KEGG   ORTHOLOGY: K06856Help
Entry
K06856                      KO                                     

Name
IGH
Definition
immunoglobulin heavy chain
Pathway
ko04020  Calcium signaling pathway
ko04064  NF-kappa B signaling pathway
ko04072  Phospholipase D signaling pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04640  Hematopoietic cell lineage
ko04650  Natural killer cell mediated cytotoxicity
ko04662  B cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04666  Fc gamma R-mediated phagocytosis
ko04672  Intestinal immune network for IgA production
ko05130  Pathogenic Escherichia coli infection
ko05140  Leishmaniasis
ko05143  African trypanosomiasis
ko05146  Amoebiasis
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05169  Epstein-Barr virus infection
ko05202  Transcriptional misregulation in cancer
ko05310  Asthma
ko05320  Autoimmune thyroid disease
ko05322  Systemic lupus erythematosus
ko05323  Rheumatoid arthritis
ko05330  Allograft rejection
ko05340  Primary immunodeficiency
ko05414  Dilated cardiomyopathy (DCM)
ko05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K06856  IGH; immunoglobulin heavy chain
   04020 Calcium signaling pathway
    K06856  IGH; immunoglobulin heavy chain
   04072 Phospholipase D signaling pathway
    K06856  IGH; immunoglobulin heavy chain
   04151 PI3K-Akt signaling pathway
    K06856  IGH; immunoglobulin heavy chain
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06856  IGH; immunoglobulin heavy chain
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06856  IGH; immunoglobulin heavy chain
   04650 Natural killer cell mediated cytotoxicity
    K06856  IGH; immunoglobulin heavy chain
   04662 B cell receptor signaling pathway
    K06856  IGH; immunoglobulin heavy chain
   04664 Fc epsilon RI signaling pathway
    K06856  IGH; immunoglobulin heavy chain
   04666 Fc gamma R-mediated phagocytosis
    K06856  IGH; immunoglobulin heavy chain
   04672 Intestinal immune network for IgA production
    K06856  IGH; immunoglobulin heavy chain
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K06856  IGH; immunoglobulin heavy chain
  09163 Immune disease
   05310 Asthma
    K06856  IGH; immunoglobulin heavy chain
   05322 Systemic lupus erythematosus
    K06856  IGH; immunoglobulin heavy chain
   05323 Rheumatoid arthritis
    K06856  IGH; immunoglobulin heavy chain
   05320 Autoimmune thyroid disease
    K06856  IGH; immunoglobulin heavy chain
   05330 Allograft rejection
    K06856  IGH; immunoglobulin heavy chain
   05340 Primary immunodeficiency
    K06856  IGH; immunoglobulin heavy chain
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    K06856  IGH; immunoglobulin heavy chain
   05416 Viral myocarditis
    K06856  IGH; immunoglobulin heavy chain
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06856  IGH; immunoglobulin heavy chain
   05150 Staphylococcus aureus infection
    K06856  IGH; immunoglobulin heavy chain
   05152 Tuberculosis
    K06856  IGH; immunoglobulin heavy chain
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K06856  IGH; immunoglobulin heavy chain
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K06856  IGH; immunoglobulin heavy chain
   05140 Leishmaniasis
    K06856  IGH; immunoglobulin heavy chain
   05143 African trypanosomiasis
    K06856  IGH; immunoglobulin heavy chain
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06856  IGH; immunoglobulin heavy chain
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K06856  IGH; immunoglobulin heavy chain
BRITE hierarchy
Genes
HSA: 102723407(IGH)
PTR: 100608894
PPS: 100983622
GGO: 101126730
MCC: 721002
MCF: 102118733 102124047
CSAB: 103229828
RRO: 104664707
RBB: 108522153
MMU: 641025(CRP55H)
RNO: 691714(RGD1565478)
CGE: 100764817
OCU: 100009097(IGGC)
VVP: 112912798
BBUB: 112582881
SSC: 396781
OOR: 101287043
ECB: 100146643
MYB: 102253571
LSR: 110481636
CCAE: 111945990
ETL: 114073587
CLV: 102091146
PSS: 102462069
ACS: 100553338
PMUR: 107295545
DRE: 100535958(ighv4-5)
SRX: 107710248
IPU: 108275153
PHYP: 113546930
AOCE: 111585549
LCM: 102348584
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chaudhuri J, Basu U, Zarrin A, Yan C, Franco S, Perlot T, Vuong B, Wang J, Phan RT, Datta A, Manis J, Alt FW
  Title
Evolution of the immunoglobulin heavy chain class switch recombination mechanism.
  Journal
Adv Immunol 94:157-214 (2007)
DOI:10.1016/S0065-2776(06)94006-1
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