KEGG   ORTHOLOGY: K06626Help
Entry
K06626                      KO                                     

Name
CCNE
Definition
G1/S-specific cyclin-E1
Pathway
ko04110  Cell cycle
ko04114  Oocyte meiosis
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04391  Hippo signaling pathway - fly
ko04934  Cushing syndrome
ko05161  Hepatitis B
ko05162  Measles
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05206  MicroRNAs in cancer
ko05215  Prostate cancer
ko05222  Small cell lung cancer
ko05226  Gastric cancer
Disease
H00018  Gastric cancer
H00055  Laryngeal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04391 Hippo signaling pathway - fly
    K06626  CCNE; G1/S-specific cyclin-E1
   04151 PI3K-Akt signaling pathway
    K06626  CCNE; G1/S-specific cyclin-E1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06626  CCNE; G1/S-specific cyclin-E1
   04114 Oocyte meiosis
    K06626  CCNE; G1/S-specific cyclin-E1
   04115 p53 signaling pathway
    K06626  CCNE; G1/S-specific cyclin-E1
   04218 Cellular senescence
    K06626  CCNE; G1/S-specific cyclin-E1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05206 MicroRNAs in cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05203 Viral carcinogenesis
    K06626  CCNE; G1/S-specific cyclin-E1
  09162 Cancer: specific types
   05226 Gastric cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05215 Prostate cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05222 Small cell lung cancer
    K06626  CCNE; G1/S-specific cyclin-E1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K06626  CCNE; G1/S-specific cyclin-E1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06626  CCNE; G1/S-specific cyclin-E1
   05162 Measles
    K06626  CCNE; G1/S-specific cyclin-E1
   05161 Hepatitis B
    K06626  CCNE; G1/S-specific cyclin-E1
   05169 Epstein-Barr virus infection
    K06626  CCNE; G1/S-specific cyclin-E1
   05165 Human papillomavirus infection
    K06626  CCNE; G1/S-specific cyclin-E1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K06626  CCNE; G1/S-specific cyclin-E1
   03036 Chromosome and associated proteins
    K06626  CCNE; G1/S-specific cyclin-E1
DNA replication proteins [BR:ko03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    K06626  CCNE; G1/S-specific cyclin-E1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Cyclins
    K06626  CCNE; G1/S-specific cyclin-E1
BRITE hierarchy
Genes
HSA: 898(CCNE1) 9134(CCNE2)
PTR: 455914(CCNE1) 464292(CCNE2)
PPS: 100972365(CCNE1) 100982783(CCNE2)
GGO: 101134470(CCNE1) 101153263(CCNE2)
PON: 100438282(CCNE2) 100461587(CCNE1)
NLE: 100602200(CCNE2) 100607751(CCNE1)
MCC: 700382(CCNE2) 700589(CCNE1)
MCF: 102137714(CCNE1) 102138564(CCNE2)
CSAB: 103235482(CCNE1) 103237156(CCNE2)
RRO: 104656155(CCNE1) 104660331(CCNE2)
RBB: 108530611(CCNE1) 108539896(CCNE2)
CJC: 100396520(CCNE1) 100403750(CCNE2)
SBQ: 101036684(CCNE2) 101052282(CCNE1)
MMU: 12447(Ccne1) 12448(Ccne2)
MCAL: 110292124(Ccne2) 110298604(Ccne1)
MPAH: 110324083(Ccne1) 110338930(Ccne2)
RNO: 25729(Ccne1) 362485(Ccne2)
MUN: 110545702(Ccne1) 110561277(Ccne2)
CGE: 100753358(Ccne1) 100760464(Ccne2)
NGI: 103740830(Ccne1) 103745830(Ccne2)
HGL: 101701725(Ccne2) 101711961(Ccne1)
CCAN: 109693086(Ccne1) 109695602(Ccne2)
OCU: 100134864(CCNE1) 100134867(CCNE2)
TUP: 102468317(CCNE1) 102492088(CCNE2)
CFA: 484610(CCNE1) 487057(CCNE2)
VVP: 112928464(CCNE1) 112931227(CCNE2)
AML: 100471009(CCNE1) 100483627(CCNE2)
UMR: 103661328(CCNE1) 103661444(CCNE2)
UAH: 113244704(CCNE1) 113252919(CCNE2)
ORO: 101366323(CCNE2) 101382136(CCNE1)
FCA: 101085347(CCNE2) 101086192(CCNE1)
PTG: 102955833(CCNE2) 102966425(CCNE1)
PPAD: 109251568(CCNE1) 109269512(CCNE2)
AJU: 106974883(CCNE2) 106975766(CCNE1)
BTA: 533526(CCNE1) 538436(CCNE2)
BOM: 102271261(CCNE1) 102284697(CCNE2)
BIU: 109568476(CCNE2) 109572914(CCNE1)
BBUB: 102389005(CCNE1) 102390852(CCNE2)
CHX: 102184185(CCNE1) 102185672(CCNE2)
OAS: 101107124(CCNE1) 101109811(CCNE2)
SSC: 100512048(CCNE2) 100523248(CCNE1)
CFR: 102512815(CCNE2) 102516466(CCNE1)
CDK: 105085741(CCNE2) 105096784(CCNE1)
BACU: 102997538(CCNE2) 103008660(CCNE1)
LVE: 103078168(CCNE1) 103087546(CCNE2)
OOR: 101272657(CCNE1) 101285614(CCNE2)
DLE: 111180416(CCNE2) 111180958(CCNE1)
PCAD: 102980091(CCNE1) 102988829(CCNE2)
ECB: 100053882(CCNE1) 100055302(CCNE2)
EPZ: 103556279(CCNE1) 103567628(CCNE2)
EAI: 106831458(CCNE2) 106832401(CCNE1)
MYB: 102248984(CCNE2)
MYD: 102763547(CCNE2) 102769827(CCNE1)
MNA: 107534117(CCNE2) 107535865(CCNE1)
HAI: 109376215(CCNE2) 109383495(CCNE1)
DRO: 112296785(CCNE1) 112315543(CCNE2)
PALE: 102882260(CCNE1) 102882411(CCNE2)
RAY: 107502556(CCNE2) 107515884(CCNE1)
MJV: 108385232(CCNE1) 108396147(CCNE2)
LAV: 100659451(CCNE1) 100668342(CCNE2)
MDO: 100014623(CCNE1) 100022654(CCNE2)
SHR: 100920942(CCNE1) 100924454(CCNE2)
PCW: 110195790(CCNE2) 110207433(CCNE1)
OAA: 100075784(CCNE2) 100087197(CCNE1)
GGA: 420231(CCNE2) 426117(CCNE1)
MGP: 100539157 100545829(CCNE2)
CJO: 107310377(CCNE2) 107319346(CCNE1)
NMEL: 110393757(CCNE2) 110404443(CCNE1)
APLA: 101792020(CCNE2) 101792902(CCNE1)
ACYG: 106030499(CCNE2) 106039599(CCNE1)
TGU: 100220841(CCNE1)
LSR: 110476268(CCNE1) 110477449(CCNE2)
SCAN: 103813607(CCNE2) 103816602(CCNE1)
GFR: 102040569(CCNE1) 102043017(CCNE2)
FAB: 101809310(CCNE2) 101821269(CCNE1)
PHI: 102111744(CCNE2) 102114128(CCNE1)
PMAJ: 107200409(CCNE2) 107210040(CCNE1)
CCAE: 111924530(CCNE2) 111934658(CCNE1)
CCW: 104687430(CCNE1) 104692739(CCNE2)
ETL: 114060091(CCNE2) 114063486(CCNE1)
FPG: 101913703(CCNE2) 101923204(CCNE1)
FCH: 102047310(CCNE2) 102059423(CCNE1)
CLV: 102091343(CCNE1) 102094830(CCNE2)
EGZ: 104125564(CCNE1) 104125860(CCNE2)
NNI: 104013280(CCNE1) 104016423(CCNE2)
ACUN: 113476163(CCNE2) 113484462(CCNE1)
PADL: 103913786(CCNE1) 103917293(CCNE2)
AAM: 106483300(CCNE1) 106483881(CCNE2)
ASN: 102368597(CCNE2) 102382034(CCNE1)
AMJ: 102568414(CCNE2) 102569019(CCNE1)
PSS: 102445271(CCNE2) 102460990(CCNE1)
CMY: 102931864(CCNE2) 102941488(CCNE1)
CPIC: 101940805(CCNE1) 101946480(CCNE2)
ACS: 100553527(ccne1) 100563792(ccne2)
PVT: 110069793(CCNE1) 110074768(CCNE2)
PBI: 103052775(CCNE1) 103066008(CCNE2)
PMUR: 107289143(CCNE2) 107292735(CCNE1)
TSR: 106551743(CCNE2) 106555427(CCNE1) 106555428
PMUA: 114600411(CCNE2) 114602273(CCNE1)
GJA: 107109268(CCNE2) 107111199(CCNE1)
XLA: 380219(ccne2.L) 397840(ccne1.L) 397841(ccne1.S) 495419(ccne2.S)
XTR: 549021(ccne2) 549082(ccne1)
NPR: 108784132(CCNE1) 108795903(CCNE2)
DRE: 30188(ccne1) 415165(ccne2)
AMEX: 103028876 103030457(ccne2) 103042001(ccne1)
EEE: 113572719(ccne2) 113586489 113591781(ccne1)
OLA: 101155592(ccne1) 101172438(ccne2)
XMA: 102233990(ccne2) 102234620(ccne1)
XCO: 114139015(ccne2) 114142529(ccne1)
PRET: 103462253(ccne1) 103477592(ccne2)
CVG: 107086797 107092298(ccne2)
NFU: 107374180(ccne1) 107379284(ccne2)
KMR: 108237878(ccne1) 108240335(ccne2)
ALIM: 106516743(ccne1) 106524900(ccne2)
CSEM: 103378619(ccne1) 103388039(ccne2)
SLAL: 111644688(ccne2) 111649541 111672273(ccne1)
SASA: 100195405(ccne2) 100286718(ccne1) 106562012 106605376(ccne2)
ELS: 105019239(ccne2) 105022734(ccne1)
LCM: 102363290(CCNE2) 102366176(CCNE1) 106704504
CMK: 103175366(ccne2) 103176046(ccne1)
RTP: 109924247(ccne2) 109932834(ccne1)
CIN: 100185796
SPU: 579860
APLC: 110980132
SKO: 100371723
DME: Dmel_CG3938(CycE)
DER: 6542978
DSI: Dsimw501_GD21944(Dsim_GD21944)
DSR: 110185949
DPE: 6603382
DWI: 6644016
DAZ: 108611979
DHE: 111596331
MDE: 101893514
LCQ: 111684363
AAG: 5571432
AME: 411327
BIM: 100743743
BTER: 100643771
CCAL: 108622673
OBB: 114874054
SOC: 105195892
MPHA: 105831791
AEC: 105153804
ACEP: 105624868
PBAR: 105424288
VEM: 105560343
HST: 105184328
DQU: 106750123
CFO: 105252802
LHU: 105671051
PGC: 109855838
OBO: 105276425
PCF: 106791295
NVI: 100114765(cycE)
CSOL: 105361015
MDL: 103577463
TCA: 657290
DPA: 109536939
ATD: 109598037
NVL: 108566345
BMOR: 100216493(Cyce)
PMAC: 106713917
PRAP: 110994971
HAW: 110381830
TNL: 113496456
PXY: 105382581
API: 100159237
DNX: 107167038
AGS: 114125620
RMD: 113551412
BTAB: 109043120
ZNE: 110838908
FCD: 110842390
TUT: 107367273
DPTE: 113792814
PTEP: 107455437
CEL: CELE_C37A2.4(cye-1)
CBR: CBG12774(Cbr-cye-1)
PCAN: 112577049
CRG: 105332299
MYI: 110443792
EPA: 110253010
ADF: 107345701
PDAM: 113680591
SPIS: 111337022
DGT: 114517040
HMG: 100211715
AQU: 100634156
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK
  Title
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.
  Journal
Nature 413:311-6 (2001)
DOI:10.1038/35095068
  Sequence
Reference
PMID:1833068
  Authors
Koff A, Cross F, Fisher A, Schumacher J, Leguellec K, Philippe M, Roberts JM
  Title
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.
  Journal
Cell 66:1217-28 (1991)
DOI:10.1016/0092-8674(91)90044-Y
  Sequence
[hsa:898]
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