ITGB7)
CDK: 105094574(ITGB7)
BACU: 103006205(ITGB7)
LVE: 103081453(ITGB7)
OOR: 101289968(ITGB7)
DLE: 111173950(ITGB7)
PCAD: 102976793(ITGB7)
ECB: 100063747(ITGB7)
EPZ: 103559421(ITGB7)
EAI: 106835324(ITGB7)
MYD: 102754396(ITGB7)
MNA: 107528299(ITGB7)
HAI: 109391828(ITGB7)
RSS: 109443745(ITGB7)
DRO: 112318624(ITGB7)
PALE: 102896485(ITGB7)
RAY: 107509843(ITGB7)
LAV: 100661118(ITGB7)
TMU: 101357623
SHR: 100920489(ITGB7)
PCW: 110194074(ITGB7)
OAA: 100087765(ITGB7)
GGA: 107049666
CJO: 107306950(ITGB7)
NMEL: 110390876(ITGB7)
ASN: 102378313(ITGB7)
AMJ: 102573931(ITGB7)
PSS: 102459674
CMY: 102934106(ITGB7)
CPIC: 101940453(ITGB7)
ACS: 100566599(itgb7)
PVT: 110070338(ITGB7)
PBI: 103048661(ITGB7)
PMUR: 107288518(ITGB7)
GJA: 107118966(ITGB7)
XLA: 108708650(itgb7.L)
XTR: 100486332(itgb7)
NPR: 108786823(ITGB7)
SGH: 107582697 107585205(itgb7)
CCAR: 109063479
IPU: 108271744
PHYP: 113545835(itgb7)
AMEX: 103047301
EEE: 113575940(itgb7)
SFM: 108918430(itgb7) 108939200
PKI: 111858768(itgb7)
LCM: 102367083(ITGB7)
CMK: 103171689
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2083230
  Authors
Yuan QA, Jiang WM, Krissansen GW, Watson JD
  Title
Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains.
  Journal
Int Immunol 2:1097-108 (1990)
DOI:10.1093/intimm/2.11.1097
  Sequence
[hsa:3695]
Reference
  Authors
Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J
  Title
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
  Journal
Proc Natl Acad Sci U S A 106:20877-82 (2009)
DOI:10.1073/pnas.0911796106
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